Can dietary interventions change diet and cardiovascular risk factors? A meta-analysis of randomized controlled trials.

Abstract:

OBJECTIVES:This study evaluated the effectiveness of dietary advice in primary prevention of chronic disease. METHODS:A meta-analysis was conducted of 17 randomized controlled trials of dietary behavior interventions of at least 3 months' duration. Results were analyzed as changes in reported dietary fat intakes and biomedical measures (serum cholesterol, urinary sodium, systolic and diastolic blood pressure) in the intervention group minus changes in the control group at 3 to 6 months and 9 to 18 months of follow-up. RESULTS:After 3 to 6 months, mean net changes in each of the five outcomes favored intervention. For dietary fat as a percentage of food energy, the change was -2.5% (95% confidence interval [CI] = -3.9%, -1.1%). Mean net changes over 9 to 18 months were as follows: serum cholesterol, -0.22 (95% CI = -0.39, -0.05) mmol/L; urinary sodium, -45.0 (95% CI = -57.1, -32.8) mmol/24 hours; systolic blood pressure, -1.9 (95% CI = -3.0, 0.8) mm Hg; and diastolic blood pressure, -1.2 (95% CI = -2.6, 0.2) mm Hg. CONCLUSIONS:Individual dietary interventions in primary prevention can achieve modest improvements in diet and cardiovascular disease risk status that are maintained for 9 to 18 months.

journal_name

Am J Public Health

authors

Brunner E,White I,Thorogood M,Bristow A,Curle D,Marmot M

doi

10.2105/ajph.87.9.1415

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

1415-22

issue

9

eissn

0090-0036

issn

1541-0048

journal_volume

87

pub_type

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