Activation of c-Jun NH2-terminal kinases by interleukin-1 beta in normal human osteoblastic and rat UMR-106 cells.

abstract：:Extracts of thymic lymphoma that are obtained from AKR mice and are kept in the cold for at least several days can induce lipolytic activity in rat adipocyte suspensions. Freshly prepared extracts have low activity but contain a low molecular weight material of less than 10,000 daltons that aggregates on standing in t...

journal_title：Journal of cellular biochemistry

authors： Kitada S,Hays EF,Mead JF,Zabin I

更新日期：1982-01-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants whose effects on biological systems depend on the number of and the positions of the chlorine substitutions. In the present study we examined the estrogenicity of the fully ortho-substituted PCB, 2,2',6,6'-tetrachlorobiphenyl (2,2',6,6'-TeCB). ...

journal_title：Journal of cellular biochemistry

authors： Arcaro KF,Yi L,Seegal RF,Vakharia DD,Yang Y,Spink DC,Brosch K,Gierthy JF

更新日期：1999-01-01 00:00:00

abstract：:Mutants of type 5 adenovirus that lack all or part of the early region 1A (E1A) gene enhancer element transform rodent embryo fibroblast (CREF) cells at higher efficiencies than wild-type virus. An analysis of viral E1A cytoplasmic mRNA levels in mutant and wild-type virus-infected CREF cells revealed no differences i...

journal_title：Journal of cellular biochemistry

authors： Herbst RS,Pelletier M,Babiss LE

更新日期：1990-01-01 00:00:00

abstract：:Thrombin is a potent mitogen for human vascular smooth muscle cells (HVSMC) and its enzymatic activity is required for this function. The present study demonstrates that prothrombin is also mitogenic for HVSMC due to the generation of enzymatically active thrombin which occurs upon incubation of prothrombin with the c...

journal_title：Journal of cellular biochemistry

authors： Benzakour O,Kanthou C,Lupu F,Dennehy U,Goodwin C,Scully MF,Kakkar VV,Cooper DN

更新日期：1995-12-01 00:00:00

abstract：:Relatively little information exists on the ultimate molecular mechanisms by which the lipogenic enzyme Fatty Acid Synthase (FAS) is differentially overexpressed in a biologically aggressive subset of human malignancies. Since the microenvironment of solid tumors contains regions of poor oxygenation and high acidity, ...

journal_title：Journal of cellular biochemistry

authors： Menendez JA,Decker JP,Lupu R

更新日期：2005-01-01 00:00:00

abstract：:Acute kidney injury (AKI) is a common kidney disorder that affects public health and the incidence of AKI. Sepsis, acute ischemia or hypoxia is the main reason for the occurrence of AKI. Recently, noncoding RNA that include microRNA and long noncoding RNA (lncRNAs) were reported to play important roles in AKI as well ...

journal_title：Journal of cellular biochemistry

authors： Jiang X,Li D,Shen W,Shen X,Liu Y

更新日期：2019-09-01 00:00:00

abstract：:Prion diseases are characterized by the presence of an abnormal isoform of the cellular prion protein (PrPc) whose physiological role still remains elusive. To better understand the function of PrPc, it is important to identify the different subcellular localization(s) of the protein and the different partners with wh...

journal_title：Journal of cellular biochemistry

authors： Rybner C,Finel-Szermanski S,Felin M,Sahraoui T,Rousseau C,Fournier JG,Sève AP,Botti J

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Gram-negative bacterium, Helicobacter pylori is notorious for various pathologies like peptic ulcers, gastritis, functional dyspepsia, and various cancers. METHODS:Systemic effects of its toxins have led scientists' attention toward the extragastric pathologies associated with it. To date, it has been shown...

journal_title：Journal of cellular biochemistry

authors： Zendehdel A,Roham M

更新日期：2019-08-01 00:00:00

abstract：:Cranial sutures are important growth sites of the skull. During suture closure, the dura mater is one of the most important sources of various positive and negative regulatory signals. Previous results indicate that TGF-beta2 from dura mater strongly accelerates suture closure, however, its exact regulatory mechanism ...

journal_title：Journal of cellular biochemistry

authors： Lee SW,Choi KY,Cho JY,Jung SH,Song KB,Park EK,Choi JY,Shin HI,Kim SY,Woo KM,Baek JH,Nam SH,Kim YJ,Kim HJ,Ryoo HM

更新日期：2006-07-01 00:00:00

abstract：:Muscle progenitor cells differentiate to myoblasts, and subsequently myotubes, upon expression of muscle specific genes. We and others have previously shown that myotube nuclei, even in the absence of nerve, express AChR alpha subunit RNA at varying levels, with a small subset (about ten percent) of the nuclei express...

journal_title：Journal of cellular biochemistry

authors： Su X,Berman SA,Sullivan T,Bursztajn S

更新日期：1995-05-01 00:00:00

abstract：:Carotenoid cleavage dioxygenase (CCD) gene, ubiquitously found in numerous types of plants, are eminent in synthesizing the various volatile compounds (β-ionone, C13 -norisoprenoid, geranylacetone) known as apocarotenoids. These apocarotenoids have various biological functions such as volatile signals, allelopathic in...

journal_title：Journal of cellular biochemistry

authors： Priya R,Sneha P,Rivera Madrid R,Doss CGP,Singh P,Siva R

更新日期：2017-09-01 00:00:00

abstract：:Generation of osteoblasts from human somatic cells may be applicable in an effective transplantation therapy against bone diseases. Recently we established a procedure to directly convert human fibroblasts into osteoblasts by transducing some transcription factor genes via retroviral vectors. However, retroviral vecto...

journal_title：Journal of cellular biochemistry

authors： Yamamoto K,Sato Y,Honjo K,Ichioka H,Oseko F,Sowa Y,Yamamoto T,Kanamura N,Kishida T,Mazda O

更新日期：2016-11-01 00:00:00

abstract：:The cholesterol hydroxylase/lyase (CHL) system, consisting of cytochrome P450scc, adrenodoxin (Adx) and adrenodoxin reductase (AdR), initiates mammalian steroidogenesis, converting cholesterol to pregnenolone. The foot-and-mouth disease virus 2A-based method allows to express multiple proteins from a single transcript...

journal_title：Journal of cellular biochemistry

authors： Efimova VS,Isaeva LV,Labudina AA,Tashlitsky VN,Rubtsov MA,Novikova LA

更新日期：2019-03-01 00:00:00

abstract：:The receptor for epidermal growth factor (EGF) is a glycosylated transmembrane phosphoprotein that exhibits EGF-stimulable protein tyrosine kinase activity. On EGF stimulation, the receptor undergoes a self-phosphorylation reaction at tyrosine residues located primarily in the extreme carboxyl-terminal region of the p...

journal_title：Journal of cellular biochemistry

authors： Bertics PJ,Weber W,Cochet C,Gill GN

更新日期：1985-01-01 00:00:00

abstract：:Tissue factor, the cellular initiator of blood coagulation, has been implicated as a determinant of metastatic potential in human melanoma cells. Here, we report that differential expression of tissue factor in murine melanoma cell lines of known metastatic behavior is mediated by AP-1-dependent and 12S E1A oncoprotei...

journal_title：Journal of cellular biochemistry

authors： Voigtländer C,Rand A,Liu SL,Wilson TJ,Pittelkow MR,Getz MJ,Kelm RJ Jr

更新日期：2002-01-01 00:00:00

abstract：:D-Galactose (D-gal) can induce oxidative stress in non-cancer cells and result in cell damage by disturbing glucose metabolism. However, the effect of D-gal on cancer cells is yet to be explored. In this study, we investigated the toxicity of D-gal to malignant cells specifically neuroblastoma cells. As the results, h...

journal_title：Journal of cellular biochemistry

authors： Li N,He Y,Wang L,Mo C,Zhang J,Zhang W,Li J,Liao Z,Tang X,Xiao H

更新日期：2011-12-01 00:00:00

abstract：:Cervical cancer is one of the leading killers for female worldwide. Nevertheless, the less knowledge of molecular mechanism for cervical cancer limited the improvement of treatment effects. High-mobility group box 2 (HMGB2) belongs to the HMGB family, which could play diverse roles in cell proliferation. This work mai...

journal_title：Journal of cellular biochemistry

authors： Zhang P,Lu Y,Gao S

更新日期：2019-10-01 00:00:00

abstract：:Osteosarcoma (OS) is the most malignant primary bone tumor in children and adolescents with limited treatment options and poor prognosis. Recently, aberrant expression of Runx2 has been found in OS, thereby contributing to the development, and progression of OS. However, the upstream signaling molecules that regulate ...

journal_title：Journal of cellular biochemistry

authors： Liang GH,Liu N,He MT,Yang J,Liang ZJ,Gao XJ,Rahhal AH,He QY,Zhang HT,Zha ZG

更新日期：2018-01-01 00:00:00

abstract：:Acetylation of histones leads to conformational changes of DNA. We have previously shown that the histone deacetylase (HDAC) inhibitor, suberoylanilide hydroxamic acid (SAHA), induced cell cycle arrest, differentiation, and apoptosis. In addition to their antitumor effects as single agents, HDAC inhibitors may cause c...

journal_title：Journal of cellular biochemistry

authors： Marchion DC,Bicaku E,Daud AI,Richon V,Sullivan DM,Munster PN

更新日期：2004-05-15 00:00:00

abstract：:Nonalcoholic steatohepatitis (NASH) is currently the third most common cause of end stage liver disease necessitating transplantation. The question remains how inflammation and NASH develop in the setting of nonalcoholic fatty liver disease (NAFLD) and steatosis. Understand the roles of toll-like receptor 4 (TLR4) and...

journal_title：Journal of cellular biochemistry

authors： Sutter AG,Palanisamy AP,Lench JH,Esckilsen S,Geng T,Lewin DN,Cowart LA,Chavin KD

更新日期：2016-07-01 00:00:00

abstract：:The role of excision repair cross-complimentary group 1 (ERCC1) gene polymorphisms in breast and ovarian cancer development has long been controversial and existing data were inconsistent. Here, we conducted a comprehensive meta-analysis to better clarify the association. Case-control studies published from December 2...

journal_title：Journal of cellular biochemistry

authors： Yang F,Mu X,Bian C,Zhang H,Yi T,Zhao X,Lin X

更新日期：2019-09-01 00:00:00

abstract：:Osteosarcoma cells are recognized by abnormal function that causes a primary bone tumor. Osteosarcoma cells U(2)OS and SAOS-2 were analyzed for the expression of cell surface markers. High expression was quantified for hyaloronidase receptor (CD-44) > moderate for integrins (CD-51 and -61), > and lower for selectins (...

journal_title：Journal of cellular biochemistry

authors： Benayahu D,Shur I,Marom R,Meller I,Issakov J

更新日期：2001-01-01 00:00:00

abstract：:Calcium-dependent cell adhesion molecules (CAMs) mediate intercellular adhesion in epithelial cells and in preimplantation mammalian embryos. One of these molecules, cell-CAM 120/80, is found on cells as a 120-kd membrane glycoprotein and as a soluble 80-kd species in conditioned culture medium [Damsky et al: Cell 34:...

journal_title：Journal of cellular biochemistry

authors： Wheelock MJ,Buck CA,Bechtol KB,Damsky CH

更新日期：1987-07-01 00:00:00

abstract：:17β-Estradiol (E2 ) protects several nonreproductive tissues from apoptosis, including skeletal muscle. Previously, we showed that E2 at physiological concentrations prevented apoptosis induced by H2 O2 in skeletal myoblasts, reverting PKCδ, JNK, and p66Shc activation and exerting a beneficial action over mitochondria...

journal_title：Journal of cellular biochemistry

authors： La Colla A,Vasconsuelo A,Milanesi L,Pronsato L

更新日期：2017-01-01 00:00:00

abstract：:In previous studies we have shown that all-trans retinoic acid (atRA)-treatment of the atRA-sensitive ovarian carcinoma cell line CA-OV3 repressed AP-1 activity by about 50%, while a similar effect was not observed in the atRA-resistant ovarian carcinoma cell line, SK-OV3. These results suggested that the repression o...

journal_title：Journal of cellular biochemistry

authors： Ramírez CJ,Haberbusch JM,Soprano DR,Soprano KJ

更新日期：2005-09-01 00:00:00

abstract：:Adamts17 is a member of a family of secreted metalloproteinases. In this report, we show that knockdown of Adamts17 expression induces apoptosis and inhibits breast cancer cell growth. Adamts17 expression can rapidly be induced by estrogens. siRNA knockdown of Sp1 or Myc demonstrated that Sp1 is required to induce Ada...

journal_title：Journal of cellular biochemistry

authors： Jia Z,Gao S,M'Rabet N,De Geyter C,Zhang H

更新日期：2014-10-01 00:00:00

abstract：:Gold nanoparticles (AuNP's) facilitate cancer cell recognition and can be manufactured by green synthesis using nutrient rich medicinal plants such as Moringa oleifera (MO). Targeting dysregulated oncogenes and tumor suppressor genes is crucial for cancer therapeutics. We investigated the antiproliferative effects of ...

journal_title：Journal of cellular biochemistry

authors： Tiloke C,Phulukdaree A,Anand K,Gengan RM,Chuturgoon AA

更新日期：2016-10-01 00:00:00

abstract：:As an extension of our recently published work (Mlejnek and Kuglík [2000] J. Cell. Biochem. 77:6-17), the role of caspases in N(6)-benzylaminopurine riboside (BAPR)-induced apotosis in HL-60 cells was evaluated in this study. Here, BAPR-induced apoptosis was accompanied by activation of caspase-3 and caspase-9. Howeve...

journal_title：Journal of cellular biochemistry

authors： Mlejnek P

更新日期：2001-01-01 00:00:00

abstract：:Albuminuria is indicative of nephropathy. However, little literature has focused on the role of albumin in renal distal tubule fibrosis. We used a well-defined distal tubule cell, Madin-Darby Canine Kidney (MDCK). Proliferation and cytotoxicity were examined. The conditioned supernatant was collected and subjected to ...

journal_title：Journal of cellular biochemistry

authors： Liu HC,Liao TN,Lee TC,Chuang LY,Guh JY,Liu SF,Hu MS,Yang YL,Lin SH,Hung MY,Huang JS,Hung TJ,Chen CD,Chiang TA,Chan JY,Chen SY,Yang YL

更新日期：2006-04-01 00:00:00

abstract：:Mounting evidence showed that microRNAs involve in development and chemoresistance of various human cancers. We explored the roles and mechanisms of miR-144 in resistance to cisplatin (CDDP) of cervical cancer cells. miR-144 and LIM homeobox 2 (LHX2) expression in CDDP-resistant and the parental cells was determined b...

journal_title：Journal of cellular biochemistry

authors： Shi F,Su J,Liu Z,Wang J,Wang T

更新日期：2019-09-01 00:00:00