A cost-effectiveness analysis of the prophylaxis versus on-demand regimens in severe hemophilia A patients under 12 years old in southern Iran.

abstract：:Although bone pain is common in multiple myeloma (MM), muscular symptoms, especially myalgias, may be rare. We describe a patient who presented with generalised myopathy and elevated creatine kinase (CK) suggestive of polymyositis. Routine blood tests showed raised viscosity and marked rouleaux formation in the periph...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Islam A,Myers K,Cassidy DM,Ho SF,De Silva M

更新日期：1999-01-01 00:00:00

abstract：:The murine hematopoietic stroma is essential for the homing and the continued replication of hematopoietic stem cells following transplantation and appears to control their lineage proliferation. In our studies it has been found to consist of 3 cell types with differing antigenic displays, growth factor responses and ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Wolf NS

更新日期：1999-01-01 00:00:00

abstract：:Background. Heparin is the most commonly used drug in patients requiring therapeutic anticoagulation. But the use of heparin has serious side effects such as heparin-induced thrombocytopenia (HIT). The diagnosis of HIT is often difficult. This study was designed to test the diagnosis value of 2 laboratory tests: the p...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Rugeri L,Bauters A,Trillot N,Susen S,Decoen C,Watel A,Jude B

更新日期：1999-01-01 00:00:00

abstract：:Historically, the mortality rate of thrombotic thrombocytopenic purpura (TTP) approached 100%. However, by the 1980's, new therapy was instituted with a vast improvement in survival to 90%. The exact pathogenesis of TTP remains elusive. Yet, despite incomplete understanding of the pathophysiology, outcome has improved...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Hong JJ,Kwaan HC

更新日期：2000-01-01 00:00:00

abstract：:Acute myelogenous leukemia is a heterogeneous disease that appears to evade the normal regulatory controls of tumor suppressor genes. Studies in AML have documented mutations in both p53 and Retinoblastoma (Rb) genes, but these mutations are relatively uncommon, especially compared to their mutational frequency in sol...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Stirewalt DL,Radich JP

更新日期：2000-01-01 00:00:00

abstract：:The authors report the case of a 59-year-old woman who developed acute myeloid leukemia nine months after the resolution of systemic sarcoidosis treated by corticosteroid therapy. This rare case poses the questions of the physiopathogenic mechanisms, particularly a granulomatous reaction to leukemic antigens or to cyt...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Alliot C,Barrios M,Franck F

更新日期：2000-01-01 00:00:00

abstract：:Using a factor-dependent cell line MO7ER, which contains a stably transduced human erythropoietin (EPO) receptor gene in human megakaryoblastic cell line MO7e and which resulted in concomitant expression of EPO receptor, c-Mpl and c-Kit, we investigated the biological effects of these cytokines in terms of cell growth...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Miyazawa K,Nishimaki J,Katagiri T,Yaguchi M,Iwase O,Gotoh A,Tauchi T,Kawanishi Y,Toyama K,Ohyashiki K,Ishibashi T,Broxmeyer HE

更新日期：2000-01-01 00:00:00

abstract：:Cutaneous GVHD is histologically similar to eruptions induced by drugs containing a sulfhydryl group. The levels of interleukin-2 and interleukin-2 receptor were determined in a group of patients undergoing bone marrow transplantation (BMT) without graft-versus-host disease or any other complications and in a group wi...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Takatsuka H,Takemoto Y,Yamada S,Mori A,Wada H,Fujimori Y,Okamoto T,Kanamaru A,Kakishita E

更新日期：2002-02-01 00:00:00

abstract：:Cytomegalovirus (CMV)-related deaths and data of clinically evident CMV disease were assessed in a group of 47 individuals given allogeneic non-myeloablative hematopoietic stem cell transplants (NST). IgG anti-CMV antibodies were found in 56% of the donors and 76% of the receptors. Prophylactic ganciclovir was given t...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Ruiz-Argüelles GJ,Gómez-Almaguer D,López-Martínez B,Ponce-De-León S,Cantú-Rodriguez OG,Jaime-Pérez JC

更新日期：2002-04-01 00:00:00

abstract：:Approaches using reduced conditioning regimens have been developed to obtain minimal procedure-related toxicity. Such novel therapeutic options are being explored with good preliminary results concerning feasibility and engraftment. However, many aspects remain under-evaluated and few data are available about immune a...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Mohty M,Gaugler B,Faucher C,Sainty D,Lafage-Pochitaloff M,Vey N,Bouabdallah R,Arnoulet C,Gastaut JA,Viret F,Wolfers J,Maraninchi D,Blaise D,Olive D

更新日期：2002-06-01 00:00:00

abstract：:The development of gastric mucosa-associated lymphoid tissue (MALT) lymphoma depends critically on Helicobacter pylori infection. The bacterial infection stimulates the lymphoma B-cells through both direct (auto-antigen) and indirect (H. pylori specific intra-tumour T-cells) immunological stimulation. It also promotes...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Du MQ

更新日期：2002-12-01 00:00:00

abstract：:An audit of the effect of anticoagulant prophylaxis in acute exacerbations of severe autoimmune haemolysis was undertaken. All cases of this disorder presenting to one institution over a 16 year period were reviewed. There were 28 patients who had a total of thirty six exacerbations of haemolysis. Anticoagulant prophy...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Hendrick AM

更新日期：2003-02-01 00:00:00

abstract：:We report our experience of allogeneic peripheral blood stem cell transplantation using non-myeloablative conditioning regimens delivered and supported on an outpatient basis. A group of 44 patients underwent 47 allograft procedures using peripheral blood stem cells. Approximately one third of the individuals did not ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Ruiz-Argüelles GJ,López-Martínez B,Gómez-Rangel D,Estrada E,Marín-López A,Bravo-Hernández G,Manuel Hernández J

更新日期：2003-06-01 00:00:00

abstract：UNLABELLED:Hepatic veno-occlusive disease (VOD) is a common and potentially fatal complication of high dose chemotherapy with allogeneic/autologous stem cell transplant (SCT). The diagnosis and treatment of hepatic VOD is controversial. Clinical features are non-specific and may be mimicked by a number of other conditi...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Kaleelrahman M,Eaton JD,Leeming D,Bowyer K,Taberner D,Chang J,Scarffe JH,Chopra R

更新日期：2003-04-01 00:00:00

abstract：:Similarities between hepatic graft-versus-host disease (GVHD) and primary biliary cirrhosis (PBC) have been reported recently. To examine this association, we studied 60 patients who underwent allogeneic bone marrow transplantation (BMT) consecutively at a single medical institution.Among the 60 patients, 12 developed...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Wakae T,Takatsuka H,Seto Y,Iwata N,Mori A,Okada M,Fujimori Y,Okamoto T,Kakishita E,Hara H

更新日期：2002-10-01 00:00:00

abstract：:All cases S16 years of age with a histological diagnosis of non-Hodgkin's lymphoma (NHL) and Hodgkin's disease (HD) presented in Scotland between 1 January 1994 and 31 December 1996 were registered prospectively in the Scotland and Newcastle Lymphoma Group database by a process of total registration. The census popula...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Ewing JC,White JM,Rattray A,Lessells A,Mackie MJ

更新日期：2003-08-01 00:00:00

abstract：:We present our recent experience treating five children with severe aplastic anemia (SAA). One patient was transplanted and the remaining 4 patients were treated with immunosuppression of various types and duration. These five cases illustrate the many outstanding points which remain to be clarified regarding the care...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Trigg ME,Bond R,Giri N,Walter AW

更新日期：2003-12-01 00:00:00

abstract：:The case of a patient with the aplastic variant of hairy cell leukaemia, successfully treated with the drug Deoxycoformycin(Pentostatin), is presented. It is very important to be aware of this rare variant of a rare disease so that the right treatment can be offered. ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Ng JP,Nolan B,Chan-Lam D,Coup AJ,McKenna D

更新日期：2002-08-01 00:00:00

abstract：:We describe a patient with chronic myelogenous leukemia who developing severe intestinal bleeding after allogeneic peripheral blood stem cells transplantation (allo-PBSCT). PBSC were obtained from an HLA one-locus mismatch sibling donor. On day 26 after PBSCT, although there was no sign of graft-versus-host disease (G...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Nomura K,Nakao M,Matsumoto Y,Taji S,Yoshida N,Mitsufuji S,Yokota S,Horiike S,Okanoue T,Taniwaki M

更新日期：2004-04-01 00:00:00

abstract：:The Myelodysplastic Syndrome (MDS) comprises a spectrum of hematopoietic stem cell disorders. Identification of additional parameters that might distinguish different risk groups or entities would be useful. Flow cytometric studies have begun to characterize individual or composite immunophenotypic abnormalities as we...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Benesch M,Deeg HJ,Wells D,Loken M

更新日期：2004-06-01 00:00:00

abstract：:Cancer-associated venous thromboembolism is a severe form of paraneoplastic syndrome. It rarely leads to venous gangrene. We report a case who presented with multiple deep venous thrombosis and venous gangrene of the lower extremity. During the follow-up period, the patient developed bilateral cervical and right supra...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Apras S,Elsurer R,Calguneri M,Haznedaroglu IC,Ozbalkan Z,Karakaya G,Coplu L

更新日期：2004-08-01 00:00:00

abstract：:We tested a set of commercially available probes to determine the feasibility and accuracy of FISH in the detection of abnormalities in 13 patients with Chronic Lymphocytic Leukemia (CLL) with a particular aggressive clinical disease. We utilized three different probes for the 13q12-14 region, one for the centromeric ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Gozzetti A,Crupi R,Tozzuoli D,Raspadori D,Forconi F,Lauria F

更新日期：2004-10-01 00:00:00

abstract：:Thalassemia intermedia patients show variable phenotypes. Hydroxyurea (HU) may benefit some of the thalassemia intermedia cases (1), however, the parameters influencing the response to HU have not been reported. In this study, the molecular parameters, alpha-globin and beta-globin genotype and the Xmn I polymorphism, ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Panigrahi I,Dixit A,Arora S,Kabra M,Mahapatra M,Choudhry VP,Saxena R

更新日期：2005-02-01 00:00:00

abstract：:Angiogenesis is the formation of new blood vessels and is controlled by a balance between positive and negative angiogenic regulatory factors. Soluble vascular endothelial growth factor receptors 1,2 (Flt-1, KDR) are the negative counterpoint to the vascular endothelial growth factor (VEGF) signaling pathway, which ha...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Aref S,El Sherbiny M,Goda T,Fouda M,Al Askalany H,Abdalla D

更新日期：2005-04-01 00:00:00

abstract：:Chronic lymphocytic leukemia (CLL) results from the relentless accumulation of small mature, slowly dividing, monoclonal B-lymphocytes. The clinical course is heterogeneous, some patients with aggressive form of the disease progressing rapidly with early death while others exhibit a more stable, possibly, non-progress...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Suresh K,Rodriguez-Lecompte JC,Gauldie J,Foley R

更新日期：2005-06-01 00:00:00

abstract：:Heparin has been the mainstay of treatment and prevention of venous and arterial thromboembolism for many years. Its use, however, is associated with a serious and potentially fatal immunological drug reaction termed heparin-induced thrombocytopenia (HIT). Current treatment consists of discontinuing heparin therapy an...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Kuo KH,Kovacs MJ

更新日期：2005-08-01 00:00:00

abstract：:In the last few years, the field of iron metabolism has exploded with the discovery of many new proteins including ferroportin, hephaestin, hepcidin, duodenal cytochrome b and the topic of this review, divalent metal ion transporter 1 (DMT1). DMT1 functions in transport of ferrous iron, and some, but not all divalent ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Mims MP,Prchal JT

更新日期：2005-08-01 00:00:00

abstract：:At the end of this presentation the audiences should be able to understand the goal of external quality assessment and definitions used to describe similar functions of terminology. Also they had information about overview of interlaboratory method performance studies in Turkey in Hematology. ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Laleli YR,Oktem M

更新日期：2005-01-01 00:00:00

abstract：:Acquired blood coagulation inhibitors are circulating immunoglobulins that neutralize the activity of a specific coagulation protein or accelerate its clearance from the plasma, thus causing a bleeding tendency. In this review, we focus on the nonhemophilic inhibitors of coagulation, i.e. the autoantibodies occurring ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Franchini M,Veneri D

更新日期：2005-12-01 00:00:00

abstract：:The therapeutic approach to patients with autoimmune disorders is in the midst of a dramatic change. Monoclonal antibody technology has allowed us to dissect and now manipulate the human immune system with greater precision. It is now widely recognized that B lymphocytes play a role in the pathogenesis of many autoimm...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Tuscano JM,Martin S,Song K,Wun T

更新日期：2005-12-01 00:00:00