Abstract:
:Pulmonary shunting (Qs/Qt) was measured in 16 anesthetized and paralyzed healthy beagle puppies during a control period when the end-expired CO2 concentration was 5 per cent and during alveolar hypoventilation, when the PaCO2 increased to 100 plus or minus 13 torr (mean plus or minus SE) and the ;Ha vecame 7.04 plus or minus 0.04. A constant tidal volume was maintained throughout each study, and hypoventilation was achieved by slowing only the respiratory rate. During the control period Qs/Qt was 2.9 plus or minus 0.3 per cent; during hypoventilation Qs/Qt was 3.2 plus or minus 0.3 per cent (an insignificant difference). The puppies, therefore, responded to anesthesia and alveolar hypoventilation without development of increased pulmonary shunts.
journal_name
Anesthesiologyjournal_title
Anesthesiologyauthors
Stone JG,Sullivan SFdoi
10.1097/00000542-197504000-00014subject
Has Abstractpub_date
1975-04-01 00:00:00pages
443-50issue
4eissn
0003-3022issn
1528-1175journal_volume
42pub_type
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