Invited commentary: is prenatal fasting during Ramadan related to adult health outcomes? A novel and important question for epidemiology.


:In this issue of the Journal, Van Ewijk et al. (Am J Epidemiol. 2013;177(8):729-736) report intriguing associations between prenatal exposure to the religious month of Ramadan and body anthropometry among adult Muslims in Indonesia. They categorized prenatal exposure according to the relative timing of Ramadan and the individual's birth date. Because the data were derived from a study of adults, they could not determine whether an individual's mother had fasted during Ramadan or not. Therefore, they used an intention-to-treat analysis to compare the outcomes for groups categorized as unexposed with the outcomes for groups categorized as exposed during specified periods of gestation. Periconceptional exposure to Ramadan was associated with a 0.8-cm reduction in average adult height. Exposure in mid- or late gestation was associated with slightly lower adult weight. We address 5 questions raised by this study: 1) Can Ramadan fasting be considered a mild form of acute starvation?; 2) Are the findings consistent with other knowledge about prenatal nutrition and offspring outcomes?; 3) Are there other explanations for the associations that were found?; 4) Are the results internally coherent and robust enough to support the 2 main findings?; and 5) What strategies could be used to further advance this important field of research?


Am J Epidemiol


Susser E,Ananth CV




Has Abstract


2013-04-15 00:00:00














  • Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: mortality.

    abstract::Stroke, coronary heart disease (CHD) and total mortality are evaluated from death certificates in enumerated cohorts of 45-64-year old Japanese men in Hiroshima and Nagasaki (1965-1970), in Homolulu (1966-1970), and in the San Francisco area (1968-1972). Total mortality is highest in Japan with no consistent differenc...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Worth RM,Kato H,Rhoads GG,Kagan K,Syme SL

    更新日期:1975-12-01 00:00:00

  • Invited Commentary: Rethinking Cervical Cancer Elimination in Terms of Lifetime Risk Rather Than Arbitrarily-Defined Age-Standardized Incidence Rates.

    abstract::Vänskä et al. (Am J Epidemiol. XXXX;XXX(XX):XXXX-XXXX)) provide us with cohort lifetime risks of cervical cancer attributable to different human papillomavirus (HPV) types in Sweden. We argue that a standardized lifetime risk such as those calculated by Vänskä et al. might be a more appropriate public health target fo...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Malagón T,Franco EL

    更新日期:2020-07-08 00:00:00

  • Serum dioxin and immunologic response in veterans of Operation Ranch Hand.

    abstract::The authors studied immune response and exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin) among veterans of Operation Ranch Hand, the US Air Force unit responsible for the aerial spraying of herbicides in Vietnam from 1962 to 1971. A comparison group of Air Force veterans who served in Southeast Asia but were n...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Michalek JE,Ketchum NS,Check IJ

    更新日期:1999-06-01 00:00:00

  • Depressive symptoms and headaches in relation to proximity of residence to an alternating-current transmission line right-of-way.

    abstract::Electric power transmission lines have become objects of public controversy. Hypotheses have linked neurobehavioral effects to the electric and magnetic fields that these lines produce. The authors conducted a telephone interview survey in November 1987 to assess the prevalence of depressive symptoms and headache in r...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Poole C,Kavet R,Funch DP,Donelan K,Charry JM,Dreyer NA

    更新日期:1993-02-01 00:00:00

  • Sex-specific associations of magnetic resonance imaging-derived intra-abdominal and subcutaneous fat areas with conventional anthropometric indices. The Atherosclerosis Risk in Communities Study.

    abstract::Accurate measurement of central fat patterning is difficult to obtain by conventional anthropometry. Direct measurement of intra-abdominal fat area by magnetic resonance imaging, while accurate, is impractical for large-scale observational studies. This report examines the sex-specific associations of conventional ant...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Schreiner PJ,Terry JG,Evans GW,Hinson WH,Crouse JR 3rd,Heiss G

    更新日期:1996-08-15 00:00:00

  • Who is more affected by ozone pollution? A systematic review and meta-analysis.

    abstract::Ozone is associated with adverse health; however, less is known about vulnerable/sensitive populations, which we refer to as sensitive populations. We systematically reviewed epidemiologic evidence (1988-2013) regarding sensitivity to mortality or hospital admission from short-term ozone exposure. We performed meta-an...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,meta分析,评审


    authors: Bell ML,Zanobetti A,Dominici F

    更新日期:2014-07-01 00:00:00

  • Viral hepatitis: enzyme assays and serologic procedures in the study of an epidemic.

    abstract::An epidemic of viral hepatitis beginning in late 1975 in a residence for multiply handicapped children, recognized very early in its course, was investigated prospectively to permit comparison of enzymatic and serologic tests. Thirty-three residents of the institution and 46 full- and part-time employees were studied ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Rakela J,Nugent E,Mosley JW

    更新日期:1977-12-01 00:00:00

  • Low dehydroepiandrosterone and ischemic heart disease in middle-aged men: prospective results from the Massachusetts Male Aging Study.

    abstract::The adrenal steroid dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) have been characterized as "protective" against ischemic heart disease (IHD), especially in men, on the basis of sparse epidemiologic evidence. The authors used data from the Massachusetts Male Aging Study, a random sample prospective study of 1...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Feldman HA,Johannes CB,Araujo AB,Mohr BA,Longcope C,McKinlay JB

    更新日期:2001-01-01 00:00:00

  • Capture-recapture and multiple-record systems estimation I: History and theoretical development. International Working Group for Disease Monitoring and Forecasting.

    abstract::This paper reviews the historical background and the theoretical development of models for the analysis of data from capture-recapture or multiple-record systems for estimating the size of closed populations. The models and methods were originally developed for use in fisheries and wildlife biology and were later adap...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,评审



    更新日期:1995-11-15 00:00:00

  • International analysis of insulin-dependent diabetes mellitus mortality: a preventable mortality perspective. The Diabetes Epidemiology Research International (DERI) Study.

    abstract::Differential survival associated with insulin-dependent diabetes mellitus (IDDM) was evaluated in a cross-country study using four population-based IDDM cohorts from Japan (n = 1,374), Israel (n = 610), Allegheny County, Pennsylvania (n = 995), and Finland (n = 5,144). For the purpose of this cross-country comparison,...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章



    更新日期:1995-09-15 00:00:00

  • Epidemiology of invasive Streptococcus pneumoniae among Navajo children in the era before use of conjugate pneumococcal vaccines, 1989-1996.

    abstract::Streptococcus pneumoniae is the most common cause of invasive bacterial disease among children worldwide. The authors aimed to determine the incidence, clinical characteristics, and serotype distribution of invasive pneumococcal disease (IPD) among Navajo children in the southwestern United States. Active population-b...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: O'Brien KL,Shaw J,Weatherholtz R,Reid R,Watt J,Croll J,Dagan R,Parkinson AJ,Santosham M

    更新日期:2004-08-01 00:00:00

  • Factors associated with functional decline and improvement in a very elderly community-dwelling population.

    abstract::The objective of this study was to analyze the factors associated with functional decline and improvement in a community-dwelling population of people aged 75 years and older. A representative sample of elderly people living at home in the city of Sherbrooke (Quebec, Canada) was assessed yearly on three occasions (199...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Hébert R,Brayne C,Spiegelhalter D

    更新日期:1999-09-01 00:00:00

  • Chemical correlates of pathogenicity of oils related to the toxic oil syndrome epidemic in Spain.

    abstract::The identity of the etiologic agent that caused the 1981 epidemic of toxic oil syndrome in Spain has not been established, and toxicologic study of oil specimens from the outbreak has been hampered by uncertainty about which oils were actually capable of causing illness. To identify chemical characteristics associated...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Kilbourne EM,Bernert JT Jr,Posada de la Paz M,Hill RH Jr,Abaitua Borda I,Kilbourne BW,Zack MM

    更新日期:1988-06-01 00:00:00

  • Estimation of the standardized risk difference and ratio in a competing risks framework: application to injection drug use and progression to AIDS after initiation of antiretroviral therapy.

    abstract::There are few published examples of absolute risk estimated from epidemiologic data subject to censoring and competing risks with adjustment for multiple confounders. We present an example estimating the effect of injection drug use on 6-year risk of acquired immunodeficiency syndrome (AIDS) after initiation of combin...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究


    authors: Cole SR,Lau B,Eron JJ,Brookhart MA,Kitahata MM,Martin JN,Mathews WC,Mugavero MJ,CNICS Research Network.

    更新日期:2015-02-15 00:00:00

  • Boys from populations with high-carbohydrate intake have higher fasting triglyceride levels than boys from populations with high-fat intake.

    abstract::Experimentally, high-carbohydrate diets have been shown to elevate triglycerides, but it has not been established whether this rise is permanent or transient. The authors approached this question by studying 719 boys from worldwide populations with marked differences in long-term carbohydrate intake. Fasting serum tri...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: West CE,Sullivan DR,Katan MB,Halferkamps IL,van der Torre HW

    更新日期:1990-02-01 00:00:00

  • Methods for pooling results of epidemiologic studies: the Pooling Project of Prospective Studies of Diet and Cancer.

    abstract::With the growing number of epidemiologic publications on the relation between dietary factors and cancer risk, pooled analyses that summarize results from multiple studies are becoming more common. Here, the authors describe the methods being used to summarize data on diet-cancer associations within the ongoing Poolin...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Smith-Warner SA,Spiegelman D,Ritz J,Albanes D,Beeson WL,Bernstein L,Berrino F,van den Brandt PA,Buring JE,Cho E,Colditz GA,Folsom AR,Freudenheim JL,Giovannucci E,Goldbohm RA,Graham S,Harnack L,Horn-Ross PL,Krogh V,L

    更新日期:2006-06-01 00:00:00

  • Weight variability effects: a prospective analysis from the Stanford Five-City Project.

    abstract::For determination of the effects of weight variability on cardiovascular risk factors, a random community sample of 269 men and 361 women aged 25-74 years, drawn from the Stanford Five-City Project, was followed for up to 10 years (1979-1989). Systolic and diastolic blood pressure, total and high density lipoprotein c...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Taylor CB,Jatulis DE,Fortmann SP,Kraemer HC

    更新日期:1995-03-01 00:00:00

  • Exercise During the First Trimester and Infant Size at Birth: Targeted Maximum Likelihood Estimation of the Causal Risk Difference.

    abstract::This cohort study sought to estimate the differences in risk of delivering infants who were small or large for gestational age (SGA or LGA, respectively) according to exercise during the first trimester of pregnancy (vs. no exercise) among 2,286 women receiving care at Kaiser Permanente Northern California in 2013-201...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Ehrlich SF,Neugebauer RS,Feng J,Hedderson MM,Ferrara A

    更新日期:2020-02-28 00:00:00

  • Depression and Incident HIV in Adolescent Girls and Young Women in HIV Prevention Trials Network 068: Targets for Prevention and Mediating Factors.

    abstract::The human immunodeficiency virus (HIV) epidemic among adolescent girls and young women (AGYW) in sub-Saharan Africa is a critical public health problem. We assessed whether depressive symptoms in AGYW were longitudinally associated with incident HIV, and identified potential social and behavioral mediators. Data came ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,随机对照试验


    authors: Goin DE,Pearson RM,Craske MG,Stein A,Pettifor A,Lippman SA,Kahn K,Neilands TB,Hamilton EL,Selin A,MacPhail C,Wagner RG,Gomez-Olive FX,Twine R,Hughes JP,Agyei Y,Laeyendecker O,Tollman S,Ahern J

    更新日期:2020-05-05 00:00:00

  • Selenium in diet, blood, and toenails in relation to breast cancer: a case-control study.

    abstract::The association between breast cancer and selenium, measured in the diet, plasma, erythrocytes, and toenails, was investigated in a case-control study in the Netherlands during 1985-1987. Dietary selenium intake was assessed by a structured dietary history technique among 133 breast cancer cases and 238 population con...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: van 't Veer P,van der Wielen RP,Kok FJ,Hermus RJ,Sturmans F

    更新日期:1990-06-01 00:00:00

  • Parainfluenzavirus upper respiratory tract illnesses in partially immune adult human subjects: a study at an Antarctic station.

    abstract::Outbreaks of respiratory tract illnesses (RTI) in adult humans during October and November 1975 at McMurdo Station, Antarctica, were investigated by viral isolation and serologic procedures. The recovery of viral agents was enhanced by use of cell cultures in the field. Recoveries of parainfluenzaviruses types 1 and 3...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Parkinson AJ,Muchmore HG,Scott LV,Kalmakoff J,Miles JA

    更新日期:1979-12-01 00:00:00

  • Magnesium in drinking water and death from acute myocardial infarction.

    abstract::The relation between death from acute myocardial infarction and the level of magnesium in drinking water was examined using mortality registers and a case-control design. The study area comprised 17 municipalities in the southern part of Sweden that have different magnesium levels in the drinking water. Cases were men...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Rubenowitz E,Axelsson G,Rylander R

    更新日期:1996-03-01 00:00:00

  • Relation of blood cadmium, lead, and mercury levels to biomarkers of lipid peroxidation in premenopausal women.

    abstract::Exposures to cadmium, lead, and mercury are associated with adverse health effects, including cardiovascular disease, which may be promoted by lipid peroxidation. The authors examined cadmium, lead, and mercury in relation to plasma levels of F(2)-8α isoprostanes (isoprostane), 9-hydroperoxy-10,12-octadecadienoic acid...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Pollack AZ,Schisterman EF,Goldman LR,Mumford SL,Perkins NJ,Bloom MS,Rudra CB,Browne RW,Wactawski-Wende J

    更新日期:2012-04-01 00:00:00

  • Epidemiologic study of Vibrio cholerae O1 and O139 in Thailand: at the advancing edge of the eighth pandemic.

    abstract::Vibrio cholerae O139 Bengal emerged on the Indian subcontinent in late 1992 and was first recognized in Thailand in 1993. To characterize the epidemiology of this disease, a hospital-based case-control study was conducted in Samutsakorn, a port city 30 km southwest of Bangkok. Between November 15, 1993, and June 3, 19...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Hoge CW,Bodhidatta L,Echeverria P,Deesuwan M,Kitporka P

    更新日期:1996-02-01 00:00:00

  • Longitudinal association of serum carotenoids and tocopherols with hostility: the CARDIA Study.

    abstract::Hostility is a personality trait associated with increased risk of coronary heart disease. No study has reported the association between hostility and antioxidants, which may be mediators for atherosclerosis. CARDIA (Coronary Artery Risk Development in Young Adults) Study participants were 3,579 men and women 18-30 ye...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究


    authors: Ohira T,Hozawa A,Iribarren C,Daviglus ML,Matthews KA,Gross MD,Jacobs DR Jr

    更新日期:2008-01-01 00:00:00

  • Epidemiology of cutaneous melanoma in the French West Indies (Martinique).

    abstract::The epidemiology of melanoma in populations of African-European descent has rarely been reported. The authors studied melanoma in the French West Indies (Martinique), where black Caribbeans and whites represented 96% and 4% of the population, respectively. Among the 85 cases of melanoma collected from 1976 to 1995, bl...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Garsaud P,Boisseau-Garsaud AM,Ossondo M,Azaloux H,Escarmant P,Mab GL,Zimmermann S,Saint-Cyr A,Quist D,Hélénon R,Jouannelle A

    更新日期:1998-01-01 00:00:00

  • Offspring birth weight and parental mortality: prospective observational study and meta-analysis.

    abstract::The authors have investigated associations between offspring size at birth and parental cardiovascular disease mortality among 12,086 mothers and 6,936 fathers of participants in the British 1958 birth cohort. Birth weight was inversely associated with all-cause mortality and cardiovascular mortality in both mothers a...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,meta分析,评审


    authors: Davey Smith G,Hyppönen E,Power C,Lawlor DA

    更新日期:2007-07-15 00:00:00

  • The use of logistic regression for modelling risk factors: with application to non-melanoma skin cancer.

    abstract::Logistic regression was used to estimate the "relative" risk of basal and squamous skin cancer for such factors as cumulative lifetime solar exposure, age, complexion, and tannability. In previous reports, a subject's exposure was estimated indirectly, by latitude, or by the number of sun days in a subject's habitat. ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Vitaliano PP

    更新日期:1978-11-01 00:00:00

  • Preterm delivery rates in North Carolina: are they really declining among non-Hispanic African Americans?

    abstract::The preterm delivery rate in North Carolina is consistently higher than the national average. However, recent reports suggest that singleton preterm delivery rates for non-Hispanic Whites are increasing while those for non-Hispanic African Americans are decreasing. To study this pattern further, the authors examined d...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Vahratian A,Buekens P,Bennett TA,Meyer RE,Kogan MD,Yu SM

    更新日期:2004-01-01 00:00:00

  • Lyme disease in outdoor workers: risk factors, preventive measures, and tick removal methods.

    abstract::A statewide cross-sectional study of risk factors for seropositivity for antibody to Borrelia burgdorferi in outdoor workers in New Jersey was performed in September and October 1988. The crude odds ratio associated with exposure to ticks on the primary state job was 2.2 (95% confidence interval (CI) 0.7-9.0). After a...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章


    authors: Schwartz BS,Goldstein MD

    更新日期:1990-05-01 00:00:00