Abstract:
:Three experiments investigated the role of the dorsal hippocampus (DH) in renewal of conditioned and then extinguished magazine approach responding in rats. Experiments 1 and 2 found no effect of muscimol inactivation of the DH during testing on ABA and ABC renewal, respectively. However, subjects from these studies were subsequently found to be impaired on a delayed non-matching-to-place task following muscimol but not saline infusions. Experiment 3 found no effects of post-training excitotoxic lesions of the DH on ABA and ABC renewal. Lesioned subjects were, however, impaired on the delayed non-matching-to-place task compared to control subjects. These findings suggest that the DH may not play a similar role in Pavlovian extinction in appetitive learning tasks as has previously been reported in aversive learning.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Campese V,Delamater ARdoi
10.1016/j.bbr.2013.03.044subject
Has Abstractpub_date
2013-07-01 00:00:00pages
62-73eissn
0166-4328issn
1872-7549pii
S0166-4328(13)00186-1journal_volume
248pub_type
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