Abstract:
:The effect of food on the absorption characteristics of procainamide was assessed after oral administration of the drug to eight male patients in the fasting and postprandial states. Serum concentration-time curves showed no significant difference in peak serum levels of procainamide, in the time the peak value was reached, or in the area under the serum concentration-time curves, indicating the total amount of procainamide present in the serum. The bioavailability of procainamide appears not to be significantly altered by taking an oral dose with food.
journal_name
South Med Jjournal_title
Southern medical journalauthors
McKnight WD,Murphy MLdoi
10.1097/00007611-197607000-00013subject
Has Abstractpub_date
1976-07-01 00:00:00pages
851-2issue
7eissn
0038-4348issn
1541-8243journal_volume
69pub_type
杂志文章abstract::We reviewed 91 cases of neonatal necrotizing enterocolitis (NNEC), which continues to be a devastating disease occurring in 2% to 4% of all newborn intensive care unit admissions. Onset now occurs in older infants (11.9 days). The morbidity is significant (22%), with strictures (8%) and recurrences (8%) the primary pr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198411000-00010
更新日期:1984-11-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to determine the relation among multiple morbidities and the prevalence of colorectal cancer (CRC) screening among older adult Appalachian residents of Kentucky. This is the first known study to address multiple morbidities exclusively with a health-disparities population. METH...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31823a8879
更新日期:2011-12-01 00:00:00
abstract::We have presented the case of a 32-year-old man who sustained blunt trauma to the chest in a motor vehicle accident. Plain roentgenograms showed a widened mediastinum and pneumomediastinum, and an esophagogram with water-soluble contrast material showed an esophageal laceration at the T-4 level. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
abstract::The hypothenar hammer syndrome is a distinct entity of digital ischemia caused by the repetitive compression of the distal ulnar artery against the hook of the hamate. Definite diagnosis should most likely rely on selective arteriography. Primary resection with anastomosis and cervicodorsal sympathectomy have both bee...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198104000-00031
更新日期:1981-04-01 00:00:00
abstract::In a 61-year-old man with facial diplegia and new onset of congestive heart failure (CHF), electroneuromyography indicated diffuse axonal degeneration, but sural nerve biopsy showed mild changes and no amyloid. Four months later, after the onset of diplopia and increasing CHF, rectal biopsy demonstrated amyloid. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198611000-00037
更新日期:1986-11-01 00:00:00
abstract::The original and most widely accepted applications for point-of-care ultrasound (POCUS) are in the settings of trauma, shock, and bedside procedures. Trauma was the original setting for the introduction of POCUS and has been standardized under the four-plus view examination called the Focused Assessment with Sonograph...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000838
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Mortality rates for hyperthermia and hypothermia are higher in Alabama than nationally, and Alabama has twice as many hypothermia deaths as hyperthermia deaths. These causes of death have not been studied in the southeastern United States. We describe the epidemiology of heat- and cold-related deaths in Alab...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::Amiodarone, a benzofuran derivative, has proven useful in the control of serious cardiac arrhythmias. We reviewed the English language medical literature to characterize clinical, radiographic, scintigraphic, pathologic, diagnostic, and prognostic data concerning amiodarone pulmonary toxicity. Our review showed that f...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00
abstract::In 98 patients, we cannulated the subclavian and internal jugular veins with modified Shaldon catheters, using the Seldinger technic. Catheters were left for long periods, and multiple dialyses were accomplished with each catheter. The incidence of major complications was less than 5%. None of the catheters were belie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198209000-00016
更新日期:1982-09-01 00:00:00
abstract::The demented patient requires medical and often psychiatric supervision, but the caregiver is often neglected. This article identifies special issues for caregivers that may need attention from the demented patient's physician. The physician's attention can benefit both the patient and the caregiver and save the physi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::Many psychiatric patients experience pharmaceutical intolerances, and some of them do not derive optimal efficacy from their pharmacotherapies. Clinical problems such as these may result in prolonged dysfunction, adverse consequences, and repeated changes in medication treatment regimens. Pharmacogenomics is a laborat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000534
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:Program directors have noted that first-year residents struggle with many of the patient care responsibilities they assume as they enter the US graduate medical education system. A national description of medical students' patient care experience in advance of graduation has not been published. We sought to ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000738
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:Few tests of functional motor behavior are useful for rapidly screening people for lower extremity peripheral neuropathy. The goal of this study was to improve the widely used tandem walking (TW) test. METHODS:We tested "normal" (control) adult and ambulatory patients with peripheral neuropathy (PN) with the...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/SMJ.0000000000000009
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:In this study, we determined patients' attitudes toward discussing firearms and issues of firearms safety with emergency department physicians. We assessed whether patients feel discriminated against should physicians discuss firearms safety, and whether they believed that physician counseling may change how...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000915
更新日期:2019-01-01 00:00:00
abstract::Conventional rate limits for sinus rhythm--100/min as the tachycardia threshold and 60/min as the bradycardia threshold--were established by consensus and never formally examined. Because clinical experience indicated that both figures were too high, we investigated this formally in 500 normal individuals. Results wer...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199607000-00003
更新日期:1996-07-01 00:00:00
abstract::We studied 67 patients who had operation for perforated peptic ulcer. Operative treatment included plication with omentum (Graham closure) in 27 patients, vagotomy and pyloroplasty in 32 patients, or vagotomy and antrectomy in eight patients, depending on antecedent ulcer history, degree of contamination, and general ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198310000-00006
更新日期:1983-10-01 00:00:00
abstract::Pain is a tax levied on man for the privilege of life upon this planet. Some are taxed lightly and others are taxed heavily, but all are taxed. To relieve this stress, from time immemorial man has taken analgesics. In modern times, if home medication fails, professional consultation is available. The important questio...
journal_title:Southern medical journal
pub_type: 历史文章,杂志文章
doi:
更新日期:1980-12-01 00:00:00
abstract::The ultimate evolution of our case and its atypical features of unilateral blindness, bilateral involvement, and extensive involvement of the trigeminal nerve revealed the pathogenesis of this case of alternating painful ophthalmoplegia resembling the Tolosa-Hunt syndrome to be that of a parasellar pituitary adenoma. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198010000-00033
更新日期:1980-10-01 00:00:00
abstract::Most of the surgical procedures proposed for the treatment of fecal incontinence associated with prolapse are associated with considerable morbidity and mortality. We used a modified Thiersch procedure with a Silastic mesh implant (Dow-Corning 501-3) on a series of 12 patients over a period of 2 1/2 years. Nine patien...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198603000-00012
更新日期:1986-03-01 00:00:00
abstract::Millions of concussions occur every year in the United States. The public interest in concussion has increased after a number of high-profile deaths in high school athletes from sports-related head trauma and in some professional athletes from chronic traumatic encephalopathy. One of the most active areas of research ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0000000000000064
更新日期:2014-02-01 00:00:00
abstract::Brown recluse spider bites are usually self-limited skin lesions that infrequently progress to bullae, ulceration, and scarring. We treated a patient with a documented brown recluse bite who had recurring lesions resembling pyoderma gangrenosum (PG) that persisted for months. Three other patients referred to Vanderbil...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198503000-00012
更新日期:1985-03-01 00:00:00
abstract::The use of tourniquets for upper and lower extremity operative procedures is controversial in patients with sickle cell hemoglobinopathies. The authors used Ovid and MEDLINE®, PubMed, and CINAHL® to detect English-language reports of any surgical procedure where a tourniquet was used on a patient with sickle cell dise...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e3181efaf3b
更新日期:2010-11-01 00:00:00
abstract::Multiple sclerosis (MS) is among the most crippling diseases of the nervous system in young adults, and diagnosis can be difficult. It is true that MS can exist without magnetic resonance imaging or cerebrospinal fluid abnormalities, but whenever there are an atypical clinical pattern and no confirmatory laboratory te...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199603000-00008
更新日期:1996-03-01 00:00:00
abstract::A 37-year-old black man with presumed Pneumocystis carinii pneumonia who was treated with systemic IV pentamidine had fatal pancreatitis and massive hepatomegaly. Fatal pancreatitis can occur with no hemorrhagic changes seen at autopsy. Awareness of the relationship between pentamidine and pancreatitis should be empha...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
abstract::This case study supports the plea by a number of psychiatrists for thorough psychiatric and psychologic screening of all persons seeking sexual reassignment surgery. The patient, a female impersonator taking estrogen, was seriously considering such an operation in order to cope with identity problems and an inability ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197504000-00017
更新日期:1975-04-01 00:00:00
abstract::Two patients with obstruction of the pulmonary veins by bronchogenic carcinoma, an unusual cause, are presented. These and other cases reported have had features suggestive of mitral stenosis. The differential diagnosis is discussed. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197611000-00027
更新日期:1976-11-01 00:00:00
abstract::A woman with stable diabetes presented with hypoglycemia and decreased insulin requirement. Further history suggested decreasing pituitary function. Laboratory tests confirmed pituitary deficiencies, associated with her increased insulin sensitivity. It may be helpful to be aware of this syndrome when dealing with dia...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198001000-00033
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:This study was performed to examine the effect of stress on pregnancy outcome in women who underwent assisted reproductive technology (ART) procedures. METHODS:In a controlled clinical study of healthy volunteers in an academic research environment, stress was measured subjectively by administering patient ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000054567.79881.E9
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To determine whether racial disparities occurred among specialty and allied health inpatient consultations for patients admitted to adult hospital services at an academic hospital. METHODS:A retrospective data analysis of the first 2000 patients, ages 18 years or older, admitted to an academic hospital. RES...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000001084
更新日期:2020-04-01 00:00:00
abstract::Dietary advice based on saturated versus unsaturated fatty acids for the purpose of controlling the plasma cholesterol level has for many years plagued the American public with unpalatable diets that are difficult to adhere to. Stearic acid, an 18-carbon saturated fatty acid, does not share the hypercholesterolemic ef...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199201000-00007
更新日期:1992-01-01 00:00:00