Influence of mycobacterial virulence and culture condition on gamma delta T cell activation.

Abstract:

:Activation of human gamma delta T cells by culture supernatants of virulent and avirulent mycobacteria was examined. The stimulatory potential of mycobacteria was influenced by the type of culture media and independent from their virulence. Activation of gamma delta T cells by phagocytes infected with viable virulent Mycobacterium tuberculosis H37Rv and avirulent M. bovis BCG was comparable. We conclude that gamma delta T cell stimulation occurs in response to infection with mycobacteria independent from their virulence.

journal_name

Microb Pathog

journal_title

Microbial pathogenesis

authors

Schoel B,Kaufmann SH

doi

10.1006/mpat.1997.0187

subject

Has Abstract

pub_date

1998-03-01 00:00:00

pages

197-201

issue

3

eissn

0882-4010

issn

1096-1208

pii

S0882-4010(97)90187-X

journal_volume

24

pub_type

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