Elastostatics of a spherical inclusion in homogeneous biological media.

abstract：:Radiation therapy is an image-guided process whose success critically depends on the imaging modality used for treatment planning and the level of integration of the available imaging information. In this work, we establish a dose optimization framework for incorporating metabolic information from functional imaging m...

journal_title：Physics in medicine and biology

authors： Xing L,Cotrutz C,Hunjan S,Boyer AL,Adalsteinsson E,Spielman D

更新日期：2002-10-21 00:00:00

abstract：:In radiotherapy with photon beams, the use of dynamic wedges, which are obtained by the movement of one of the jaws, offers an increasing flexibility relative to the traditional use of metal wedges. But it is a disadvantage for the measurement of absorbed dose distributions, because the absorbed dose at each measureme...

journal_title：Physics in medicine and biology

authors： Storchi P,Woudstra E,Verlinde P,Johansson KA,Samuelsson A

更新日期：1998-06-01 00:00:00

abstract：:We developed an anatomy-guided 4D closed-form algorithm to directly reconstruct parametric images from projection data for (nearly) irreversible tracers. Conventional methods consist of individually reconstructing 2D/3D PET data, followed by graphical analysis on the sequence of reconstructed image frames. The propose...

journal_title：Physics in medicine and biology

authors： Tang J,Kuwabara H,Wong DF,Rahmim A

更新日期：2010-08-07 00:00:00

abstract：:109Cd K x-ray fluorescence (XRF) measurement systems from two research centres were used to measure tibia lead content in a population (n = 530) of young adults. The group mean bone lead contents (+/-SEM) determined by McMaster University (n = 214) and the University of Maryland (n = 316) were 2.80 +/- 0.51 and 2.33 +...

journal_title：Physics in medicine and biology

authors： McNeill FE,Stokes L,Chettle DR,Kaye WE

更新日期：1999-09-01 00:00:00

abstract：:Burst-tone focused ultrasound exposure in the presence of microbubbles has been demonstrated to be effective at inducing temporal and local opening of the blood-brain barrier (BBB), which promises significant clinical potential to deliver therapeutic molecules into the central nervous system (CNS). Traditional contras...

journal_title：Physics in medicine and biology

authors： Tsai CH,Zhang JW,Liao YY,Liu HL

更新日期：2016-04-07 00:00:00

abstract：:Spinal screw placement is a challenging task due to small bone corridors and high risk of neurological or vascular complications, benefiting from precision guidance/navigation and quality assurance (QA). Implicit to both guidance and QA is the definition of a surgical plan-i.e. the desired trajectories and device sele...

journal_title：Physics in medicine and biology

authors： Goerres J,Uneri A,De Silva T,Ketcha M,Reaungamornrat S,Jacobson M,Vogt S,Kleinszig G,Osgood G,Wolinsky JP,Siewerdsen JH

更新日期：2017-04-07 00:00:00

abstract：:Kilo-voltage (KV) cone-beam computed tomography (CBCT) unit mounted onto a linear accelerator treatment system, often referred to as on-board imager (OBI), plays an increasingly important role in image-guided radiation therapy. While the FDK algorithm is currently used for reconstructing images from clinical OBI data,...

journal_title：Physics in medicine and biology

authors： Han X,Pearson E,Pelizzari C,Al-Hallaq H,Sidky EY,Bian J,Pan X

更新日期：2015-06-21 00:00:00

abstract：:The purpose of this study was the characterization of local magnetic susceptibility deviations by spectral analysis of their induced magnetic field inhomogeneities. Magnetic resonance spectra and related signal decay curves of local susceptibility deviations were simulated for different volume fractions and compositio...

journal_title：Physics in medicine and biology

authors： Seppenwoolde JH,van Zijtveld M,Bakker CJ

更新日期：2005-01-21 00:00:00

abstract：:An ESTRO booklet and a report of the Netherlands Commission on Radiation Dosimetry have been published recently describing empirical methods for monitor unit (MU) calculations in symmetrical high-energy photon beams. Both documents support the same basic ideas; firstly the separation of head scatter and volume scatter...

journal_title：Physics in medicine and biology

authors： Georg D

更新日期：1999-12-01 00:00:00

abstract：:Amorphous silicon (aSi:H) flat panel detectors are prevalent in radiotherapy for megavoltage imaging tasks. Any clinical and dosimetrical application requires a well-defined dose response of the system to achieve meaningful results. Due to radiation damages, panels deteriorate and the linearity of pixel response to do...

journal_title：Physics in medicine and biology

authors： Huber S,Mooslechner M,Mitterlechner B,Weichenberger H,Serpa M,Sedlmayer F,Deutschmann H

更新日期：2013-09-21 00:00:00

abstract：:In magnetic drug targeting a chemotherapeutic agent is bound to coated magnetic nanoparticles, which are administered to the blood vessel system and subsequently focused by an external applied magnetic field. The optimization of intra-arterial magnetic drug targeting (MDT) requires detailed knowledge about the biodist...

journal_title：Physics in medicine and biology

authors： Richter H,Wiekhorst F,Schwarz K,Lyer S,Tietze R,Alexiou Ch,Trahms L

更新日期：2009-09-21 00:00:00

abstract：:A novel digital x-ray detector has been assembled. The imaging system is based on a phosphor-coated charge-coupled device (CCD) obtained by direct deposition of a gadolinium oxysulphide scintillator onto the detector surface. The modulation transfer function has been measured along the two directions of the digital co...

journal_title：Physics in medicine and biology

authors： Gambaccini M,Taibi A,Del Guerra A,Marziani M,Tuffanelli A

更新日期：1996-12-01 00:00:00

abstract：:We report the first experimental soft-tissue phase-contrast tomography results using a conventional x-ray tube source, with a millimeter-sized focal spot. The setup is based on a Talbot-Lau grating interferometer operated at a mean energy of 28 keV. We present three-dimensional ex vivo images of a chicken heart sample...

journal_title：Physics in medicine and biology

authors： Bech M,Jensen TH,Feidenhans'l R,Bunk O,David C,Pfeiffer F

更新日期：2009-05-07 00:00:00

abstract：:The interest in positron emission tomography (PET) and particularly in hybrid integrated PET/CT systems has significantly increased in the last few years due to the improved quality of the obtained images. Nevertheless, one of the most important limits of the PET imaging technique is still its poor spatial resolution ...

journal_title：Physics in medicine and biology

authors： Rapisarda E,Bettinardi V,Thielemans K,Gilardi MC

更新日期：2010-07-21 00:00:00

abstract：:In addition to being a powerful clinical tool, Positron emission tomography (PET) is also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. However, dosi...

journal_title：Physics in medicine and biology

authors： Xie T,Zaidi H

更新日期：2013-01-07 00:00:00

abstract：:A modified sector-integration method is presented that can predict the output factors of irregular shaped electron fields even in the case of extended source to surface distance (SSD). The model takes as input measured output factors for circular inserts of various radii. These circular fields were measured at SSDs of...

journal_title：Physics in medicine and biology

authors： Choi DR,Wolters J,Mason D,Baillie A

更新日期：2000-11-01 00:00:00

abstract：:Scattered doses, e.g. neutron doses in proton therapy, are of concern in radiation therapy. Although measured data are the gold standard, Monte Carlo simulations allow a more realistic consideration of patient anatomy via whole-body phantoms. When calculating neutron doses with Monte Carlo techniques, the dose can be ...

journal_title：Physics in medicine and biology

authors： Jarlskog CZ,Paganetti H

更新日期：2008-09-07 00:00:00

abstract：:An accurate, low noise estimate of photon attenuation in the subject is required for quantitative microPET studies of molecular tracer distributions in vivo. In this work, several transmission-based measurement techniques were compared, including coincidence mode with and without rod windowing, singles mode with two d...

journal_title：Physics in medicine and biology

authors： Lehnert W,Meikle SR,Siegel S,Newport D,Banati RB,Rosenfeld AB

更新日期：2006-08-21 00:00:00

abstract：:Elastography, which uses ultrasound to image the tissue strain that results from an applied displacement, can display tumours and heat-ablated tissue with high contrast. However, its application to liver in vivo may be problematic due to the presence of respiratory and cardiovascular sources of displacement. The aim o...

journal_title：Physics in medicine and biology

authors： Kolen AF,Miller NR,Ahmed EE,Bamber JC

更新日期：2004-09-21 00:00:00

abstract：:In digital breast tomosynthesis (DBT), image characteristics of projection views and reconstructed volume are different and both have the advantage of detecting breast masses, e.g. reconstructed volume mitigates a tissue overlap, while projection views have less reconstruction blur artifacts. In this paper, an improve...

journal_title：Physics in medicine and biology

authors： Kim DH,Kim ST,Ro YM

更新日期：2015-11-21 00:00:00

abstract：:The combined build-up and attenuation factor, B exp (-mu r), of point isotropic photon sources in a water medium has been calculated using the Monte Carlo method, for energies (20-1500 keV) and distances (1-10 cm) relevant in brachytherapy. For the transport of photons and electrons, up-to-date and self-consistent tot...

journal_title：Physics in medicine and biology

authors： Angelopoulos A,Perris A,Sakellariou K,Sakelliou L,Sarigiannis K,Zarris G

更新日期：1991-06-01 00:00:00

abstract：:Nanocarriers offer a promising approach to significantly improve therapeutic delivery to solid tumors as well as limit the side effects associated with anti-cancer agents. However, their relatively large size can negatively affect their ability to efficiently penetrate into more interior tumor regions, ultimately redu...

journal_title：Physics in medicine and biology

authors： Mohammadabadi A,Huynh RN,Wadajkar AS,Lapidus RG,Kim AJ,Raub CB,Frenkel V

更新日期：2020-06-22 00:00:00

abstract：:Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted from pre-treatment diffusion-weighted magnetic resonance images (DWIs) for predi...

journal_title：Physics in medicine and biology

authors： Fu J,Zhong X,Li N,Van Dams R,Lewis J,Sung K,Raldow AC,Jin J,Qi XS

更新日期：2020-04-02 00:00:00

abstract：:A formalism is proposed for the estimation of mean glandular dose for breast tomosynthesis, which is a simple extension of the UK, European and IAEA protocols for dosimetry in conventional projection mammography. The formalism introduces t-factors for the calculation of breast dose from a single projection and T-facto...

journal_title：Physics in medicine and biology

authors： Dance DR,Young KC,van Engen RE

更新日期：2011-01-21 00:00:00

abstract：:Monte Carlo simulations are used to investigate skin dose resulting from chest wall radiotherapy with bolus. A simple model of a female thorax is developed, which includes a 2 mm-thick skin layer. Two representative 6 MV source models are considered: a tangents source model consisting of a parallel opposed pair of med...

journal_title：Physics in medicine and biology

authors： Oliver PAK,Monajemi TT

更新日期：2020-08-11 00:00:00

abstract：:As a prerequisite for clinical treatments it was necessary to characterize the Elekta 1.5 T MRI-linac 7 MV FFF radiation beam. Following acceptance testing, beam characterization data were acquired with Semiflex 3D (PTW 31021), microDiamond (PTW 60019), and Farmer-type (PTW 30013 and IBA FC65-G) detectors in an Elekta...

journal_title：Physics in medicine and biology

authors： Woodings SJ,Bluemink JJ,de Vries JHW,Niatsetski Y,van Veelen B,Schillings J,Kok JGM,Wolthaus JWH,Hackett SL,van Asselen B,van Zijp HM,Pencea S,Roberts DA,Lagendijk JJW,Raaymakers BW

更新日期：2018-04-19 00:00:00

abstract：:Recent studies have demonstrated the feasibility of transcranial high-intensity focused ultrasound (HIFU) therapy in the brain using adaptive focusing techniques. However, the complexity of the procedures imposes provision of accurate targeting, monitoring and control of this emerging therapeutic modality in order to ...

journal_title：Physics in medicine and biology

authors： Larrat B,Pernot M,Aubry JF,Dervishi E,Sinkus R,Seilhean D,Marie Y,Boch AL,Fink M,Tanter M

更新日期：2010-01-21 00:00:00

abstract：:Although field area and object thickness are important parameters in comparisons of techniques for optimal reduction of scattered radiation to the image, they are in practice seldom varied. For this reason, we suggest that contrast degradation (CDF) and contrast improvement (CIF) factors be more frequently used and ap...

journal_title：Physics in medicine and biology

authors： Carlsson GA,Carlsson CA,Nielsen B,Persliden J

更新日期：1986-07-01 00:00:00

abstract：:Cardiac and respiratory motion artefacts in PET imaging have been traditionally resolved by acquiring the data in gated mode. However, gated PET images are usually characterized by high noise content due to their low photon statistics. In this paper, we present a novel 4D model for the PET imaging system, which can in...

journal_title：Physics in medicine and biology

authors： Qiao F,Pan T,Clark JW Jr,Mawlawi OR

更新日期：2006-08-07 00:00:00

abstract：:Three-dimensional reconstruction of coronary arteries can be performed during x-ray-guided interventions by gated reconstruction from a rotational coronary angiography sequence. Due to imperfect gating and cardiac or breathing motion, the heart's motion state might not be the same in all projections used for the recon...

journal_title：Physics in medicine and biology

authors： Hansis E,Schäfer D,Dössel O,Grass M

更新日期：2008-07-21 00:00:00