Abstract:
UNLABELLED:Yeasts occur as part of the normal human microbiota. Nevertheless, some species are opportunistic, affecting immunocompromised patients such as those undergoing oncologic treatment. OBJECTIVE:To detect the presence of yeasts in patients suffering from head and neck cancer who are receiving radiation therapy and display lesions in the oral cavity, compatible with candidiasis; and to evaluate the antifungal susceptibility of the isolates recovered. METHODS:Sixty samples from patients were obtained by swabbing the oral mucosa. Identification of isolates were performed by classical taxonomic, morphological and biochemical methods as well as by using commercial identification kits. Susceptibility to antifungal drugs was determined by the agar diffusion method with Neosensitabs(®) disks. RESULTS:Forty-six samples (77%) yielded positive findings, and species recovered were: Candida albicans (22 isolates), Candida tropicalis (13 isolates), Candida parapsilosis (six strains), Candida krusei (three strains), Candida dubliniensis and Saccharomyces cerevisiae (one each). All strains were susceptible to itraconazole, clotrimazole, voriconazole, nystatin and amphotericin B. On the other hand, 65% of strains were miconazole-susceptible while 35%, showed intermediate susceptibility. With regard to ketoconazole, only three strains (7%) corresponding to C. albicans (one isolate) and C. krusei (two isolates) displayed intermediate susceptibility. Only C. krusei strains were resistant to fluconazole while all the other species were susceptible. Eventually, only six isolates (13%) were susceptible to terbinafine while the remaining strains were resistant in vitro. CONCLUSION:Early detection of etiological agents causing lesions, as well as the evaluation of their susceptibility to commonly used drugs, are crucial in order to choose the appropriate treatment that will minimize complications while improving the quality of patients' lives.
journal_name
J Mycol Medjournal_title
Journal de mycologie medicaleauthors
Bulacio L,Paz M,Ramadán S,Ramos L,Pairoba C,Sortino M,Escovich L,López Cdoi
10.1016/j.mycmed.2012.08.002subject
Has Abstractpub_date
2012-12-01 00:00:00pages
348-53issue
4eissn
1156-5233issn
1773-0449pii
S1156-5233(12)00144-8journal_volume
22pub_type
杂志文章abstract:OBJECTIVE:To determine the fungal species isolated from skin lesions of different animals suspected of having dermatomycoses and their prevalence in different regions of Iran. MATERIALS AND METHODS:A total of 1011 animals (292 dogs, 229 cats, 168 horses, 100 camels, 98 cows, 60 squirrels, 37 birds, 15 sheep, 6 goats, ...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2016.04.007
更新日期:2016-06-01 00:00:00
abstract::Malassezia pachydermatis is an important opportunistic agent of dermatitis and otitis in dogs. M. pachydermatis is generally treated with topical therapies using combinations of antifungal, antimicrobial and anti-inflammatory agents. We investigated the in vitro activities of carvacrol (CRV), cinnamaldehyde (CIN) and ...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2019.08.003
更新日期:2019-12-01 00:00:00
abstract::One hundred and twenty-five samples were collected from eight different sites in the vicinity of Sanjay Gandhi National Park (SGNP) and screened for the presence of keratinophilic fungi using hair baiting technique for isolation. Seventy-three isolates were recovered and identified. The cultures were identified using ...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2014.08.004
更新日期:2014-12-01 00:00:00
abstract::The growing trends of emergence of antifungal-resistant Candida strains has recently been inspired the researchers to design new antifungal agents with novel mechanisms of action. Glabridin is an originally natural substrate with multiple biological activities which propose it as a novel anticancer, antimicrobial and ...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2017.05.002
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Rhizopus microsporus is one of the main causative agents of mucormycosis. These mycoses are mostly described as isolated cases involving uncontrolled diabetes mellitus or immunosuppressed patients. In this work we report a nosocomial outbreak of mucormycosis due to R. microsporum involving three young immuno...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2018.09.002
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the antibiofilm activity of coumarin against Candida albicans. METHODS:The efficacy of coumarin against biofilm formation and the mature biofilm of C. albicans was quantified by crystal violet (CV) staining and the 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenyla...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2018.12.003
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE OF THE STUDY:Candidiasis and dermatophytoses are benign infections in humans and animals, but they are very dreaded diseases in immunocompromised individuals. These infections become resistant to different treatments which make them more dangerous. In this work, we tried to find a new way for treating them. S...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2018.06.003
更新日期:2018-09-01 00:00:00
abstract::To study invasive pulmonary Aspergillosis (IPA), we depleted neutrophils in mice using the monoclonal antibody anti-Gr-1/Ly-6G. Immunocompetent and neutropenic mice were infected via intratracheal with conidia of Aspergillus fumigatus clinical isolates, characterized as either higher or lower elastase producers. Neutr...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2018.10.003
更新日期:2019-06-01 00:00:00
abstract::Three chalcones, 2'-hydroxy-4,4',6'-trimethoxychalcone, 2'-hydroxy-4,4',6'-tetramethoxychalcone, and 3,2'-dihydroxy-4,4',6'-trimethoxychalcone, were isolated from the leaves of Piper hispidum in a bioguided fractionation of crude extract. The antimicrobial activity of crude extract of P. hispidum leaves was determined...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2016.03.002
更新日期:2016-09-01 00:00:00
abstract::Candida spp. is a common cause of invasive fungal disease. The aim of this study was to examine the susceptibility of Candida spp. to fluconazole, itraconazole and voriconazole and explore the correlation between triazoles susceptibility. The antifungal susceptibility in the present study was measured by ATB Fungus 3 ...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2018.03.005
更新日期:2018-06-01 00:00:00
abstract::Emericella nidulans is a species that has only rarely been implicated in human disease after cataract surgery. Here, we report the first postoperative case in the literature, as far as we know. The patient was a 50-year-old patient presented with mild anterior uveitis one week after cataract surgery, and hypopion deve...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2015.12.010
更新日期:2016-09-01 00:00:00
abstract::In Algeria, many bacterial biofilms have been studied but those of fungal origin, particularly those due to the yeast Candida albicans remained unidentified. The present study was performed at the Chabane Hamdoune hospital in Maghnia (Algeria), where 51 strains of C. albicans representing 16.94% of all taken samples w...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2011.07.006
更新日期:2011-09-01 00:00:00
abstract::Saksenaea vasiformis is an emerging human pathogen, belonging to the order Mucorales of the subphylum Mucormycotina, most often associated with rhino-cerebral, cutaneous and subcutaneous infections following trauma. A review of the published literature was attempted on the occasion of a cutaneous leg infection with fa...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章,评审
doi:10.1016/j.mycmed.2019.06.005
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:In this paper, we describe the preparation and synthesis of several enynediesters, conjugated diynes and acetylenic compounds from starting materials comprising one hydroxyl and one acetylenyl group and their antifungal activity. MATERIALS AND METHODS:For synthesis of the compounds, a combined solution of N,...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2012.06.001
更新日期:2012-09-01 00:00:00
abstract:INTRODUCTION:Airborne fungi are considered important causes of respiratory allergy and diseases. The knowledge of these fungi in a city or region is important for the ecological diagnosis and specific treatment of respiratory manifestations induced by inhalation of fungal agents. Therefore, in recent years bioaerosols ...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2017.12.002
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:This study aimed at providing original data on fungemia in the Centre Hospitalier de Mayotte in terms of prevalence, epidemiological characteristics of infected patients, yeast species distribution and profile of in vitro antifungals susceptibility. METHODS:A total of 223 positive blood cultures for yeasts w...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2020.101081
更新日期:2020-11-18 00:00:00
abstract:INTRODUCTION:Comparing the activities of secreted enzymes in different fungal species can improve our understanding of their pathogenic role. Secretion of various enzymes by Candida species has been considered for determination of their virulence in different Candida infections including vulvovaginitis. AIMS:The aim o...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2017.01.009
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:The lack of data concerning the mycological spectrum of onychomycosis in Cameroon prompted us to conduct the present study, which aimed to determine the mycological profile of onychomycosis diagnosed during dermatologic consultations in Yaoundé, Cameroon. METHODS:This was a cross-sectional study held from O...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2017.03.002
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:The increasing importance of dermatophytoses and emerging resistance of dermatophytes to current synthetic antifungals have stimulated the search for safer and more effective alternative drugs from natural sources. The present study was carried out to identify antagonistic bacteria of soil origin with strong ...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2014.01.117
更新日期:2014-06-01 00:00:00
abstract::Candida nivariensis is a cryptic fungal species classified within the Candida glabrata complex. It was described for the first time in 2005 by the means of DNA sequencing. We report a rare case of C. nivariensis deep-seated infection occurring in a 77-year-old man hospitalized for cysto-prostatectomy. Phenotypic testi...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章,评审
doi:10.1016/j.mycmed.2020.101042
更新日期:2020-12-01 00:00:00
abstract::Fusarium onychomycosis is not uncommon in tropical countries but is worth reporting. We report a case of nondermatophytic onychomycosis by Fusarium oxysporum in an immunocompetent woman from Buldhana district of Maharashtra (India). Bilateral involvement of great toe nail, chronic duration and acquisition of infection...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2015.12.003
更新日期:2016-03-01 00:00:00
abstract::Tineabarbae is a rare form of dermatophytosis that affects hair follicles of the beard and moustache. Dermoscopy could prove useful to identify parasitism of hair of the beard, just as it has proven useful in the diagnosis of Tineacapitis. We present the first fully documented case series of T. barbae with clinical, d...
journal_title:Journal de mycologie medicale
pub_type:
doi:10.1016/j.mycmed.2020.101104
更新日期:2020-12-15 00:00:00
abstract::Curvularia lunata is a dematiaceous fungus that rarely causes cutaneous infections in immunocompetent humans. We describe a case of mycetoma pedis caused by Curvularia lunata in a 50-year-old woman from a rural farming community who had prolonged morbidity due to diagnostic delay. She improved with antifungal therapy,...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2013.09.005
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:In the present investigation, the Morus alba (M. alba), Vitis vinifera (V. vinifera), Ficus religiosa (F. religiosa) and Citrus paradisi (C. paradisi) leaves anti-aflatoxigenic activities were evaluated in Aspergillus flavus (A. flavus) inoculated feed. METHODS:The broiler feed inoculated with A. flavus was...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2017.03.003
更新日期:2017-09-01 00:00:00
abstract::In the end of May 2012, a meeting of the group "sérodiagnostic fongique" of the "Société française de mycologie médicale" had concerned quality controls to use, in particular, in the follow-up of Elisa techniques. A preliminary investigation showed that the internal quality controls (CIQ), according to the terms defin...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2012.11.001
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:The effect of candidemia on immunologic parameters in breast tumor bearing patients is not well studied. Here, we hypothesised that candidemia in the tumor background may change the outcome of immunologic parameters and tumor condition. METHOD:Mice were divided into four groups, including normal, tumor, Cand...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2018.10.006
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Vulvovaginal candidiasis (VVC) is the most prevalent vaginitis in women, accounting for 10 million medical referrals a year. Vaginal clotrimazole is a drug of choice for VVC treatment. However, increased drug resistance to this microorganism has led to an interest in naturally derived antifunga...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.mycmed.2017.07.003
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To check the oral colonization in neonates at high-risk and to associate these cases with candidemia. SUBJECTS AND METHODS:This study was conducted in the NICU. For six months, 125 high-risk neonates were investigated for oral colonization and septicemia by yeasts. From this total, 19 neonates had yeasts on ...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2013.11.004
更新日期:2014-06-01 00:00:00
abstract:INTRODUCTION:Definition, diagnosis and treatment of allergic fungal sinusitis remain difficult and controversial despite the increasing number of publications. We report a case of an allergic fungal sinusitis with a review of the literature. CLINICAL CASE:A 45-year-old man consulted for sinusal polyposis resistant to ...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章,评审
doi:10.1016/j.mycmed.2015.09.007
更新日期:2015-12-01 00:00:00
abstract::Dermatophytes are responsible for widespread superficial fungal infections, currently representing a real public health problem. Some of the fungi involved in these mycoses are transmitted by pets, illustrating great host specificity within this fungal group. Thus, a new variety of zoophilic dermatophyte has been desc...
journal_title:Journal de mycologie medicale
pub_type: 杂志文章
doi:10.1016/j.mycmed.2016.05.005
更新日期:2016-09-01 00:00:00