Abstract:
BACKGROUND:Marital status is one of the most frequently replicated predictors of suicide. The purpose of this study was to examine the effect of marital status on the risk of suicide by gender, using a large population-based cohort in Japan. METHODS:The Miyagi cohort study was a population-based, prospective cohort study of Japanese adults aged between 40 and 64 years. Between June and August 1990, 47,604 participants residing in 14 municipalities of Miyagi Prefecture, Japan, completed a questionnaire on various health-related lifestyles, including marital status. During 18 years of follow-up, 146 of the participants committed suicide. We used the Cox proportional hazards regression model to estimate the hazard ratios (HRs) and 95% confidence intervals (95% CIs) for suicide mortality according to marital status with adjustment for potential confounders. RESULTS:A total of 106 and 40 deaths from suicide were recorded during 344,813 and 365,524 person-years of follow-up among 20,671 men and 21,076 women, respectively. We found that marital status was significantly associated with the risk of completing suicide only in men. Among men, after multivariate adjustment, HRs in reference to married were as follows: widowed or divorced, 2.84 (95% CI: 1.37-5.90); unmarried, 1.56 (95% CI: 0.67-3.64). A significantly increased risk of suicidal death was observed among widowed or divorced men, whereas no such trend was evident for women. CONCLUSIONS:Our results suggest that men who are widowed or divorced, or unmarried, are at increased risk of suicide, whereas no such risk is evident for women.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Fukuchi N,Kakizaki M,Sugawara Y,Tanji F,Watanabe I,Fukao A,Tsuji Idoi
10.1016/j.jad.2013.05.006subject
Has Abstractpub_date
2013-09-25 00:00:00pages
879-85issue
3eissn
0165-0327issn
1573-2517pii
S0165-0327(13)00364-9journal_volume
150pub_type
杂志文章abstract:BACKGROUND:Although genetic influences on bipolar I disorder are well established, localization of genes that predispose to the illness has been difficult. Some genes predisposing to bipolar I disorder may be transmitted without expression of the categorical clinical phenotype. One strategy to overcome this obstacle is...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.07.017
更新日期:2010-05-01 00:00:00
abstract::Predicting response to antidepressant medication has been a challenge to clinicians and researchers for decades. Attention has been paid to the role of motor retardation as a putative indicator of treatment response, yet previous findings have been mixed. One reason for this inconsistency may be related to the subject...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(02)00107-6
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:The use of college students with high scores on a depression rating scale as analogues for depression by psychological researchers has generated controversy. Critics of analogue research argue that depression is qualitatively different in analogue and clinical samples. OBJECTIVE:To conduct a further compari...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00305-0
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Dysregulation of HPA axis has been widely described in subjects with bipolar disorder (BD), including changes in cortisol levels during mood episodes and euthymia. However, most of the studies were done with medicated BD patients with variable length of illness, which was shown to interfere on peripheral cor...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.11.046
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:The nature of the sleep disturbances associated with different phenotypes of pediatric bipolar disorder is unknown. Most manic children exhibit delayed sleep onset, but only a minority display decreased need for sleep. The DSM-IV manic sleep criterion is inadequate. METHOD:All published studies of the sleep...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2007.10.007
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:In some but not all women, periods of hormonal change may be associated with diversified physical, mental and cognitive symptoms that may be severe enough to warrant treatment. These reproductive-life periods include pregnancy, post-partum, the premenstrual and perimenopausal periods. CONCLUSIONS:Disorders ...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2009.05.018
更新日期:2010-04-01 00:00:00
abstract::347 patients with primary depressive illness were studied. Patients were classified on the Newcastle Diagnostic Scale and their depression was rated on the Hamilton Rating Scale for Depression (HRS) and self-rated on the Beck Depression Inventory (BDI). Clinical and personality factors were studied in relation to clas...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(84)90008-9
更新日期:1984-02-01 00:00:00
abstract:BACKGROUND:Central banks set economy-wide interest rates to meet exclusively economic objectives. There is a strong link between indebtedness and psychiatric morbidity at the individual level, with interest rates being an important factor determining ability to repay debt. However, no prior research has explored whethe...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.03.003
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Current estimates of the prevalence of depression in later life mostly arise from studies carried out in Europe, North America and Asia. In this study we aimed to measure the prevalence of depression using a standardised method in a number of low and middle income countries (LMIC). METHODS:A one-phase cross...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.09.004
更新日期:2016-01-15 00:00:00
abstract:BACKGROUND:Affective symptoms in Alzheimer's disease (AD) can be rated with both informant- and self-ratings. Information from these two modalities may not converge. We estimated network structures of affective symptoms in AD with both rating modalities and assessed the longitudinal stability of the networks. METHODS:...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.07.100
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Death by suicide is a preventable public health concern worldwide. The aim of this study is to investigate the probability of suicide death using baseline characteristics and simple medical facility visit history data using Cox regression, support vector machines (SVMs), and deep neural networks (DNNs). MET...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.01.019
更新日期:2018-04-15 00:00:00
abstract:BACKGROUND:Intimate partner violence (IPV) has a serious detrimental effect on mental health outcomes. We aimed to investigate the association of verbal or physical IPV with incidence of depressive symptoms in both married women and men according to the victim-perpetrator role. The potential mediating role of verbal or...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.11.041
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:The loss of an expected child is a psychologically difficult and potentially traumatic life event. While most women will become pregnant again within a year following the loss, data are limited regarding the mental health of parents with a history of perinatal loss, especially in the period following the bir...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.11.016
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Heightened threat sensitivity is a transdiagnostic feature in several psychiatric disorders. The neuropeptide oxytocin has been shown to reduce fear related behaviours and facilitated fear extinction in animals. These findings have led to increasing interest to explore the effects of intranasal oxytocin on t...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jad.2017.08.041
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Anxiety disorders have been related to cardiovascular diseases via low-grade inflammation, but longitudinal studies on the association between generalized anxiety disorder (GAD) and inflammatory biomarkers are sparse. Furthermore, no studies have examined the association between GAD and the "cardio-protectiv...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.03.123
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Individuals with bipolar disorder lead a sedentary lifestyle associated with worse course of illness and recurrence of symptoms. Identifying potentially modifiable predictors of exercise frequency could lead to interventions with powerful consequences on the course of illness and overall health. METHODS:The...
journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2013.07.031
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Self-reported data and media suggest youth mental health is declining. To more objectively measure this, we conducted a population-wide investigation of changes in diagnosed point prevalences of anxiety/depression among children and young adults between 1997 and 2017 in Ontario, Canada. METHODS:All Ontarian...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.12.178
更新日期:2020-12-30 00:00:00
abstract:BACKGROUND:Is it healthy to be chaotic? Recent studies have argued that mental disorders are associated with more orderly neural activities, corresponding to a less flexible functional system. These conclusions were derived from altered temporal complexity. However, the relationship between spatial complexity and healt...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.12.107
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Epidemiological and clinical studies have reported the frequent co-occurrence of social phobia (SP) and alcohol use disorders. Patients with SP often use alcohol to cope with the social situations they fear, and to lessen anticipatory anxiety, behavioral inhibition, and phobic avoidance. We investigated whet...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00316-5
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:Depression in later life frequently persists and perpetuating factors are of immediate therapeutic relevance to clinicians. No studies of this scale have examined both clinical and neuropsychological predictors of persistent depression in a cross-national European context. METHODS:4095 community dwelling ol...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.10.037
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Higher depressive symptoms have been associated with lower future income. However, studies examining this issue have had limited follow-up times and have used self-reported measures of income. Also, possible confounders or mediators have not been accounted. METHODS:971 women and 738 men were selected from t...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.06.028
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Ketamine has rapid-acting antidepressant and antisuicidal properties, while a proportion of patients do not adequately achieve a complete response to ketamine. Our aim was to explore the applicability of using clinical factors and serum tryptophan (TRP) metabolites to predict the response to six doses of ket...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.01.001
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Methylarginines are endogenous nitric oxide synthase inhibitors that have been implicated in depression. This study measured serum concentrations of l-arginine, asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in a representative sample of older community-dwelling adults and determined their associati...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.06.033
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:The study of temporal variation in self-harm is important to understanding the underlying mechanisms of its occurrence. There are fewer studies on temporal variation in self-harm than in suicide. The aim of this study was to examine the seasonality of self-harm in Hong Kong and to test the hypothesis of dimi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.09.025
更新日期:2017-01-01 00:00:00
abstract::Depression-related cognitive impairment (DRCI) is a condition which despite its initial treatment response, shows a progressive deterioration. No consistent therapeutic strategies have been proposed to combat this condition. This may be due to a reluctance to treat the cognitively impaired, a failure to recognise the ...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/0165-0327(95)00070-4
更新日期:1996-01-22 00:00:00
abstract:OBJECTIVE:Inflammatory cytokines have been suggested to be the trait or state markers of bipolar disorder, but with inconsistent results. This may be related to small sample sizes and poor control of some important confounding factors. METHODS:Gender/age-matched outpatients with bipolar disorder and normal controls we...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.009
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:In the present paper we describe a case-control study on the utilization of health care services prior to suicide (across different time periods) among children and adolescents aged 11 to 18 years in the Province of Quebec, Canada and matched healthy controls. METHOD:Utilization of services (i.e., contact wi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.01.004
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Age of onset is an important epidemiological indicator in characterizing disorders׳ subtypes according to demographic, clinical and psychosocial determinants. While investigated in various psychiatric conditions, age of onset and related characteristics in agoraphobia have yet to be examined. In light of the...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.03.064
更新日期:2015-07-15 00:00:00
abstract:OBJECTIVE:Suicide is a major cause of death in university students. Personality traits have been suggested as possible risk factors for suicidal behaviors. This study looked at the relationship between the personality dimensions of the Temperament and Character Inventory (TCI) and suicidal behaviors. METHOD:A total of...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.06.025
更新日期:2017-10-15 00:00:00
abstract::Research on adolescent and adult populations has linked depression to variation in several monoaminergic genes, but genetic association studies on depression in children are limited. Additionally, few studies have investigated whether stressors occurring very early in development moderate the influence of certain gene...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.03.023
更新日期:2016-06-01 00:00:00