The effect of food on procainamide absorption.

Abstract:

:The effect of food on the absorption characteristics of procainamide was assessed after oral administration of the drug to eight male patients in the fasting and postprandial states. Serum concentration-time curves showed no significant difference in peak serum levels of procainamide, in the time the peak value was reached, or in the area under the serum concentration-time curves, indicating the total amount of procainamide present in the serum. The bioavailability of procainamide appears not to be significantly altered by taking an oral dose with food.

journal_name

South Med J

journal_title

Southern medical journal

authors

McKnight WD,Murphy ML

doi

10.1097/00007611-197607000-00013

subject

Has Abstract

pub_date

1976-07-01 00:00:00

pages

851-2

issue

7

eissn

0038-4348

issn

1541-8243

journal_volume

69

pub_type

杂志文章
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