Enzyme catalysed tandem reactions.


:To transfer to the laboratory, the excellent efficiency shown by enzymes in Nature, biocatalysis, had to mimic several synthetic strategies used by the living organisms. Biosynthetic pathways are examples of tandem catalysis and may be assimilated in the biocatalysis field for the use of isolated multi-enzyme systems in the homogeneous phase. The concurrent action of several enzymes that work sequentially presents extraordinary advantages from the synthetic point of view, since it permits a reversible process to become irreversible, to shift the equilibrium reaction in such a way that enantiopure compounds can be obtained from prochiral or racemic substrates, reduce or eliminate problems due to product inhibition or prevent the shortage of substrates by dilution or degradation in the bulk media, etc. In this review we want to illustrate the developments of recent studies involving in vitro multi-enzyme reactions for the synthesis of different classes of organic compounds.


Curr Opin Chem Biol


Oroz-Guinea I,García-Junceda E




Has Abstract


2013-04-01 00:00:00














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    authors: Cargill JF,Lebl M

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    authors: You Y

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    authors: Chilkoti A,Christensen T,MacKay JA

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    authors: Min DH,Mrksich M

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    authors: Berkessel A

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  • Helical peptide and protein design.

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    pub_type: 杂志文章,评审


    authors: Marsden BD,Knapp S

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    pub_type: 杂志文章,评审


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    authors: Behrouzian B,Buist PH

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    authors: Sečkutė J,Devaraj NK

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  • Mechanisms employed by cellulase systems to gain access through the complex architecture of lignocellulosic substrates.

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    authors: Perry MJ,Higgs GA

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    authors: Schmitt EK,Moore CM,Krastel P,Petersen F

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  • Marine bioinorganic materials: mussels pumping iron.

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    pub_type: 杂志文章,评审


    authors: Wilker JJ

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    journal_title:Current opinion in chemical biology

    pub_type: 杂志文章,评审


    authors: Zhou JZ

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  • Vanadium haloperoxidases.

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    pub_type: 杂志文章,评审


    authors: Butler A

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    pub_type: 杂志文章,评审


    authors: Kluge AF,Petter RC

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  • Mechanistic advances in plant natural product enzymes.

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    journal_title:Current opinion in chemical biology

    pub_type: 杂志文章,评审


    authors: Usera AR,O'Connor SE

    更新日期:2009-10-01 00:00:00