When Schwann cells conspire with mitochondria, neighboring axons are under attack by glia-derived neurotoxic lipids.

Abstract:

:In this issue of Neuron, Viader et al. (2013) report on the production of toxic lipids by Schwann cells deficient in mitochondrial respiration, which are capable of destroying neighboring axons. This may have implications for understanding the neurobiology and treatment of mitochondrial neuropathies.

journal_name

Neuron

journal_title

Neuron

authors

Di Paolo G,Przedborski S

doi

10.1016/j.neuron.2013.02.016

subject

Has Abstract

pub_date

2013-03-06 00:00:00

pages

801-3

issue

5

eissn

0896-6273

issn

1097-4199

pii

S0896-6273(13)00174-8

journal_volume

77

pub_type

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