Contrasting genomic variability between clones from field isolates and laboratory populations of Schistosoma mansoni.

abstract：:Tissue invasion and pathology by Trypanosoma cruzi result from an interaction between parasite virulence and host immunity. Successive in vivo generations of the parasite select populations with increasing ability to invade the host. Conversely, prolonged in vitro selection of the parasite produces attenuated sublines...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Basombrío MA,Segura MA,Gómez L,Padilla M

更新日期：2000-01-01 00:00:00

abstract：:The global emergence and spread of malaria parasites resistant to antimalarial drugs is the major problem in malaria control. The genetic basis of the parasite's resistance to the antimalarial drug chloroquine (CQ) is well-documented, allowing for the analysis of field isolates of malaria parasites to address evolutio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sutar SK,Gupta B,Ranjit M,Kar SK,Das A

更新日期：2011-02-01 00:00:00

abstract：:Acute Chagas disease (ACD) has a distinct epidemiological profile in the Amazon Region, with cases and outbreaks of Trypanosoma cruzi infection being possibly related to the ingestion of contaminated food. Data on ACD in the state of Pará retrieved from 2000 to 2016 from the Brazilian Notifiable Diseases Information S...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos VRCD,Meis J,Savino W,Andrade JAA,Vieira JRDS,Coura JR,Junqueira ACV

更新日期：2018-01-01 00:00:00

abstract：:Angiotensin II (AII), a product of rennin-angiotensin system, exerts an important role on the function of immune system cells. In this study, the effect of AII on the phagocytic activity of mouse peritoneal macrophages was assessed. Mice peritoneal macrophages were cultured for 48 h and the influence of different conc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Belline P,da Melo PS,Haun M,Palhares FB,Boer PA,Gontijo JA,Figueiredo JF

更新日期：2004-03-01 00:00:00

abstract：:Two new species of the Culicoides paraensis species group, C. diversus Felippe-Bauer and C. peruvianus Felippe-Bauer, are described and illustrated based on female specimens from Amazonian region of Peru. A systematic key, table with numerical characters of females, and distribution of species of the C. paraensis grou...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Felippe-Bauer ML,Cáceres AG,Silva CS,Valderrama-Bazan W,Gonzales-Perez A

更新日期：2003-12-01 00:00:00

abstract：:In the present study, some morphological structures of antennae, maxillary palps and caudal setae of fourth instar larvae of laboratory-reared phlebotomine sand flies (Lutzomyia longipalpis, L. migonei, L. evandroi, L. lenti, L. sericea, L. whitmani and L. intermedia) of the State of Ceará, Brazil, were examined under...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pessoa FA,Guerra de Queiroz R,Ward RD

更新日期：2001-11-01 00:00:00

abstract：:There is a general consensus that during chronic Trypanosoma cruzi infection, the host immune system induces complex processes to ensure the control of parasite growth while preserving the potential to mount and maintain a life-long controlled humoral and cellular immune response against the invading pathogen. This re...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sathler-Avelar R,Vitelli-Avelar DM,Teixeira-Carvalho A,Martins-Filho OA

更新日期：2009-07-01 00:00:00

abstract：:The present report describes an alternative method for in vitro detection of HIV-1-specific antibody secretion in 24h of culture employing as stimulant of peripheral blood mononuclear cells the disrupted inactivated whole virus adsorbed onto microwells in a commercial ELISA kit plates. The results obtained from this t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Caterino-de-Araujo A

更新日期：1992-04-01 00:00:00

abstract：:Although vaccines are the best means of protection against influenza, neuraminidase inhibitors are currently the main antiviral treatment available to control severe influenza cases. One of the most frequent substitutions in the neuraminidase (NA) protein of influenza A(H3N2) viruses during or soon after oseltamivir a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pontoriero A,Avaro M,Benedetti E,Russo M,Czech A,Periolo N,Campos A,Zamora A,Baumeister E

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Dengue virus (DENV) has circulated in Brazil for over 30 years. During this time, one serotype has cyclically replaced the other, until recently, when all four distinct serotypes began to circulate together. Persistent circulation of DENV for long time periods makes sequential infections throughout a person'...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira RA,de Oliveira-Filho EF,Fernandes AI,Brito CA,Marques ET,Tenório MC,Gil LH

更新日期：2019-01-01 00:00:00

abstract：:Data analysis, presentation and distribution is of utmost importance to a genome project. A public domain software, ACeDB, has been chosen as the common basis for parasite genome databases, and a first release of TcruziDB, the Trypanosoma cruzi genome database, is available by ftp from ftp://iris.dbbm.fiocruz.br/pub/g...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Degrave W,de Miranda AB,Amorim A,Brandão A,Aslett M,Vandeyar M

更新日期：1997-11-01 00:00:00

abstract：:Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum malaria that continues to be a major global health problem. Brain vascular dysfunction is a main factor underlying the pathogenesis of CM and can be a target for the development of adjuvant therapies for the disease. Vascular occlusion b...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Carvalho LJ,Moreira Ada S,Daniel-Ribeiro CT,Martins YC

更新日期：2014-08-01 00:00:00

abstract：:We present herein an improved assay for detecting the presence of extracellular proteases from microorganisms on agar plates. Using different substrates (gelatin, BSA, hemoglobin) incorporated into the agar and varying the culture medium composition, we were able to detect proteolytic activities from Pseudomonas aerug...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vermelho AB,Meirelles MN,Lopes A,Petinate SD,Chaia AA,Branquinha MH

更新日期：1996-11-01 00:00:00

abstract：:The diagnosis of tick-borne diseases such as babesiosis still depends on observing the parasite in the infected erythrocyte. Microscopic observation is tedious and often problematic in both early and carrier infections. Better diagnostic methods are needed to prevent clinical disease, especially when susceptible cattl...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Wagner G,Cruz D,Holman P,Waghela S,Perrone J,Shompole S,Rurangirwa F

更新日期：1992-01-01 00:00:00

abstract：:A comparative study was undertaken on the immunogenic properties of 63kDa glycoproteins obtained from five different strains/species of Leishmania and assessed in C57BL/10 mice. The humoral immune response was assessed by ELISA against the five different antigens of the immunized animals. The cellular immune response ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Dabés Guimarães TM,de Toledo VD,da Costa CA,da Costa RT,Genaro O,Williams P,Mayrink W

更新日期：1996-01-01 00:00:00

abstract：:The aim of this study was to test if serological distinction between patients with active and inactive neurocysticercosis (NCC), could be accomplished by the recognition of immunodominant peptides in total saline antigenic extract of Taenia solium metacestodes by IgG antibody in cerebrospinal fluid (CSF) and serum pai...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barcelos IS,Moura LP,Costa VP,Ferreira MS,Costa-Cruz JM

更新日期：2007-09-01 00:00:00

abstract：:Leptoconops nosopheris sp. n. (Diptera: Ceratopogonidae) is described from a blood-filled female biting midge in Early Cretaceous Burmese amber. The new species is characterized by a very elongate terminal flagellomere, elongate cerci, and an indistinct spur on the metatibia. This biting midge contained digenetic tryp...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Poinar G Jr

更新日期：2008-08-01 00:00:00

abstract：:The Brazilian variant of human immunodeficiency virus type 1 (HIV-1) subtype B, (serotype B"-GWGR), has a tryptophan replacing the proline in position 328 the HIV-1 envelope. A longer median time period from infection to acquired immunodeficiency syndrome (AIDS) for serotype B (B"-GWGR) infected subjects compared to t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Casseb J,Montanheiro P,Komninakis S,Brito A,Duarte AJ

更新日期：2004-02-01 00:00:00

abstract：:Schistosomiasis in America with the exception of Brazil, behaves as a chronic mild disease with few clinical manifestations due to low parasite burden. These features restrict the clinical and parasitological diagnosis. The most commonly used stool examination method, Kato-Katz, becomes insensitive when the majority o...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Noya BA,Noya O,Balzan C,Cesari IM

更新日期：1992-01-01 00:00:00

abstract：:Theoretically, serological assays with affinity purified marker antigens can allow strain-specific diagnosis even when parasites cannot be retrieved from an infected host. A Trypanosoma cruzi antigen was purified by affinity chromatography using a zymodeme (Z) 2 specific monoclonal antibody (2E2C11). An indirect enzym...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Schechter M

更新日期：1987-01-01 00:00:00

abstract：:A major advance in our understanding of the natural history of Schistosoma haematobium-related morbidity has come through the introduction of the portable ultrasound machines for non-invasive examination of the kidneys and bladder. With the use of generators or battery packs to supply power in non-clinical field setti...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： King CH

更新日期：2002-01-01 00:00:00

abstract：:Schistosoma mansoni is one of the three main causative agents of human schistosomiasis, a major health problem with a vast socio-economic impact. Recent advances in the proteomic analysis of schistosomes have revealed that peptidases are the main virulence factors involved in the pathogenesis of this disease. In this ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva LL,Marcet-Houben M,Zerlotini A,Gabaldón T,Oliveira G,Nahum LA

更新日期：2011-11-01 00:00:00

abstract：:Toxocara cati is a common feline parasite transmitted by the ingestion of embryonated eggs, by the transmammary route or by predation of paratenic hosts harbouring third-stage larvae in their bodies. In the present study, the larval distribution of T. cati in tissues and organs of Rattus norvegicus experimentally infe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos SV,Lescano SZ,Castro JM,Chieffi PP

更新日期：2009-09-01 00:00:00

abstract：:In Brazil, carbapenem-resistant Pseudomonas aeruginosa isolates are closely related to the São Paulo metallo-β-lactamase (SPM) Brazilian clone. In this study, imipenem-resistant isolates were divided in two sets, 2002/2003 and 2008/2009, analysed by pulsed field gel electrophoresis and tested for the Ambler class B me...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cavalcanti FL,Almeida AC,Vilela MA,Morais MM,Morais Junior MA

更新日期：2012-05-01 00:00:00

abstract：:This article presents an overview of the currently available drugs nifurtimox (NFX) and benznidazole (BZN) used against Trypanosoma cruzi, the aetiological agent of Chagas disease; herein we discuss their limitations along with potential alternatives with a focus on ergosterol biosynthesis inhibitors (EBI). These comp...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Urbina JA

更新日期：2009-07-01 00:00:00

abstract：:To study changes in survival, in biological activities and behavior of planorbids submitted to increased hydrostatic pressure, we developed a technique using two transparent chambers and a hydraulic piston. The apparatus permitted renewal of the liquid medium without substantial variations in pressure, thus eliminatin...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Jurberg P,Soares MS,Mascitelli AC,Favre TC,Barbosa JV

更新日期：1988-01-01 00:00:00

abstract：:Maternal malnutrition during the lactation period in early development may have long-term programming effects on adult offspring. We evaluated the combined effects of parasitological behaviour and histopathological features and malnutrition during lactation. Lactating mice and their pups were divided into a control gr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Corrêa CL,Lisboa PC,Oliveira Ed,Moura EG,Oliveira RM,Gomes AC,Machado-Silva JR

更新日期：2011-08-01 00:00:00

abstract：:Genetic typing of pathogenic agents and of vectors has known impressive developments in the last 10 years, thanks to the progresses of molecular biology, and to the contribution of the concepts of evolutionary genetics. Moreover, we know more and more on the genetic susceptibility of man to infectious diseases. I prop...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Tibayrenc M

更新日期：1998-09-01 00:00:00

abstract：:The aim of this study was to determine the incidence of congenital toxoplasmosis (CT) and to assess the performances of prenatal and neonatal diagnoses. From 1994-2005, in Toulouse University Hospital, France, amniocentesis was performed on 352 pregnant women who were infected during pregnancy. All women were treated ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bessières MH,Berrebi A,Cassaing S,Fillaux J,Cambus JP,Berry A,Assouline C,Ayoubi JM,Magnaval JF

更新日期：2009-03-01 00:00:00

abstract：:The mechanisms that facilitate the adaptation of Trypanosoma cruzi to two distinct hosts, insect and vertebrate, are poorly understood, in part due to the limited ability to perform gene disruption studies by homologous recombination. This report describes a developmentally-defective phenotype that resulted from integ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Zacks MA

更新日期：2007-02-01 00:00:00