[Chemical and biological evaluation of the effect of plant extracts against Plasmodium berghei].

Abstract:

:Extracts from thirteen species of plants were evaluated by "in vivo" antimalarial test against plasmodium berghei effects. Significant activities were observed in the ethyl acetate and aqueous extracts, elaborated of Cedrela tonduzii leaves, Trichilia havanensis and Trichilia americana barks, Neurolaena lobata and Gliricidia sepium leaves and Duranta repens fruits. Compounds identified include flavanoids, coumarins, mellilotic acid and iridoids which some kind of biodynamic activity has previously been reported. The flavone quercetin 1 purified from C. tonduzii gave strong antimalarial activity, however, its respective glucosides (quercetin 3-glucoside 2 y robinine 7) showed little significant activity.

journal_name

Rev Biol Trop

authors

Castro O,Barrios M,Chinchilla M,Guerrero O

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

361-7

issue

2A

eissn

0034-7744

issn

2215-2075

journal_volume

44

pub_type

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