Abstract:
:Melanoma progression is typically depicted as a linear and stepwise process in which metastasis occurs relatively late in disease progression. Significant evidence suggests that in a subset of melanomas, progression is much more complex and less linear in nature. Epidemiologic and experimental observations in melanoma metastasis are reviewed here and are incorporated into a comprehensive model for melanoma metastasis, which takes into account the varied natural history of melanoma formation and progression.
journal_name
Oncogenejournal_title
Oncogeneauthors
Damsky WE,Theodosakis N,Bosenberg Mdoi
10.1038/onc.2013.194subject
Has Abstractpub_date
2014-05-08 00:00:00pages
2413-22issue
19eissn
0950-9232issn
1476-5594pii
onc2013194journal_volume
33pub_type
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