Abstract:
BACKGROUND:The knowledge on bovine vaccines against respiratory viruses on bronchoalveolar fluid cells is scarce. OBJECTIVE:To compare the effects of a commercial intranasal (IN) and intramuscular (IM) vaccine against bovine respiratory disease (BRD) complex viruses on bronchoalveolar fluid cells of healthy heifers. METHODS:21 healthy heifers were assigned to three treatment groups: control (CO, N = 7), intranasally vaccinated (IN) (n = 7), and intramuscularly vaccinated (IM) (n = 7). The IN group received 1 mL of the commercial vaccine in each nostril once containing attenuated BoHV-1, bPIV-3, and BRSV. The IM group was vaccinated with two doses of 2 mL with an interval of 21 days of the commercial vaccine containing attenuated BoHV-1, bPIV-3, and BRSV plus inactivated BVDV. At day 0 (D0), before the first vaccine dose, and at D3, D7, and D21, after the last vaccine dose, airway bronchoscopy was performed to observe local irritation and collect bronchoalveolar lavage fluid (BALF). The bronchoalveolar count, cytological evaluation, bronchoalveolar cell oxidative metabolism, and total bronchoalveolar IgA and IgG were measured. RESULTS:The IN vaccine increased neutrophil cellularity at D7 and D21 and total IgA at D3 in BALF. Total IgA in BALF also increased at D3 and oxidative metabolism of bronchoalveolar cells at D21 lowered compared to the CO group. Following IM vaccination there was no alteration of immunoglobulins or cell oxidative metabolism in BALF. Both vaccines reduced the number of alveolar macrophages. CONCLUSION:Both vaccines induced bronchoalveolar inflammation during the establishment of the vaccine immunity, which was more expressive in the IN protocol.
journal_name
Vet Qjournal_title
The veterinary quarterlyauthors
Rossi PS,Mattei RI,Schllemer NR,Thomaz GR,Antunes AV,Virmond MP,Taube MJ,Bertagnon HGdoi
10.1080/01652176.2020.1870019keywords:
["BALF","Bovine","bovine respiratory complex (BRD)","bronchoalveolar lavage","heifer","vaccination"]subject
Has Abstractpub_date
2021-12-01 00:00:00pages
97-106issue
1eissn
0165-2176issn
1875-5941journal_volume
41pub_type
杂志文章相关文献
文献大全abstract::Brucellosis not only represents an important health restraint on livestock but also causes high economic losses in many developing countries worldwide. Despite considerable efforts made for the control of brucellosis, the disease is still spreading in many regions (such as the Middle East) where it represents one of t...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.2021.1894501
更新日期:2021-12-01 00:00:00
abstract::Bluetongue (BT) is an infectious viral disease which affects a wide range of ruminants and was first reported in India in 1964. In view of the absence of comprehensive information on the BT status in India, this study presents the seroprevalence on BT in farm animals of India based-on a systematic review and meta-anal...
journal_title:The veterinary quarterly
pub_type: 杂志文章,meta分析
doi:10.1080/01652176.2020.1810356
更新日期:2020-12-01 00:00:00
abstract::Background: Congenital portosystemic shunts (CPSS) are vascular anomalies, allowing portal blood to bypass the hepatic parenchyma, thereby accumulating toxic substances such as ammonia in the systemic circulation resulting in hepatic encephalopathy.Aim: To evaluate the outcome of non-surgically treated dogs with a CPS...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.2020.1745928
更新日期:2020-12-01 00:00:00
abstract::Gallibacterium anatis is a Gram-negative bacterium of the Pasteurellaceae family that resides normally in the respiratory and reproductive tracts in poultry. It is a major cause of oophoritis, salpingitis, and peritonitis, decreases egg production and mortality in hens thereby severely affecting animal welfare and ove...
journal_title:The veterinary quarterly
pub_type: 杂志文章,评审
doi:10.1080/01652176.2020.1712495
更新日期:2020-12-01 00:00:00
abstract::Wide and discriminate use of antibiotics has resulted in serious biological and ecological concerns, especially the emergence of antibiotic resistance. Probiotics, known as beneficial microbes, are being proposed as an effective and eco-friendly alternative to antibiotics. They were first applied in aquaculture specie...
journal_title:The veterinary quarterly
pub_type: 杂志文章,评审
doi:10.1080/01652176.2016.1172132
更新日期:2016-12-01 00:00:00
abstract::Van Driessche, K., Ducatelle, R., Chiers, K., Van Coster, R. and van der Kolk, J. H. (2015) Ultrastructural Mitochondrial Alterations in Equine Myopathies of Unknown Origin, Veterinary Quarterly, 35(01), pp. 3-9. http://dx.doi.org/10.1080/ 01652176.2015.983681 When the above article was first published online, J. H. v...
journal_title:The veterinary quarterly
pub_type: 已发布勘误
doi:10.1080/01652176.2015.1008273
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Over the past 10 years, an increase in methicillin and multi-drug resistant staphylococcal species has been identified worldwide and anecdotally reported within our veterinary teaching hospital. OBJECTIVE:To determine the methicillin resistance (MR) and multi-drug resistance (MDR) patterns of staphylococcal...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.2013.799792
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Clindamycin is frequently used for the treatment of bacterial pyoderma. OBJECTIVE:To compare the pharmacokinetics of clindamycin in whole skin homogenates of normal dogs when administered orally at two dosage regimens (5.5 mg/kg BW, twice daily and 11 mg/kg BW, once daily). ANIMALS AND METHODS:Skin biopsie...
journal_title:The veterinary quarterly
pub_type: 杂志文章,随机对照试验
doi:10.1080/01652176.2013.772315
更新日期:2013-01-01 00:00:00
abstract::Both spondylosis and diffuse idiopathic skeletal hyperostosis (DISH) are prevalent in humans and are considered distinct entities. Nowadays, the term spondylosis is in the biomedical literature mostly used when also degenerative disc disease is present. In companion animals, many reports on spondylosis, often without ...
journal_title:The veterinary quarterly
pub_type: 杂志文章,评审
doi:10.1080/01652176.2013.770181
更新日期:2013-01-01 00:00:00
abstract::Immune deficiency and altered immunity are among the best characterized and strongest known risk factors of non-Hodgkin lymphomas (NHL). For instance, chronic inflammation or certain disturbances in the immune system are associated with an increased lymphoma risk. Occupational and environmental factors (i.e., dioxin) ...
journal_title:The veterinary quarterly
pub_type: 杂志文章,评审
doi:10.1080/01652176.2012.709362
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Equine inflammatory small bowel disease (ISBD) is an idiopathic pathologic condition seeming to increase in prevalence. OBJECTIVE:To investigate the potential role of gluten in equine ISBD. ANIMALS & METHODS:Antibodies known to be important in the diagnosis of human coeliac disease (CD): IgA antibodies to ...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.2012.675636
更新日期:2012-01-01 00:00:00
abstract::Mycobacterium avium subspecies paratuberculosis is the causative agent of paratuberculosis in cattle which causes a chronic infection of the small intestine. Since the transmission is only partly understood current control programs have been able to only decrease prevalence but not to eradicate disease from a herd. Un...
journal_title:The veterinary quarterly
pub_type: 杂志文章,评审
doi:10.1080/01652176.2012.659870
更新日期:2012-01-01 00:00:00
abstract::Summary After a brief review of the present knowledge about canine viral enteritis, the role played by parvoviral, coronaviral and rotaviral infections in contagious diarrhoea in dogs in the Netherlands is discussed. For this purpose a serologic survey, pathologic findings in dogs, and the demonstration of parvovi...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.1980.9693779
更新日期:1980-10-01 00:00:00
abstract::Summary In this review article, some recent developments in the immunology of parasitic infections are presented. After an introduction in which the major human parasitic infectious diseases, including malaria, african and american trypanosomiasis, leishmaniasis, filariasis an schistosomiasis are mentioned, a descr...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.1980.9693775
更新日期:1980-07-01 00:00:00
abstract::Summary Sera from 683 pigs of 41 swine herds with clinical atrophic rhinitis (A R), from 477 pigs of 37 herds with no A R history, from 267 breeding sows and breeding boars for slaughtering, from 22 boars at an artifical insemination centre, and from 103 SPF pigs were tested for the presence of antibodies to porcine...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.1980.9693760
更新日期:1980-04-01 00:00:00
abstract::Summary Four live virus vaccines against Infectious Bursal Disease (IBD) were studied with regard to their safety, immune response and applicability. None of the vaccines caused clinical symptoms or had an adverse impact on bodyweight. Differences between these vaccins were observed in their effect on the Bursa/ Bod...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.1980.9693757
更新日期:1980-01-01 00:00:00
abstract::Summary To give an impression of the usefulness of indirect haemagglutination (IHA) in the diagnosis of lungworm infections in cattle under practical conditions, five calves vaccinated against Dictyocaulus viviparus and five unvaccinated calves were periodically subjected to clinical, parasitological, and serologica...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.1979.9693747
更新日期:1979-10-01 00:00:00
abstract::Summary Blood lymphocyte and skin fibroblast cultures from cattle with hereditary zinc deficiency (lethal trait A 46) have not revealed unusually large numbers of cells with chromosomal aberrations as reported by Herzog and Höhn (6). ...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.1979.9693733
更新日期:1979-07-01 00:00:00
abstract::Summary Gilts and sows kept under unphysiological commercial conditions may show delayed puberty, delayed estrus postweaning and delayed returns after insemination. It is postulated that in all three manifestations gonadotropic insufficiency is the causative factor, produced by inadequate exteroceptive stimulation, ...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.1979.9693729
更新日期:1979-04-01 00:00:00
abstract:BACKGROUND:Glucocorticoids are suggested to precipitate laminitis and induce insulin resistance in horses. HYPOTHESIS/OBJECTIVES:To assess insulin sensitivity and the basal amount of glucose metabolized in equine pituitary pars intermedia dysfunction (PPID). ANIMALS AND METHODS:The euglycaemic hyperinsulinaemic clamp...
journal_title:The veterinary quarterly
pub_type: 杂志文章
doi:10.1080/01652176.2011.570127
更新日期:2011-03-01 00:00:00