Prenatal cocaine exposure: long-term deficits in learning and motor performance.

abstract：:Mass changes of skeletal muscles occur in a variety of species during the migratory period. Phenotypic flexibility of flight muscle mass is considered to represent adaptations of the flight muscle to changing power requirements associated with changes in body mass. We analyzed the relationship between muscle masses an...

journal_title：Annals of the New York Academy of Sciences

authors： Bauchinger U,Biebach H

更新日期：2005-06-01 00:00:00

abstract：:The paper describes an algorithm and computational system used to estimate the spatial chaos of magnetic resonance images of patients with gastric cancer and the quantum chaos of mechanoemission in blood. ...

journal_title：Annals of the New York Academy of Sciences

authors： Orel VE,Romanov AV,Dzyatkovskaya NN,Mel'Nik YI

更新日期：2002-10-01 00:00:00

abstract：:Organophosphorus pesticides (OPs) and nerve agents (NAs) are highly toxic chemicals that pose a significant threat to human health worldwide. These compounds induce status epilepticus (SE) by irreversibly blocking the ability of acetylcholinesterase to break down acetylcholine at neural synapses. Animal models of orga...

journal_title：Annals of the New York Academy of Sciences

authors： McCarren HS,McDonough JH Jr

更新日期：2016-06-01 00:00:00

abstract：:Aging is the outcome of the contest between chemistry and biology in living systems. Chronic, cumulative chemical modifications compromise the structure and function of biomolecules throughout the body. Proteins with long life spans serve as cumulators of exposure to chemical damage, which is detectable in the form of...

journal_title：Annals of the New York Academy of Sciences

authors： Baynes JW

更新日期：2002-04-01 00:00:00

abstract：:The damaging effects of superoxide in mitochondria leading to pathological disorders and aging are well documented and usually ascribed to superoxide's role as a precursor of reactive free radical species. However, the latest findings point out the importance of the nucleophilic properties of superoxide and its abilit...

journal_title：Annals of the New York Academy of Sciences

authors： Afanas'Ev IB

更新日期：2004-06-01 00:00:00

abstract：:As a result of intensive investigation, particularly in the pharmaceutical industry, a number of potent and selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonists have been discovered. The structure activity relationship studies that led to the discovery of these mGluR5 antagonists are presented in t...

journal_title：Annals of the New York Academy of Sciences

authors： Carroll FI

更新日期：2008-10-01 00:00:00

abstract：:Esophageal symptoms are common, and can arise from mucosal, motor, functional, and neoplastic processes, among others. Judicious use of diagnostic testing can help define the etiology of symptoms and can direct management. Endoscopy, esophageal high-resolution manometry (HRM), ambulatory pH or pH-impedance manometry, ...

journal_title：Annals of the New York Academy of Sciences

authors： Gyawali CP,de Bortoli N,Clarke J,Marinelli C,Tolone S,Roman S,Savarino E

更新日期：2018-12-01 00:00:00

abstract：:For various esophageal diseases, the search for alternative techniques for tissue repair has led to significant developments in basic and translational research in the field of tissue engineering. Applied to the esophagus, this concept is based on the in vitro combination of elements judged necessary for in vivo impla...

journal_title：Annals of the New York Academy of Sciences

authors： Arakelian L,Kanai N,Dua K,Durand M,Cattan P,Ohki T

更新日期：2018-12-01 00:00:00

abstract：:Research on nonhuman primates has produced compelling evidence for reconciliation and consolation, that is, postconflict contacts that serve to respectively repair social relationships and reassure distressed individuals, such as victims of attack. This has led to a view of conflict and conflict resolution as an integ...

journal_title：Annals of the New York Academy of Sciences

authors： de Wall FB,Aureli F

更新日期：1997-01-15 00:00:00

abstract：:About 1 of 10 women, particularly those older than 60 years of age, shows some degree of thyroid hormone deficiency. Thyroid diseases are generally characterized by perturbations of thyroid signaling homeostasis. The most common examples of thyroid diseases include hypothyroidism, hyperthyroidism, and several types of...

journal_title：Annals of the New York Academy of Sciences

authors： Pistollato F,Masias M,Agudo P,Giampieri F,Battino M

更新日期：2019-05-01 00:00:00

abstract：:Taking into account that methamphetamine (MA) is a popular recreational drug among young adult women, i.e., in gestational age, the present model aims to assess the effects of its exposure during development. In this experimental model, MA effects are assessed in the rat during the first month of life, regarding both ...

journal_title：Annals of the New York Academy of Sciences

authors： Gomes-DA-Silva J,Silva MC,Tavares MA

更新日期：1998-05-01 00:00:00

abstract：:Macrolide and polyether biosynthesis in actinomycetes is regulated at the level of precursor supply by effects of nutrients on the sources of the low-molecular-weight fatty acids used to build the carbon framework of these antibiotics. Ammonium ion appears to suppress the first enzymes of valine and threonine cataboli...

journal_title：Annals of the New York Academy of Sciences

authors： Tang L,Zhang YX,Hutchinson CR

更新日期：1994-05-02 00:00:00

abstract：:In keeping with the inflammatory paradigm of abdominal aortic aneurysm (AAA) pathophysiology, in vitro studies suggest that aneurysms secrete the proinflammatory cytokine interleukin-6 (IL-6). Circulating IL-6 levels are higher in patients with AAA with elevated circulating IL-6 an independent risk factor for cardiova...

journal_title：Annals of the New York Academy of Sciences

authors： Dawson J,Cockerill G,Choke E,Loftus I,Thompson MM

更新日期：2006-11-01 00:00:00

abstract：:Over most of the past century, it was thought that the adult brain was completely incapable of generating new neurons. However, in the last decade, the development of new techniques has resulted in an explosion of new research showing that (i) neurogenesis, the birth of new neurons, is not restricted to embryonic deve...

journal_title：Annals of the New York Academy of Sciences

authors： Arlotta P,Magavi SS,Macklis JD

更新日期：2003-06-01 00:00:00

abstract：:Acute viral infection of humans induces virus-specific serum antibody production that often persists for decades. To better understand the nature of this long-term antiviral antibody response, we studied antiviral antibody production of mice acutely infected with lymphocytic choriomeningitis virus (LCMV). Although thi...

journal_title：Annals of the New York Academy of Sciences

authors： Slifka MK,Ahmed R

更新日期：1996-10-25 00:00:00

abstract：:In electrical impedance cardiography, Kubicek's formula is often used to measure stroke volume from thoracic impedance variations synchronously to heart activity. To calculate stroke volume from impedance variations, the so-called outflow problem should be adequately solved. This outflow problem refers to the joint ca...

journal_title：Annals of the New York Academy of Sciences

authors： Faes TJ,Raaijmakers E,Meijer JH,Goovaerts HG,Heethaar RM

更新日期：1999-04-20 00:00:00

abstract：:Mice deficient for complement factors C3, C4, or C5 are resistant to experimental autoimmune myasthenia gravis (EAMG). Acetylcholine receptor (AChR) immune lymph node cells (LNC) of C3 deficient mice produce less interleukin 6 (IL-6), and EAMG-resistant IL-6 deficient mice have less serum C3. Increased serum C1q-circu...

journal_title：Annals of the New York Academy of Sciences

authors： Christadoss P,Tüzün E,Li J,Saini SS,Yang H

更新日期：2008-01-01 00:00:00

abstract：:The slowpoke gene of Drosophila melanogaster encodes a Ca-activated K channel. This gene is expressed in neurons, muscles, tracheal cells, and the copper and iron cells of the midgut. The gene produces a large number of alternative products using tissue-specific transcriptional promoters and alternative mRNA splicing....

journal_title：Annals of the New York Academy of Sciences

authors： Atkinson NS,Brenner R,Bohm RA,Yu JY,Wilbur JL

更新日期：1998-11-16 00:00:00

abstract：:Though several studies show that genetic factors influence individual differences in musical engagement, aptitude, and achievement, no study to date has investigated whether specialization among musically active individuals in terms of choice of instrument and genre is heritable. Using a large twin cohort, we explored...

journal_title：Annals of the New York Academy of Sciences

authors： Mosing MA,Ullén F

更新日期：2018-05-09 00:00:00

abstract：:Aging, hypoxia, and thiamin deficiency diminish motor performance. Similar alterations of ACh, DA, and glutamate metabolism accompany hypoxia, thiamin deficiency, and aging. Both aging and hypoxia reduce ACh release and stimulate DA and glutamate release. Presynaptic enhancement of DA and glutamate release may be impo...

journal_title：Annals of the New York Academy of Sciences

authors： Freeman GB,Gibson GE

更新日期：1988-01-01 00:00:00

abstract：:In red blood cells as well as in platelets there appears to be a decrease in adenine nucleotides during storage under blood bank conditions. This can be decreased by use of anticoagulant preservatives with higher phosphate content than the standard ACD solution, through the addition of adenine and inosine. Maintenance...

journal_title：Annals of the New York Academy of Sciences

authors： Ambrus JL,Ambrus CM,Odake K,Mink IB,Shields R,Warner W,Bishop C,Tritsch GL,Golden G,Mittelman A

更新日期：1975-08-08 00:00:00

abstract：:Methamphetamine (METH), a highly addictive drug, can cause degeneration of monoaminergic terminals and neuronal apoptosis in the mammalian brain. In the present article, we have used serial analysis of gene expression (SAGE) to investigate patterns of gene expression in the striata of rats that were given a neurotoxic...

journal_title：Annals of the New York Academy of Sciences

authors： Cai NS,McCoy MT,Ladenheim B,Lyles J,Ali SF,Cadet JL

更新日期：2006-08-01 00:00:00

abstract：:Bone marrow cells of various animal species and the human produce a group of bioregulatory peptides called myelopeptides (MPs). A highly purified myelopeptide (MP) fraction and some individual molecules have been isolated from the supernatant of the porcine bone marrow cell culture by successive gel chromatography and...

journal_title：Annals of the New York Academy of Sciences

authors： Petrov RV

更新日期：1993-06-23 00:00:00

abstract：:Vitamins C and E function as water-soluble and lipid-soluble chain-breaking antioxidants, respectively, and protect lipids, proteins, and membranes from oxidative damage. Vitamin C scavenges oxygen radicals in the aqueous phase, whereas vitamin E scavenges oxygen radicals within the membranes. Vitamin C regenerates vi...

journal_title：Annals of the New York Academy of Sciences

authors： Niki E

更新日期：1987-01-01 00:00:00

abstract：:Child maltreatment (CM) not only has detrimental and lifelong psychological consequences, but also can lead to lasting alterations in core physiological systems--a biological memory of CM. Furthermore, some of these alterations might even be transmitted to the next generation. This article describes current knowledge ...

journal_title：Annals of the New York Academy of Sciences

authors： Schury K,Kolassa IT

更新日期：2012-07-01 00:00:00

abstract：:Recent years have witnessed an explosive growth in available biological data. This includes a tremendous quantity of sequence data (e.g., biological structures, genetic and physical maps, pathways) generated by genome and transcriptome projects focused on humans, mice, and a multitude of other species. Diabetes resear...

journal_title：Annals of the New York Academy of Sciences

authors： Petrovsky N,Silva D

更新日期：2004-12-01 00:00:00

abstract：:New aggressive pathogens are responsible for the increasing incidence and difficult management of infections. Modern epidemics such as diabetes are frequently complicated by severe infections with subsequent high morbidity. Diagnosis (essentially early detection of infection) and also management decision making pose c...

journal_title：Annals of the New York Academy of Sciences

authors： Israel O,Keidar Z

更新日期：2011-06-01 00:00:00

abstract：:The natural tetrapeptide acetyl-ser-asp-lys-pro (AcSDKP) is formed in vivo by enzymatic cleavage of the N terminus of thymosin beta4 by prolyl oligopeptidase (POP). Recently, AcSDKP was shown to promote angiogenesis. Because of the critical role of neovascularization in cancer development, the levels of AcSDKP and POP...

journal_title：Annals of the New York Academy of Sciences

authors： Liu JM,Garcia-Alvarez MC,Bignon J,Kusinski M,Kuzdak K,Riches A,Wdzieczak-Bakala J

更新日期：2010-04-01 00:00:00

abstract：:Recent studies have reported an association between exposure to childhood abuse or neglect and alterations in brain structure or function. One limitation of these studies is that they are correlational and do not provide evidence of a cause-effect relationship. Preclinical studies on the effects of exposure to early l...

journal_title：Annals of the New York Academy of Sciences

authors： Teicher MH,Tomoda A,Andersen SL

更新日期：2006-07-01 00:00:00

abstract：:Hepatitis B virus (HBV) of man has several characteristics that distinguish it from viruses of other groups. These include its ultrastructure, viral DNA size and structure, a virion DNA polymerase which repairs a single-stranded region in the viral DNA, liver tropism, character of persistent infection, and association...

journal_title：Annals of the New York Academy of Sciences

authors： Robinson WS

更新日期：1980-01-01 00:00:00