Microperoxidase-11: molecular dynamics and Q-band excited resonance Raman of the oxidized, reduced and carbonyl forms.

Abstract:

:Resonance Raman spectra with Q-band excitation are reported for microperoxidase-11, the cytochrome c analog. Spectra were acquired in the mid-frequency range for the oxidized, and reduced forms of the undecapeptide, as well as for the imidazole and carbonyl complexes. Oxidation and spin state marker bands of the undecapeptides are consistent with a six-coordinate, low spin iron in both oxidation states. Porphyrin core size correlations yield a porphyrin-centre to pyrrole-nitrogen distance of 2.00 A for MP11, suggestive of a six-coordinate species in a distorted heme environment. Molecular dynamics results show that the non-planarity of the heme of the parent cytochrome is conserved in the microperoxidase and its carbonmonoxy analog.

journal_name

J Biomol Struct Dyn

authors

Laberge M,Vreugdenhil AJ,Vanderkooi JM,Butler IS

doi

10.1080/07391102.1998.10508999

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

1039-50

issue

6

eissn

0739-1102

issn

1538-0254

journal_volume

15

pub_type

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