Abstract：
:While randomized, placebo-controlled double-blinded trials have become the pharmacological standard over the last 60 years, the gain in knowledge of the mechanisms behind the placebo response in recent years has raised substantial concerns about the appropriateness of some of its underlying assumptions. The following questions will be addressed: Is the assumed model of drug and placebo being additive (still) valid? Does the likelihood of receiving active treatment affect the placebo response? What is the size of the placebo response in "active comparator studies"? Minimizing the placebo response/maximizing the drug-placebo difference? How to maximize the placebo response in daily medicine? What is the placebo response with personalized medicines in the future? This and other questions require answers that can only be generated with more experimental studies on the placebo response and with thorough meta- and re-analyses of placebo responses in clinical trials.
journal_name
Complement Ther Medjournal_title
Complementary therapies in medicineauthors
Enck P,Klosterhalfen Sdoi
10.1016/j.ctim.2012.12.010subject
Has Abstractpub_date
2013-04-01 00:00:00pages
98-101issue
2eissn
0965-2299issn
1873-6963pii
S0965-2299(12)00176-8journal_volume
21pub_type
杂志文章abstract：BACKGROUND:Muscle damage induced by an acute bout of eccentric exercise results in transient arterial stiffening. In this study, we sought to determine the effects of progressive eccentric resistance exercise training on vascular functions, and whether herb supplementation would enhance training adaptation by ameliorat...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2016.10.003
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE:The goal of this study was to synthesize evidence regarding the efficacy of inhalation aromatherapy in patients undergoing cardiac surgery. METHODS:We conducted an electronic search of four authentic databases. Randomized controlled trials (RCTs), which compared inhalation aromatherapy versus control in pati...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,meta分析
doi：10.1016/j.ctim.2019.102256
更新日期：2020-01-01 00:00:00
abstract：INTRODUCTION:The World Health Organization has reported that approximately 35% of cancer-related deaths are attributed to modifiable risk factors. Among the most important risk factors amenable to modification are obesity and lack of physical activity. The purpose of this article is to review the current evidence of th...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ctim.2019.03.013
更新日期：2019-06-01 00:00:00
abstract：UNLABELLED:Back pain significantly affects both patients and society through personal suffering, supporting burden, work loss, and incurred expenses. With no unequivocal support for surgery versus conservative treatment, an integrative approach has become popular in Korea. OBJECTIVES:To investigate the outcomes of an ...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2010.02.003
更新日期：2010-04-01 00:00:00
abstract：:Traditional Chinese medicine (TCM) has long justified its practice on empirical phenomenology. Questions remain, however, as to the legitimacy of this approach and its relevance to TCM practice and educational developments in the 21st century. General medical practice (GMP) has used practice-based data collected over ...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ctim.2006.06.006
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:Merkel cell carcinoma (MCC) is a rare, aggressive, neuroendocrine skin tumor with frequent local recurrence, lymph node involvement, distant metastasis, and a high mortality rate. Viscum album extracts (VAE) are a widely used adjunct in cancer treatment and show cytotoxic and immune-modulating effects. CASE...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2018.04.001
更新日期：2018-06-01 00:00:00
abstract：:Ulcerative colitis (UC) is one of the inflammatory diseases of the gut with frequent bloody diarrhea leads to increased rates of anemia. Evidences indicate the immunomodulation disorders in the response to intestinal microbiota in UC. Although sugarcane molasses, rich in necessary minerals and vitamins, could be a goo...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2019.102210
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVE:To develop a simplified Tai Chi exercise program for frail older adults. DESIGN:For phase I, using a focus group, 40 frail Taiwanese older adults were interviewed to explore their viewpoints on Tai Chi and have been reported elsewhere. This paper emphasized on the phase II of the study in which the older adu...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2006.05.002
更新日期：2006-09-01 00:00:00
abstract：:Established in 2004, the Pediatric Complementary and Alternative Medicine Research & Education (PedCAM) Network (www.pedcam.ca) is a multidisciplinary national and international network focused on pediatric research and education with the vision of safe and effective use of complementary and alternative medicine (CAM)...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2011.03.002
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVES:(1) To replicate a study of the efficacy of Argentum nitricum 12X in the reduction of test anxiety as demonstrated previously. (2) To investigate the correlation between individuals identified to match the A. nitricum profile and the reduction of test anxiety. To compare traditionally prepared homeopathic A....
journal_title：Complementary therapies in medicine
pub_type： 临床试验,杂志文章
doi：10.1016/s0965-2299(03)00059-1
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:This was a secondary data analysis of a cluster-randomized clinical trial that tested the efficacy of a 20-week Sun-style Tai Chi (TC) program in reducing pain in community-dwelling elders with cognitive impairment and knee osteoarthritis (OA). The study also examined whether elders' level of cognitive functi...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2015.06.001
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:This is the first part of a larger spectrum systematic review which aims to identify and evaluates the effectiveness of all different non-pharmacological acupuncture techniques used for COPD. In this first publication, we describe the results of filiform needle acupuncture METHODS: Randomised controlled tria...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,meta分析
doi：10.1016/j.ctim.2019.08.016
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Scant research has been undertaken regarding chiropractors' skills and knowledge associated with evidence-based practice (EBP), and their perceived barriers to EBP. These issues appear to have been examined in only one small qualitative study and one small study of chiropractors holding orthopaedic diplomas....
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2014.02.007
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVES:To develop simplified constitutional indications for homeopathic medicines so that parents of children with recurrent upper respiratory tract infection (URTI) could choose homeopathic medicines for their children more "accurately", and to subsequently evaluate if these choices match the prescriptions of trai...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2004.09.004
更新日期：2004-06-01 00:00:00
abstract：:A custom-made questionnaire was sent to all UK medical charities in 1999 and again in 2002. Its primary aim was to assess the commitment of these institutions towards funding research in complementary and alternative medicine (CAM). Sixty-two (1999) and 60 (2002) answers were received corresponding to response rates o...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/s0965-2299(03)00061-x
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND AND AIMS:Colonoscopy can be painful and uncomfortable. Aromatherapy is often used for the relief of anxiety or discomfort. Recently, it has been reported that olfactory stimulation induces various physiological effects. We investigated the effects of aromatherapy on anxiety and abdominal discomfort during co...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2017.08.012
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVE:We report a case of congestive heart failure complicated by hospital-acquired pneumonia that was successfully treated with traditional Chinese medicine (TCM) and antibiotics. CLINICAL FEATURES AND OUTCOME:A 33-year-old man with a history of heart failure developed pneumonia during hospitalization. After the ...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2019.01.008
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:The aim of present study was to review and categorize the clinical trials investigating the clinical effects of different botanical parts of dates compared with any controls. METHODS:All clinical trials (randomized, pilot, quasi-experimental, cross-over. and non-randomized clinical trials) evaluating the clini...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2020.102429
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Despite several studies about the effects of saffron supplementation on serum concentrations of lipid and glucose profiles, no systematic study had summarized the findings. Therefore, we conduct current study to systematically summarize findings from studies about the effect of saffron supplementation on ser...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,meta分析
doi：10.1016/j.ctim.2019.07.017
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVES:To assess the value of bee products with respect to antiviral efficacy against herpes viruses. DESIGN:A systematic review was done using the JUSTfind System of the Justus-Liebig-University Gießen and Scopus. RESULTS:Three trials on honey and 6 trials on propolis were conducted. Each trial provided evidence...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2019.01.014
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVES:Rhodiola rosea extract is one of the most common herbal treatment for stress. Its mechanism of action in humans still need to be determined. We investigated the effect of a single dose intake of Rhodiola rosea extract on the plastic after-effects induced by anodal and cathodal motor cortex transcranial Direc...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2018.09.013
更新日期：2018-12-01 00:00:00
abstract：:WHO Traditional Medicine Strategy 2014-23 recommended evidence-based healthcare (EBHC) education for traditional and complementary medicine (T&CM) professionals, including Chinese medicine practitioners (CMPs). We evaluated the impact of a customized educational workshop on Hong Kong CMPs' knowledge, attitude and prac...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2019.05.004
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:Our goal in this study aims to explain the polypharmacological mechanism at the molecular level responsible for the effectiveness of a traditional Chinese medicine (TCM) prescription FTZ to treat hyperlipidemia and related disease. DESIGN:By MDL(®) ISIS_Base 2.5, we constructed a compound database based on t...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2014.08.002
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVES:This pilot study examined the potential efficacy of cranial electric stimulation for the treatment of insomnia. DESIGN:The researchers tested the hypothesis through a randomized, double-blind, and placebo controlled clinical trial. The researchers approached eligible subjects who scored 21 or above on the P...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2012.11.007
更新日期：2013-02-01 00:00:00
abstract：OBJECTIVES:To examine the long-term effects of foot-bathing therapy, using different water temperatures, on the sleep quality of older adults living in nursing homes. DESIGN:A quasi-experimental study design with non-equivalent control group. SETTINGS:Thirty participants were recruited from a nursing home in Gyeong-g...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2016.02.005
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:This study examined whether people thought neurotics were more likely to 'get better' when using CAM rather than orthodox medicine. DESIGN:A total of 165 participants completed a four part questionnaire, in which they were required to read eight vignettes (each about 70 words long) describing a British male ...
journal_title：Complementary therapies in medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1054/ctim.2000.0381
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVES:To report on the potential effectiveness of hypocaloric, plant-based short-term dietary oatmeal interventions in the treatment of insulin resistance in critically ill patients on the intensive care unit. CLINICAL FEATURES AND OUTCOME:A 67-year-old female with type 2 diabetes was admitted to our hospital wit...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2019.07.019
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Complementary and alternative medicine (CAM) use is increasingly popular amongst general populations around the world with women constituting substantial CAM users. However, self-prescribed CAM use does raise potential safety concerns and so it is important to identify those risk factors associated with self...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2015.06.011
更新日期：2015-10-01 00:00:00
abstract：OBJECTIVES:The physiological changes that occur during pregnancy, including increased blood volume and cardiac output, can affect hemodynamic control, most profoundly with positional changes that affect venous return to the heart. By using Osteopathic Manipulative Treatment (OMT), a body-based modality theorized to aff...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ctim.2013.08.008
更新日期：2013-12-01 00:00:00
abstract：AIM:To clarify the reasons underlying people's use of medical herbalism in the context of contemporary U.K. health care. DESIGN:This qualitative, interpretative study recruited 19 adults who were consulting with registered medical herbalists in a region of southern England. Participants were interviewed about their ex...
journal_title：Complementary therapies in medicine
pub_type： 杂志文章
doi：10.1016/j.ctim.2009.08.001
更新日期：2009-10-01 00:00:00
