Isolated cerebral susceptibility artefacts in patients with malignant melanoma: metastasis or not?

Abstract:

OBJECTIVE:While staging patients with malignant melanoma, cerebral susceptibility artefacts on T2*-weighted/susceptibility-weighted imaging (SWI) sequences without a correlate on contrast-enhanced T1-weighted images can be confusing. Without intravenous contrast enhancement, cavernomas, microhaemorrhages and melanin-containing metastases represent possible differential diagnoses for these findings. The purpose of this study was to find out, how often such lesions correspond to metastases. METHODS:Brain MR images (1.5 T) of 408 patients with malignant melanoma but without cerebral metastases in the initial staging by MRI were reviewed retrospectively. Eighteen patients (5 female, 13 male) with malignant melanoma and signal intensity loss on T2*/SWI were included in our study. The average observation period was 19.6 months (6-46 months, 2006-2009). RESULTS:In each of these 18 patients between one and seven hypointense lesions on T2*/SWI were found. None of these lesions developed into metastasis. CONCLUSION:Focal areas of susceptibility artefacts in the brain parenchyma without corresponding abnormalities in contrast-enhanced T1 weighted images are unlikely to represent brain metastases. KEY POINTS:• In melanoma patients early diagnosis of metastatic brain lesions is mandatory. • Melanin content and haemorrhage are potential reasons for MRI characteristics of melanoma metastases. • Susceptibility-weighted MRI visualises melanin and blood products. • Isolated cerebral susceptibility artefacts do not convert into melanoma metastases. • SWI/T2* sequences cannot replace Gd-enhanced sequences.

journal_name

Eur Radiol

journal_title

European radiology

authors

Gramsch C,Göricke SL,Behrens F,Zimmer L,Schadendorf D,Krasny A,Forsting M,Schlamann MU

doi

10.1007/s00330-013-2857-3

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

2622-7

issue

9

eissn

0938-7994

issn

1432-1084

journal_volume

23

pub_type

杂志文章
  • A "one-stop-shop" 4D CTA protocol using 320-row CT for advanced imaging in acute ischemic stroke: a technical note.

    abstract::This technical note describes a novel CT scan protocol that includes a non-enhanced CT, dynamic CTA, and perfusion of the whole brain and CTA of the carotid arteries using a 320-row area detector CT scanner, with a unique contrast injection and acceptable radiation exposure dose in patients presenting with acute ische...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-019-06041-x

    authors: Ognard J,Dissaux B,Haioun K,Nonent M,Gentric JC,Ben Salem D

    更新日期:2019-09-01 00:00:00

  • Precision of tibial cartilage morphometry with a coronal water-excitation MR sequence.

    abstract::The aim of this study was to analyze the precision of tibial cartilage morphometry, by using a fast, coronal water-excitation sequence with high spatial resolution, to compare the reproducibility of 3D thickness vs volume estimates, and to test the technique in patients with severe osteoarthritis. The tibiae of 8 heal...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300050047

    authors: Hyhlik-Dürr A,Faber S,Burgkart R,Stammberger T,Maag KP,Englmeier KH,Reiser M,Eckstein F

    更新日期:2000-01-01 00:00:00

  • Metal artifact reduction by dual energy computed tomography using monoenergetic extrapolation.

    abstract:OBJECTIVE:The aim of the study was to assess the performance and diagnostic value of a dual energy CT approach to reduce metal artefacts in subjects with metallic implants. METHODS:31 patients were examined in the area of their metallic implants using a dual energy CT protocol (filtered 140 kVp and 100 kVp spectrum, t...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-011-2062-1

    authors: Bamberg F,Dierks A,Nikolaou K,Reiser MF,Becker CR,Johnson TR

    更新日期:2011-07-01 00:00:00

  • Extra-articular soft tissue ganglion cyst around the knee: focus on the associated findings.

    abstract::The aim of this study was to evaluate MR imaging findings of the associated findings in surrounding tissues of the extra-articular soft tissue ganglion cysts around the knee. We retrospectively reviewed MR images of 30 patients who had surgically confirmed extra-articular soft tissue ganglion cysts around the knee wit...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-003-1969-6

    authors: Kim JY,Jung SA,Sung MS,Park YH,Kang YK

    更新日期:2004-01-01 00:00:00

  • Relaxation-compensated amide proton transfer (APT) MRI signal intensity is associated with survival and progression in high-grade glioma patients.

    abstract:OBJECTIVES:The purpose of this study was to investigate the association of relaxation-compensated chemical exchange saturation transfer (CEST) MRI with overall survival (OS) and progression-free survival (PFS) in newly diagnosed high-grade glioma (HGG) patients. METHODS:Twenty-six patients with newly diagnosed high-gr...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-019-06066-2

    authors: Paech D,Dreher C,Regnery S,Meissner JE,Goerke S,Windschuh J,Oberhollenzer J,Schultheiss M,Deike-Hofmann K,Bickelhaupt S,Radbruch A,Zaiss M,Unterberg A,Wick W,Bendszus M,Bachert P,Ladd ME,Schlemmer HP

    更新日期:2019-09-01 00:00:00

  • Hepatobiliary contrast agents for contrast-enhanced MRI of the liver: properties, clinical development and applications.

    abstract::Hepatobiliary contrast agents with uptake into hepatocytes followed by variable biliary excretion represent a unique class of cell-specific MR contrast agents. Two hepatobiliary contrast agents, mangafodipir trisodium and gadobenate dimeglumine, are already clinically approved. A third hepatobiliary contrast agent, Gd...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00330-004-2236-1

    authors: Reimer P,Schneider G,Schima W

    更新日期:2004-04-01 00:00:00

  • Differentiation of myocardial ischemia and infarction assessed by dynamic computed tomography perfusion imaging and comparison with cardiac magnetic resonance and single-photon emission computed tomography.

    abstract:OBJECTIVES:To evaluate the feasibility of myocardial blood flow (MBF) by computed tomography from dynamic CT perfusion (CTP) for detecting myocardial ischemia and infarction assessed by cardiac magnetic resonance (CMR) or single-photon emission computed tomography (SPECT). METHODS:Fifty-three patients who underwent st...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-016-4238-1

    authors: Tanabe Y,Kido T,Uetani T,Kurata A,Kono T,Ogimoto A,Miyagawa M,Soma T,Murase K,Iwaki H,Mochizuki T

    更新日期:2016-11-01 00:00:00

  • Integrated diagnostic imaging of primary thoracic rhabdomyosarcoma.

    abstract::We report a rare case of primary thoracic rhabdomyosarcoma in a girl who was referred with acute chest pain, hacking cough, and wheezing. A chest X-ray revealed a complete opacity of the right hemithorax. Ultrasound revealed a right-sided pleural effusion and a solid mass above the liver dome, suggesting a neoplastic ...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300000507

    authors: Almberger M,Iannicelli E,Matrunola M,Schiavetti A,Capocaccia P

    更新日期:2001-01-01 00:00:00

  • Combined transcatheter arterial chemoembolization and percutaneous ethanol injection for the treatment of large hepatocellular carcinoma: local therapeutic effect and long-term survival rate.

    abstract::The aim of our study was to investigate local therapeutic effects and long-term results of combined transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) in the treatment of large hepatocellular carcinoma (HCC). Eight-six patients (67 males and 19 females, age range 48-75 years, mean...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300050409

    authors: Lencioni R,Paolicchi A,Moretti M,Pinto F,Armillotta N,Di Giulio M,Cicorelli A,Donati F,Cioni D,Bartolozzi C

    更新日期:1998-01-01 00:00:00

  • Time-resolved computed tomography of the liver: retrospective, multi-phase image reconstruction derived from volumetric perfusion imaging.

    abstract:OBJECTIVE:To assess feasibility and image quality (IQ) of a new post-processing algorithm for retrospective extraction of an optimised multi-phase CT (time-resolved CT) of the liver from volumetric perfusion imaging. METHODS:Sixteen patients underwent clinically indicated perfusion CT using 4D spiral mode of dual-sour...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-013-2992-x

    authors: Fischer MA,Leidner B,Kartalis N,Svensson A,Aspelin P,Albiin N,Brismar TB

    更新日期:2014-01-01 00:00:00

  • Diffusion-weighted imaging or dynamic contrast-enhanced curve: a retrospective analysis of contrast-enhanced magnetic resonance imaging-based differential diagnoses of benign and malignant breast lesions.

    abstract:OBJECTIVE:To compare the diagnostic performance of models based on a combination of contrast-enhanced (CE) magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI) or time-intensity curves (TIC) in diagnosing malignancies of breast lesions. METHODS:A double-blind retrospective study was conducted in 328 ...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-06883-w

    authors: Yang X,Dong M,Li S,Chai R,Zhang Z,Li N,Zhang L

    更新日期:2020-09-01 00:00:00

  • MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas.

    abstract:OBJECTIVES:To assess the combined role of tumor vascularity, estimated from perfusion MRI, and MGMT methylation status on overall survival (OS) in patients with glioblastoma. METHODS:A multicentric international dataset including 96 patients from NCT03439332 clinical study were used to study the prognostic relationshi...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-07297-4

    authors: Fuster-Garcia E,Lorente Estellés D,Álvarez-Torres MDM,Juan-Albarracín J,Chelebian E,Rovira A,Acosta CA,Pineda J,Oleaga L,Mollá-Olmos E,Filice S,Due-Tønnessen P,Meling TR,Emblem KE,García-Gómez JM

    更新日期:2020-10-01 00:00:00

  • Contrast enhancement for the abdomen and pelvis.

    abstract::A "quadraphasic" imaging technique is described for imaging malignancies of the abdomen (liver, kidneys and pancreas). With this technique images are acquired during four different phases relative to the administration of contrast agent: pre-contrast (baseline), during the capillary (arterial, pre-sinusoidal) phase, d...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/pl00006899

    authors: Mitchell DG

    更新日期:1997-01-01 00:00:00

  • Correlation of patient survival with clinical tumor measurements in malignant pleural mesothelioma.

    abstract:OBJECTIVES:To evaluate differences in the tumor response classifications that result from clinical measurements and to compare these response classifications with overall survival for patients with malignant pleural mesothelioma (MPM). METHODS:One hundred thirty-one computed tomography (CT) scans were collected from 4...

    journal_title:European radiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00330-018-5887-z

    authors: Li F,Ahmad M,Qayyum F,Straus CM,MacMahon H,Kindler H,Armato SG 3rd

    更新日期:2019-06-01 00:00:00

  • Development of an online, publicly accessible naive Bayesian decision support tool for mammographic mass lesions based on the American College of Radiology (ACR) BI-RADS lexicon.

    abstract:PURPOSE:To develop and validate a decision support tool for mammographic mass lesions based on a standardized descriptor terminology (BI-RADS lexicon) to reduce variability of practice. MATERIALS AND METHODS:We used separate training data (1,276 lesions, 138 malignant) and validation data (1,177 lesions, 175 malignant...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-014-3570-6

    authors: Benndorf M,Kotter E,Langer M,Herda C,Wu Y,Burnside ES

    更新日期:2015-06-01 00:00:00

  • Breast MR biopsy: Pathological and radiological correlation.

    abstract:PURPOSE:To identify pathological features for sample analysis of magnetic resonance imaging-guided vaccum-assisted breast biopsy (MRIgVaBB) to optimize radio pathological correlation and identify discordant benign result. MATERIAL AND METHODS:Databases of two centres were queried to identify MRIgVaBB performed between...

    journal_title:European radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00330-015-4071-y

    authors: Dratwa C,Jalaguier-Coudray A,Thomassin-Piana J,Gonin J,Chopier J,Antoine M,Trop I,Darai E,Thomassin-Naggara I

    更新日期:2016-08-01 00:00:00

  • Future prospects for SonoVue and CPS.

    abstract::Though long considered unlikely because of the resonance pattern of agents such as SonoVue, high frequency applications for small parts and intracavitary applications now seem very promising. Excellent non-linear signals can be obtained at 7 MHz and higher using recently developed CPS software, and preliminary results...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s10406-004-0084-3

    authors: Cosgrove D

    更新日期:2004-10-01 00:00:00

  • Association of "initial CT" findings with mortality in older patients with coronavirus disease 2019 (COVID-19).

    abstract:OBJECTIVES:To investigate the association of chest CT findings with mortality in clinical management of older patients. METHODS:From January 21 to February 14, 2020, 98 older patients (≥ 60 years) who had undergone chest CT scans ("initial CT") on admission were enrolled. Manifestation and CT score were compared betwe...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-06969-5

    authors: Li Y,Yang Z,Ai T,Wu S,Xia L

    更新日期:2020-11-01 00:00:00

  • Imaging of diffuse esophageal leiomyomatosis: two case reports and review of the literature.

    abstract::Diffuse esophageal leiomyomatosis is a rare disorder which may be found in association with leiomyomas in other locations or with other disorders. We report two cases in men, one with associated tracheobronchial involvement, which illustrate the value of imaging in differentiating this entity from other causes of dysp...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s003300050019

    authors: Sans N,Galy-Fourcade D,Bloom E,Pradère B,Chiavassa H,Jarlaud T,Queralto M,Giron J,Gouzi JL,Railhac JJ

    更新日期:2000-01-01 00:00:00

  • Detection of intralabyrinthine abnormalities using post-contrast delayed 3D-FLAIR MRI sequences in patients with acute vestibular syndrome.

    abstract:PURPOSE:3D-FLAIR sequences with delayed acquisition after contrast medium injection have demonstrated new insights into blood-labyrinthine barrier (BLB) abnormalities in various diseases. The aim of this study was to assess the BLB in patients referred with unilateral acute vestibular syndrome (UAVS). MATERIALS AND ME...

    journal_title:European radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00330-018-5825-0

    authors: Eliezer M,Maquet C,Horion J,Gillibert A,Toupet M,Bolognini B,Magne N,Kahn L,Hautefort C,Attyé A

    更新日期:2019-06-01 00:00:00

  • CT appearance of the larynx after conservative and radical surgery for carcinomas.

    abstract::The purpose of this study was to evaluate the normal CT appearance of the larynx after conservative and radical surgery. Postoperative (conservative surgery n = 52, radical surgery n = 21) CT examinations of 73 patients suspected of local/regional recurrence (n = 53) or asymptomatic (n = 20) were retrospectively analy...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300050179

    authors: Maroldi R,Battaglia G,Nicolai P,Maculotti P,Cappiello J,Cabassa P,Farina D,Chiesa A

    更新日期:1997-01-01 00:00:00

  • CT assessment-based direct surgical resection of part-solid nodules with solid component larger than 5 mm without preoperative biopsy: experience at a single tertiary hospital.

    abstract:OBJECTIVES:To retrospectively evaluate the feasibility of CT assessment-based direct surgical resection of part-solid nodules (PSNs) with solid components > 5 mm without preoperative percutaneous transthoracic needle biopsies (PTNBs). METHODS:From January 2009-December 2014, 85 PSNs with solid components > 5 mm on CT ...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-017-4917-6

    authors: Lee SM,Park CM,Song YS,Kim H,Kim YT,Park YS,Goo JM

    更新日期:2017-12-01 00:00:00

  • Serial changes of CT findings in patients with chronic hypersensitivity pneumonitis: imaging trajectories and predictors of fibrotic progression and acute exacerbation.

    abstract:OBJECTIVES:To evaluate the longitudinal changes of chest CT findings in patients with chronic hypersensitivity pneumonitis (HP) and identify risk factors for fibrotic progression and acute exacerbation (AE). METHODS:This retrospective study included patients with chronic HP with follow-up CT. Baseline and serial follo...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-07469-2

    authors: Choe J,Chae EJ,Kim YJ,Do KH,Song JS,Song JW

    更新日期:2020-11-25 00:00:00

  • Lumbar spine radiology: analysis of the posteroanterior projection.

    abstract::The use of the posteroanterior (PA) technique as a means of dose reduction has been used effectively in radiology departments for chest and abdominal examinations. The aim of this investigation was to establish if the PA lumbar spine projection offers any advantages over the traditional anteroposterior (AP) view in te...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003309900272

    authors: Brennan PC,Madigan E

    更新日期:2000-01-01 00:00:00

  • The effect of four-phasic versus three-phasic contrast media injection protocols on extravasation rate in coronary CT angiography: a randomized controlled trial.

    abstract:OBJECTIVES:Contrast media (CM) extravasation is a well-known complication of CT angiography (CTA). Our prospective randomized control study aimed to assess whether a four-phasic CM administration protocol reduces the risk of extravasation compared to the routinely used three-phasic protocol in coronary CTA. METHODS:Pa...

    journal_title:European radiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00330-017-4866-0

    authors: Karády J,Panajotu A,Kolossváry M,Szilveszter B,Jermendy ÁL,Bartykowszki A,Károlyi M,Celeng C,Merkely B,Maurovich-Horvat P

    更新日期:2017-11-01 00:00:00

  • Magnetic resonance imaging of the fetal lung: a pictorial essay.

    abstract::Ultrasound, which is now a widely available and generally accepted, low-cost technique with real-time properties, is the screening investigation of choice in fetal medicine. However, enthusiasm for fetal prenatal magnetic resonance imaging (MRI) is rising, because of the absence of known biological risks, the increasi...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-008-0877-1

    authors: Cannie M,Jani J,De Keyzer F,Van Kerkhove F,Meersschaert J,Lewi L,Deprest J,Dymarkowski S

    更新日期:2008-07-01 00:00:00

  • Bag-of-features-based radiomics for differentiation of ocular adnexal lymphoma and idiopathic orbital inflammation from contrast-enhanced MRI.

    abstract:OBJECTIVES:To evaluate the effectiveness of bag-of-features (BOF)-based radiomics for differentiating ocular adnexal lymphoma (OAL) and idiopathic orbital inflammation (IOI) from contrast-enhanced MRI (CE-MRI). METHODS:Fifty-six patients with pathologically confirmed IOI (28 patients) and OAL (28 patients) were random...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-07110-2

    authors: Hou Y,Xie X,Chen J,Lv P,Jiang S,He X,Yang L,Zhao F

    更新日期:2021-01-01 00:00:00

  • Correction to: Radiomics on multi-modalities MR sequences can subtype patients with non-metastatic nasopharyngeal carcinoma (NPC) into distinct survival subgroups.

    abstract::The original version of this article, published on 14 March 2019, unfortunately contained a mistake. ...

    journal_title:European radiology

    pub_type: 已发布勘误

    doi:10.1007/s00330-019-06184-x

    authors: Zhuo EH,Zhang WJ,Li HJ,Zhang GY,Jing BZ,Zhou J,Cui CY,Chen MY,Sun Y,Liu LZ,Cai HM

    更新日期:2019-07-01 00:00:00

  • CT-guided core-needle biopsy in the diagnosis of mediastinal lymphoma.

    abstract::The advent of radiologic guidance techniques for percutaneous biopsy has changed the approach to the routine diagnosis of mediastinal lymphoma. The aim of the present study was to evaluate the diagnostic accuracy of CT-guided percutaneous core-needle biopsy (PCNB) in the clinical management of patients with mediastina...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300050991

    authors: Sklair-Levy M,Polliack A,Shaham D,Applbaum YH,Gillis S,Ben-Yehuda D,Sherman Y,Libson E

    更新日期:2000-01-01 00:00:00

  • Classification of hypervascularized lesions in CE MR imaging of the breast.

    abstract::The purpose of this paper is to define and evaluate a classification category for contrast-enhanced (CE) MR imaging of the breast based on the BI-RADS mammographic categories of the American College of Radiology. Using five evaluation criteria for MR findings (initial signal increase, post-initial signal behavior, sha...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-001-1213-1

    authors: Baum F,Fischer U,Vosshenrich R,Grabbe E

    更新日期:2002-05-01 00:00:00