Antibacterial Activity of Mangrove Leaf Extracts against Human Pathogens.

Abstract:

:The antibacterial activity of leaf extract of mangroves, namely, Rhizophora mucronata, Sonneratia alba and Exoecaria agallocha from Chorao island, Goa was investigated against human bacterial pathogens Staphylococcus aureus, Streptococcus sp., Salmonella typhi, Proteus vulgaris and Proteus mirabilis. As compared to aqueous, ethanol extract showed broad-spectrum activity. The multidrug-resistant (MDR) bacteria Salmonella typhi was inhibited by the ethanol extract of S. alba leaf whereas the other two resistant bacteria Staphylococcus aureus and Streptococcus sp. were inhibited by the ethanol extract of leaves of all the species. The aqueous extract of S. alba and E. agallocha showed their activity against P. vulgaris and P. mirabilis, respectively. Phytochemical analysis revealed the presence of saponins, glycosides, tannins, flavonoids, phenol and volatile oils in the leaves of mangroves. Further studies using different solvents for extraction are necessary to confirm that mangroves are a better source for the development of novel antibiotics.

journal_name

Indian J Pharm Sci

authors

Sahoo G,Mulla NS,Ansari ZA,Mohandass C

doi

10.4103/0250-474X.107068

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

348-51

issue

4

eissn

0250-474X

issn

1998-3743

pii

IJPhS-74-348

journal_volume

74

pub_type

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