Abstract:
:Parallel to an international Pilot Ring Test to standardize a mutigeneration test protocol with the protozoon Tetrahymena pyriformis supplementary investigations were made. Effects on growth rate and 46 h population density were measured using an extended set of 12 chemicals, a further Tetrahymena-species (T. thermophila) and 4 different media (axenic and bacteria based). Results are compared for sensitivity with effects on additional end points (chemosensory response, respiration and vitality). Both species exhibit similar sensitivity towards the chemicals. In some cases the media composition influenced the toxic potential of chemicals. Both growth parameters proved to be a sensitive integral end point for toxicological studies, confirming the one point, photometric measurement of population density after 46 hours in axenic (preferably proteose peptone-) medium an obvious choice for a standard test procedure.
journal_name
Chemospherejournal_title
Chemosphereauthors
Pauli W,Berger Sdoi
10.1016/s0045-6535(97)00171-9subject
Has Abstractpub_date
1997-09-01 00:00:00pages
1043-52issue
5eissn
0045-6535issn
1879-1298pii
S0045653597001719journal_volume
35pub_type
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