Tissue engineering and regenerative medicine as applied to the gastrointestinal tract.

Abstract:

:The gastrointestinal (GI) tract is a complex system characterized by multiple cell types with a determined architectural arrangement. Tissue engineering of the GI tract aims to reinstate the architecture and function of all structural layers. The key point for successful tissue regeneration includes the use of cells/biomaterials that elucidate minimal immune response after implantation. Different biomaterial choices and cell sources have been proposed to engineer the GI tract. This review summarizes the recent advances in bioengineering the GI tract with emphasis on cell sources and scaffolding biomaterials.

journal_name

Curr Opin Biotechnol

authors

Bitar KN,Zakhem E

doi

10.1016/j.copbio.2013.03.021

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

909-15

issue

5

eissn

0958-1669

issn

1879-0429

pii

S0958-1669(13)00078-5

journal_volume

24

pub_type

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