Abstract:
:The antibacterial activity of leaf extract of mangroves, namely, Rhizophora mucronata, Sonneratia alba and Exoecaria agallocha from Chorao island, Goa was investigated against human bacterial pathogens Staphylococcus aureus, Streptococcus sp., Salmonella typhi, Proteus vulgaris and Proteus mirabilis. As compared to aqueous, ethanol extract showed broad-spectrum activity. The multidrug-resistant (MDR) bacteria Salmonella typhi was inhibited by the ethanol extract of S. alba leaf whereas the other two resistant bacteria Staphylococcus aureus and Streptococcus sp. were inhibited by the ethanol extract of leaves of all the species. The aqueous extract of S. alba and E. agallocha showed their activity against P. vulgaris and P. mirabilis, respectively. Phytochemical analysis revealed the presence of saponins, glycosides, tannins, flavonoids, phenol and volatile oils in the leaves of mangroves. Further studies using different solvents for extraction are necessary to confirm that mangroves are a better source for the development of novel antibiotics.
journal_name
Indian J Pharm Scijournal_title
Indian journal of pharmaceutical sciencesauthors
Sahoo G,Mulla NS,Ansari ZA,Mohandass Cdoi
10.4103/0250-474X.107068subject
Has Abstractpub_date
2012-07-01 00:00:00pages
348-51issue
4eissn
0250-474Xissn
1998-3743pii
IJPhS-74-348journal_volume
74pub_type
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