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Phthalates: European regulation, chemistry, pharmacokinetic and related toxicity.

Abstract：

:Phthalates are chemicals widely used in industry and the consequences for human health caused by exposure to these agents are of significant current interest. Phthalate toxicity targets the reproductive and respiratory systems primarily, but they also may be involved in the processes of carcinogenesis and even in autism spectrum disorders. This article discusses the molecular and cellular mechanisms involved in organ toxicity of phthalates; furthermore, pharmacokinetic, chemistry and the European regulation are summarized.

journal_name

Environ Toxicol Pharmacol

journal_title

Environmental toxicology and pharmacology

authors

Ventrice P,Ventrice D,Russo E,De Sarro G

doi

10.1016/j.etap.2013.03.014

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

88-96

issue

1

eissn

1382-6689

issn

1872-7077

pii

S1382-6689(13)00073-2

journal_volume

36

pub_type

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