Etiological spectrum of symptomatic localization related epilepsies: a study from South India.


:Putative etiology was studied in 991 patients with symptomatic localization-related epilepsies seen in a university hospital in South India. They formed 39% of patients with various types of epilepsies and epileptic syndromes seen during the study period. Seizure occurred in close temporal association with an acute central nervous system (CNS) insult in 53% of patients. Infections of CNS including single CT enhancing lesion (SCTEL) accounted for 77% of patients with acute symptomatic epilepsy. Cerebrovascular diseases were the risk factors in 48% of patients with remote symptomatic epilepsy. Neurocysticercosis, SCTEL and small single cerebral calcific CT lesion (SSCCCTL) together accounted for 40% of etiological factors and neurotuberculosis for 10%. Infections of the central nervous system and SCTEL together were the putative risk factors in 52% of patients aged < or =40 years. Cerebrovascular diseases were the etiological factors in 64% of patients aged >40 years. Neurological handicaps from birth manifested by mental retardation and/or cerebral palsy was the feature in 21% of children. The type of seizure was either simple partial or complex partial with or without secondary generalization in 76% of patients. The remaining patients presented with either generalized tonic clonic seizures or unlocalized seizures. Localization to a single site of seizure origin proposed by the International League Against Epilepsy (ILAE) was possible in only 67.5% of patients. The most readily identifiable was motor cortex. In patients with unlocalized or generalized seizures the type of pathology was diffuse in 17% of patients and in 48.5% of patients, the lesion was located in the frontal brontoparietal lobe.


J Neurol Sci


Murthy JM,Yangala R




Has Abstract


1998-06-11 00:00:00














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    abstract:INTRODUCTION:Reports regarding outcome of Guillain-Barré syndrome (GBS) are usually limited to relatively short follow-up. We assessed the occurrence of fatigue and correlated it to clinical measures in patients who had suffered from GBS over 20 years previously. METHODS:We contacted 24 patients with GBS requiring in-...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Drory VE,Bronipolsky T,Bluvshtein V,Catz A,Korczyn AD

    更新日期:2012-05-15 00:00:00

  • Familial Creutzfeldt-Jakob disease.

    abstract::A Finnish family is described with 9 cases of presenile dementia in 3 generations. The mean age at onset was 52 years (range 46--62 years). Progressive dementia, upper motor neuron signs, muscular rigidity, and twitching, irregular tremors were consistent features in the 6 clinically investigated patients and were ass...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Haltia M,Kovanen J,Van Crevel H,Bots GT,Stefanko S

    更新日期:1979-08-01 00:00:00

  • The effects of bilateral subthalamic nucleus deep brain stimulation (STN DBS) on cognition in Parkinson disease.

    abstract::The effects of subthalamic nucleus (STN) stimulation on cognition and mood have not been well established. The authors estimated cognitive and mood effects of bilateral subthalamic nucleus deep brain stimulation (STN DBS) in patients with Parkinson's disease (PD) at 6 months and 1 year postoperatively. Forty-six patie...

    journal_title:Journal of the neurological sciences

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    更新日期:2008-10-15 00:00:00

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    journal_title:Journal of the neurological sciences

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Filippi M,Mastronardo G,Bastianello S,Rocca MA,Rovaris M,Gasperini C,Pozzilli C,Comi G

    更新日期:1998-07-15 00:00:00

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    journal_title:Journal of the neurological sciences

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    authors: Meyer HJ,Wienke A,Surov A

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  • The psychological impact of MND on patients and carers.

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    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Goldstein LH,Adamson M,Jeffrey L,Down K,Barby T,Wilson C,Leigh PN

    更新日期:1998-10-01 00:00:00

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    更新日期:2008-07-15 00:00:00

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    journal_title:Journal of the neurological sciences

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    authors: Eggers C,Hilker R,Burghaus L,Schumacher B,Heiss WD

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  • Improvement in motor evoked potentials and clinical course post-steroid therapy in multiple sclerosis.

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    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Salle JY,Hugon J,Tabaraud F,Boulesteix JM,Vallat JM,Dumas M,Poser CM

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    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,随机对照试验


    authors: Gasperini C,Hupperts R,Lycke J,Short C,McNeill M,Zhong J,Mehta LR

    更新日期:2016-11-15 00:00:00

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    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Nukada H

    更新日期:1993-11-01 00:00:00

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    abstract::The prevalence and pattern of cognitive impairment in systemic lupus erythematosus (SLE) patients with (NPSLE) and without (nSLE) overt neuropsychiatric manifestations were investigated. Fifty-two nSLE patients, 23 NPSLE patients and 27 healthy controls were evaluated with a battery of standardized neuropsychological ...

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    pub_type: 临床试验,杂志文章


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    更新日期:2001-02-15 00:00:00

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    journal_title:Journal of the neurological sciences

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    更新日期:2017-08-15 00:00:00

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    更新日期:2013-07-15 00:00:00

  • Gene expression changes in peripheral blood mononuclear cells from multiple sclerosis patients undergoing beta-interferon therapy.

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    authors: Singh MK,Scott TF,LaFramboise WA,Hu FZ,Post JC,Ehrlich GD

    更新日期:2007-07-15 00:00:00

  • An unusual case of a spasticity-lacking phenotype with a novel SACS mutation.

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    authors: Shimazaki H,Sakoe K,Niijima K,Nakano I,Takiyama Y

    更新日期:2007-04-15 00:00:00

  • Down-regulation of adenylate kinase 5 in temporal lobe epilepsy patients and rat model.

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    更新日期:2016-07-15 00:00:00

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    authors: Massacesi L,Vergelli M,Zehetbauer B,Liuzzi GM,Olivotto J,Ballerini C,Uccelli A,Mancardi L,Riccio P,Amaducci L

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    journal_title:Journal of the neurological sciences

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    authors: Zamarian L,Visani P,Delazer M,Seppi K,Mair KJ,Diem A,Poewe W,Benke T

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    authors: Low PA

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    journal_title:Journal of the neurological sciences

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    authors: Praamstra P,Stegeman DF,Kooijman S,Moleman J

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    pub_type: 杂志文章,评审


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    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Di Carlo A,Perna AM,Pantoni L,Basile AM,Bonacchi M,Pracucci G,Trefoloni G,Bracco L,Sangiovanni V,Piccini C,Palmarini MF,Carbonetto F,Biondi E,Sani G,Inzitari D

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    pub_type: 杂志文章


    authors: Sachdev PS,Chen X,Joscelyne A,Wen W,Altendorf A,Brodaty H

    更新日期:2007-09-15 00:00:00