Analysis of the role of Hsp25 phosphorylation reveals the importance of the oligomerization state of this small heat shock protein in its protective function against TNFalpha- and hydrogen peroxide-induced cell death.

abstract：:Circular RNAs (circRNAs) are a newly validated type of noncoding RNAs recently found to be deregulated in several human cancers. More accurate and specific noninvasive biomarkers are strongly needed for better diagnosis and prognosis of hepatocellular carcinoma (HCC). We performed a bioinformatics analysis to retrieve...

journal_title：Journal of cellular biochemistry

authors： Matboli M,Shafei AE,Ali MA,Ashry AM,Kamal KM,Agag MA,Reda I,Tash EF,Ali M

更新日期：2018-11-13 00:00:00

abstract：:Rabbit lymphocytes exposed to hyposmotic media first swell and then recover their initial volume within 6 min. During volume recovery, free amino acids (FAA) decrease from 451.1 to 208 nmoles/mg protein. Taurine was the dominating FAA, accounting for 70% of the FAA pool. The time course of 3H-taurine release induced b...

journal_title：Journal of cellular biochemistry

authors： Jesuś García J,Sánchez Olea R,Pasantes-Morales H

更新日期：1991-02-01 00:00:00

abstract：:Multiple studies demonstrated that early growth response factor 1 (EGR1) induces myocardial damage after acute myocardial infarction (AMI). Recent evidence indicates that microRNAs (miRNA) play an important role in exosome-mediated cardioprotection after AMI. Bioinformatics analysis has shown that miR-146a can regulat...

journal_title：Journal of cellular biochemistry

authors： Pan J,Alimujiang M,Chen Q,Shi H,Luo X

更新日期：2019-03-01 00:00:00

abstract：:Solar ultraviolet light (sUV) has been shown to promote the development of skin disorders including inflammation, photoaging, and skin carcinogenesis. Osajin is the major bioactive isoflavone present in the fruit of Maclura pomifera, commonly referred to as the Osage orange. In this study, we observed that osajin inhi...

journal_title：Journal of cellular biochemistry

authors： Kim JE,Heo YS,Lee KW

更新日期：2017-11-01 00:00:00

abstract：:Diabetic retinopathy (DR) is a leading cause of adult visual impairment and loss. This study aims to explore the effects of microRNA-9 (miR-9) on retinal neovascularization during DR by targeting the vascular endothelial growth factor A (VEGFA). DR rat models were successfully established. Retinal microvascular endoth...

journal_title：Journal of cellular biochemistry

authors： Liu WL

更新日期：2018-11-28 00:00:00

abstract：:Lysozyme is expressed in serous, but not mucous, cells of the tracheobronchial glands and thereby constitutes a marker of the serous cell lineage in these glands. To identify DNA regulatory elements and transcription factors mediating the commitment of progenitor cells to the serous cell lineage, we have characterized...

journal_title：Journal of cellular biochemistry

authors： Kai H,Takeuchi K,Ohmori H,Li JD,Gallup M,Basbaum C

更新日期：1996-06-01 00:00:00

abstract：:Inflammation in vascular (mostly arterial) walls and heart valves triggered by the trans-endothelial influx of LDL particles and the action of subsequently modified (e.g., by oxidation) LDL particles can trigger true bone formation by valvar fibroblasts, by a subpopulation of re-differentiation-competent VSMCs (vascul...

journal_title：Journal of cellular biochemistry

authors： Whitfield JF

更新日期：2005-06-01 00:00:00

abstract：:Heme oxygenase (HO-1) is a stress protein that has been suggested to participate in defense mechanisms against agents that induce oxidative injury such as hemoglobin/heme, hypoxia-ischemia and cytokines. Overexpression of HO-1 in endothelial cells (EC) might, therefore, protect against oxidative stress produced under ...

journal_title：Journal of cellular biochemistry

authors： Deramaudt BM,Braunstein S,Remy P,Abraham NG

更新日期：1998-01-01 00:00:00

abstract：:Pancreatic AR42J cells have the feature of pluripotency of the precursor cells of the gut endoderm. Betacellulin (BTC) and activin A (Act) convert them into insulin-secreting cells. Using mRNA differential display techniques, we have identified a novel mitochondrial transporter, which is highly expressed during the co...

journal_title：Journal of cellular biochemistry

authors： Yoshikumi Y,Mashima H,Ueda N,Ohno H,Suzuki J,Tanaka S,Hayashi M,Sekine N,Ohnishi H,Yasuda H,Iiri T,Omata M,Fujita T,Kojima I

更新日期：2005-08-15 00:00:00

abstract：:Knowledge of the rapidly developing hierarchy of controls affecting vascular development in placenta is required to understand how the growth factors and their receptor-mediated signals actually produce vessels. At the cell biological level, these events clearly require stable interactions between the cells, and cells...

journal_title：Journal of cellular biochemistry

authors： Rajashekhar G,Loganath A,Roy AC,Chong SS,Wong YC

更新日期：2005-09-01 00:00:00

abstract：:The differentiation therapy in treatment of acute promyelocytic leukemia (APL), based on the administration of all-trans retinoic acid (ATRA), is currently flanked with the use of As2O3, a safe and effective agent for patients showing a resistance to ATRA treatment. A synergy between ATRA and As3O3 was also reported i...

journal_title：Journal of cellular biochemistry

authors： Brugnoli F,Bovolenta M,Benedusi M,Miscia S,Capitani S,Bertagnolo V

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:Endometrial carcinoma (EC), a common gynecological malignancy with high incidence, affects the mental and physical health of women. Mounting evidence shows that long noncoding RNAs (lncRNAs), messenger RNAs (mRNAs), and microRNAs (miRNAs) have instrumental roles in various biological processes associated with t...

journal_title：Journal of cellular biochemistry

authors： Zhao D,Ren C,Yao Y,Wang Q,Li F,Li Y,Jiang A,Wang G

更新日期：2020-03-01 00:00:00

abstract：:We previously reported that prostaglandin F2 alpha (PGF2 alpha) receptor is coupled to pertussis toxin (PTX)-sensitive GTP-binding protein (G protein) in osteoblast-like MC3T3-E1 cells [Miwa et al. (1990): Biochem Biophys Res Commun 171:1229-1235]. In the present study, we examined the effect of PGF2 alpha on the acti...

journal_title：Journal of cellular biochemistry

authors： Kozawa O,Suzuki A,Kotoyori J,Tokuda H,Watanabe Y,Ito Y,Oiso Y

更新日期：1994-07-01 00:00:00

abstract：:Wedelolactone is an herbal medicine that is used to treat septic shock, hepatitis and venom poisoning. Although in differentiated and cancer cells, wedelolactone has been identified as anti-inflammatory, growth inhibitory, and pro-apoptotic, the effects of wedelolactone on stem cell differentiation remain largely unkn...

journal_title：Journal of cellular biochemistry

authors： Lim S,Jang HJ,Park EH,Kim JK,Kim JM,Kim EK,Yea K,Kim YH,Lee-Kwon W,Ryu SH,Suh PG

更新日期：2012-11-01 00:00:00

abstract：:The microenvironment of the cancer cell is pivotal to its phenotypic regulation. One of the central components of the microenvironment is temperature. An elevation in environmental temperature has been shown to increase the cancer cell's susceptibility to chemo- and radiation therapy. The goal of the studies described...

journal_title：Journal of cellular biochemistry

authors： Zeng Y,Kulkarni P,Inoue T,Getzenberg RH

更新日期：2009-05-01 00:00:00

abstract：:Coupling factor 6 (CF6) forces a counter-clockwise rotation of plasma membrane F1 Fo complex, resulting in proton import and accelerated aging. Inhibitory factor peptide 1 (IF1) suppresses a unidirectional counter-clockwise rotation of F1 Fo complex without affecting ATP synthesis. We tested the hypothesis that IF1 ma...

journal_title：Journal of cellular biochemistry

authors： Osanai T,Tanaka M,Mikami K,Kitajima M,Magota K,Tomita H,Okumura K

更新日期：2018-07-01 00:00:00

abstract：:We examined the effects of photobiomodulation (PBM) independently and combined with curcumin on stereological parameters and basic fibroblast growth factor (bFGF), hypoxia-inducible factor-1α (HIF-1α), and stromal cell-derived factor-1α (SDF-1α) gene expressions in an excisional wound model of rats with type one diabe...

journal_title：Journal of cellular biochemistry

authors： Amini A,Soleimani H,Abdollhifar MA,Moradi A,Ghoreishi SK,Chien S,Bayat M

更新日期：2019-10-01 00:00:00

abstract：:Recent studies demonstrate that reactive oxygen species (ROS) are important mediators of acute pancreatitis, whether induced experimentally or in necrotizing pancreatitis in humans; however, the cellular processes involved remain unclear. Adapter protein CrkII, plays a central role for convergence of cellular signals ...

journal_title：Journal of cellular biochemistry

authors： Andreolotti AG,Bragado MJ,Tapia JA,Jensen RT,Garcia-Marin LJ

更新日期：2006-02-01 00:00:00

abstract：:Antibodies against pure discoidin I have been used as a tool to ascertain the role of this lectin in aggregation of Dictyostelium discoideum. Discoidin I is widely expressed over the cell surface of aggregation-competent AX-2 cells, as ascertained by indirect immunofluorescence with specific (antidiscoidin I) antibodi...

journal_title：Journal of cellular biochemistry

authors： Cano A,Pestaña A

更新日期：1984-01-01 00:00:00

abstract：:Growing evidence has shown that a large number of miRNAs are abnormally expressed in cervical cancer (CC) tissues and play irreplaceable roles in tumorigenesis, progression, and metastasis. This study aimed to identify new biomarkers and pivotal genes associated with CC prognosis through comprehensive bioinformatics a...

journal_title：Journal of cellular biochemistry

authors： Gao C,Zhou C,Zhuang J,Liu L,Liu C,Li H,Liu G,Wei J,Sun C

更新日期：2018-08-01 00:00:00

abstract：:Signal transducer and activator of transcription 3 (STAT3) was reported to be involved in adipogenesis. However, the regulating mechanism of STAT3 remains unclear. The present results showed that STAT3 was activated within 2-h adipogenic induction, in which the phosphorylated STAT3 translocated from cytoplasm to the n...

journal_title：Journal of cellular biochemistry

authors： Zhang K,Guo W,Yang Y,Wu J

更新日期：2011-02-01 00:00:00

abstract：:L-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) are adhesion molecules that play critical roles in neutrophil rolling during inflammation and lymphocyte homing. On the other hand they also function as signaling receptors to induce cytoskeleton changes. The present study is to investigate the signaling kinases...

journal_title：Journal of cellular biochemistry

authors： Luo J,Xu T,Wang X,Ba X,Feng X,Deepak V,Zeng X

更新日期：2010-07-01 00:00:00

abstract：:Copy number variation (CNV) and abnormal expression of microRNAs (miRNAs) always lead to deregulation of genes in cancer, including gastric cancer (GC). However, little is known about how CNVs affect the expression of miRNAs. By integrating CNV and miRNA profiles in the same samples, we identified eight miRNAs (miR-12...

journal_title：Journal of cellular biochemistry

authors： An J,Pan Y,Yan Z,Li W,Cui J,Yuan J,Tian L,Xing R,Lu Y

更新日期：2013-09-01 00:00:00

abstract：:SCN- binds to the charged amino group of lysines, inducing local changes in the electrostatic free energy of histones. We exploited this property to selectively perturb the histone-DNA interactions involved in the stabilization of eu and heterochromatin. Differential scanning calorimetry (DSC) was used as leading tech...

journal_title：Journal of cellular biochemistry

authors： Patrone E,Coradeghini R,Barboro P,D'Arrigo C,Mormino M,Parodi S,Balbi C

更新日期：2006-03-01 00:00:00

abstract：:APC and PTEN are tumor suppressor proteins that bind through their C-termini to the PDZ domain containing-hDlg scaffolding protein. We have found that co-expression of PTEN and hDlg enhanced the negative regulation of the PI3K/Akt pathway by PTEN, indicating the physiologic importance of these interactions. APC and PT...

journal_title：Journal of cellular biochemistry

authors： Sotelo NS,Valiente M,Gil A,Pulido R

更新日期：2012-08-01 00:00:00

abstract：:Phospholipase D (PLD) and ADP-ribosylation factor 6 (ARF6) have been implicated in vesicular trafficking and rearrangement of the actin cytoskeleton. We have explored the co-localization of rat PLD1b and rat PLD2 with wild type and mutant forms of ARF6 in HeLa cells and studied their activation by ARF6 and the role of...

journal_title：Journal of cellular biochemistry

authors： Hiroyama M,Exton JH

更新日期：2005-05-01 00:00:00

abstract：:The control of glucose uptake and glycogen metabolism by insulin in target organs is in part mediated through the regulation of protein-serine/threonine kinases. In this study, the expression and phosphotransferase activity levels of some of these kinases in rat heart ventricle were measured to investigate whether the...

journal_title：Journal of cellular biochemistry

authors： Kim SO,Hasham MI,Katz S,Pelech SL

更新日期：1998-12-01 00:00:00

abstract：:CD38 is a type II transmembrane glycoprotein found mainly on the plasma membrane involved in the metabolism of cADPR and NAADP, two nucleotides with calcium mobilizing activity independent of inositol trisphosphate. Recent data report the presence of CD38 in different cellular compartments raising new questions about ...

journal_title：Journal of cellular biochemistry

authors： Trubiani O,Guarnieri S,Eleuterio E,Di Giuseppe F,Orciani M,Angelucci S,Di Primio R

更新日期：2008-03-01 00:00:00

abstract：:Osteosarcoma cells are recognized by abnormal function that causes a primary bone tumor. Osteosarcoma cells U(2)OS and SAOS-2 were analyzed for the expression of cell surface markers. High expression was quantified for hyaloronidase receptor (CD-44) > moderate for integrins (CD-51 and -61), > and lower for selectins (...

journal_title：Journal of cellular biochemistry

authors： Benayahu D,Shur I,Marom R,Meller I,Issakov J

更新日期：2001-01-01 00:00:00

abstract：:Skin is a representative self-renewing tissue containing stem cells. Although many attempts have been made to define and isolate skin-derived stem cells, establishment of a simple and reliable isolation procedure remains a goal to be achieved. Here, we report the isolation of cells having stem cell properties from mou...

journal_title：Journal of cellular biochemistry

authors： Medina RJ,Kataoka K,Takaishi M,Miyazaki M,Huh NH

更新日期：2006-05-01 00:00:00