Plasma L-arginine concentration, oxygenation index, and systemic blood pressure in premature infants.

abstract：OBJECTIVE:To investigate whether inhibition of cyclooxygenase-2, a critical component of the inflammatory pathway, is neuroprotective in a neonatal rat model of cerebral hypoxia-ischemia. The development of brain inflammation largely contributes to neonatal brain injury that may lead to a lifetime of neurologic deficit...

journal_title：Critical care medicine

authors： Fathali N,Ostrowski RP,Lekic T,Jadhav V,Tong W,Tang J,Zhang JH

更新日期：2010-02-01 00:00:00

abstract：:Clonidine may be a source of serious toxicity when ingested by toddlers. We describe 11 cases of clonidine ingestion by toddlers (mean dose 0.15 mg/kg; range 0.01 to 0.57). The source of the clonidine was a grand-parent in six of 11 cases. Symptoms included altered level of consciousness (n = 11), miosis (n = 5), brad...

journal_title：Critical care medicine

authors： Fiser DH,Moss MM,Walker W

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:Acute lung injury secondary to smoke inhalation is a major source of morbidity and mortality in burn patients. We tested the hypothesis that nebulized epinephrine would ameliorate pulmonary dysfunction secondary to acute lung injury by reducing airway hyperemia and edema formation and mediating bronchodilatat...

journal_title：Critical care medicine

authors： Lange M,Hamahata A,Traber DL,Cox RA,Kulp GA,Nakano Y,Traber LD,Herndon DN,Enkhbaatar P

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To study the effect of early and continuous venovenous hemofiltration (CVVH) on the plasma concentrations of several humoral mediators of inflammation and subsequent organ dysfunction in septic patients. DESIGN:Randomized, controlled trial. SETTING:Intensive care unit of a tertiary hospital. PATIENTS:Twent...

journal_title：Critical care medicine

authors： Cole L,Bellomo R,Hart G,Journois D,Davenport P,Tipping P,Ronco C

更新日期：2002-01-01 00:00:00

abstract：:Fifteen patients with septic shock and perfusion failure received a 20-min infusion of glucose-insulin-potassium (GIK, glucose 50%, 1 g/kg body weight; insulin 1.5 U/kg, potassium, 10 mMol) after volume loading and vasoactive medication had failed to eliminate hypotension and lactacidemia. Hemodynamic and oxygen measu...

journal_title：Critical care medicine

authors： Bronsveld W,van den Bos GC,Thijs LG

更新日期：1985-07-01 00:00:00

abstract：:Simple insertion of a nasogastric (NG) tube was successful in only 52 of 100 anesthetized intubated patients. After the larynx was manually pulled forward, the NG tube was successfully inserted in 33 patients. In the remaining 15 patients, the NG tube was inserted only with the aid of a finger or a laryngoscope used w...

journal_title：Critical care medicine

authors： Perel A,Ya'ari Y,Pizov R

更新日期：1985-03-01 00:00:00

abstract：:Transcutaneous PO2 (PtcO2), PaO2, PtcO2 arterial index (ARI; PtcO2/PaO2), and the initial slope index (ISI; [delta PO2/min]/starting PtcO2) were measured in 42 healthy volunteers, 12 patients with stable circulation and respiratory insufficiency, and ten patients with insufficient peripheral circulation in cardiogenic...

journal_title：Critical care medicine

authors： Lemke R,Klaus D,Lübbers DW,Oevermann G

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVE:To compare the ability of two methods--Acute Physiology and Chronic Health Evaluation (APACHE II) and Mortality Prediction Model (MPM)--to predict hospital outcome for a large group of intensive care patients from Britain and Ireland. DESIGN:Prospective, multicenter, cohort study. SETTING:Twenty-six general...

journal_title：Critical care medicine

authors： Rowan KM,Kerr JH,Major E,McPherson K,Short A,Vessey MP

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:We sought to review findings from recent literature on the postresuscitation care of cardiac arrest patients using therapeutic hypothermia as part of nontrial treatment. DESIGN:Literature review. SETTING:Hospital-based environment. SUBJECTS:Patients initially resuscitated from cardiac arrest who underwent...

journal_title：Critical care medicine

authors： Sagalyn E,Band RA,Gaieski DF,Abella BS

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:After a stay in the intensive care unit, patients risk experiencing delusional memories, memory loss, and symptoms of posttraumatic stress. Since the 1990s, diaries have been kept for intensive care unit patients to help fill in memory gaps, aid psychosocial recovery, and improve health-related quality of lif...

journal_title：Critical care medicine

authors： Egerod I,Christensen D,Schwartz-Nielsen KH,Agård AS

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To investigate the interaction and involvement of hydrogen sulfide and transient receptor potential vanilloid type 1 in the pathogenesis of sepsis. Hydrogen sulfide has been demonstrated to be involved in many inflammatory states including sepsis. Its contribution in neurogenic inflammation has been suggested...

journal_title：Critical care medicine

authors： Ang SF,Moochhala SM,Bhatia M

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To determine the impact of the rotation of antimicrobial agents on the rates of infection, intestinal colonization, and acquisition with antimicrobial-resistant Gram-negative bacteria. DESIGN:Pre- and postintervention design. SETTING:A 19-bed, medical intensive care unit. PATIENTS:Individuals admitted to t...

journal_title：Critical care medicine

authors： Warren DK,Hill HA,Merz LR,Kollef MH,Hayden MK,Fraser VJ,Fridkin SK

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Acute respiratory distress syndrome is an abrupt inflammatory illness that involves damage from reactive oxygen species. We examined the efficacy and safety of oxothiazolidine-4-carboxylic acid (OTZ), a free radical scavenger, in treating acute respiratory distress syndrome. DESIGN:Double-blind, placebo-cont...

journal_title：Critical care medicine

authors： Morris PE,Papadakos P,Russell JA,Wunderink R,Schuster DP,Truwit JD,Vincent JL,Bernard GR

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:In postcardiac surgery patients, we often noticed that monitored tidal volumes exceeded the ventilator settings. We investigated whether cardiogenic oscillation causes overestimation of tidal volume. DESIGN:Prospective, observational, clinical study. SETTING:Surgical intensive care unit in a national heart...

journal_title：Critical care medicine

authors： Imanaka H,Takeuchi M,Tachibana K,Nishimura M

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVES:Acute renal failure is a complication in critically ill patients that has been associated with an excess risk of hospital mortality. Whether this reflects the severity of the disease or whether acute renal failure is an independent risk factor is unknown. The aim of this study was to analyze severity of illn...

journal_title：Critical care medicine

authors： Metnitz PG,Krenn CG,Steltzer H,Lang T,Ploder J,Lenz K,Le Gall JR,Druml W

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:Most knowledge related to the pathophysiology of microcirculation in ischemic stroke comes from experimental research. Unfortunately, data on microcirculation in the human brain are limited, partially as a result of the lack of appropriate investigational techniques. The objective of our study was to test th...

journal_title：Critical care medicine

authors： Pérez-Bárcena J,Goedhart P,Ibáñez J,Brell M,García R,Llinás P,Jiménez C,Ince C

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:To determine the incidence and characteristics of children with brain death in the pediatric intensive care unit (ICU), and to assess the incidence of the clinical triad (Turner's triad) of central diabetes insipidus, low glucose demand, and low CO2 production. DESIGN:Retrospective review of medical records...

journal_title：Critical care medicine

authors： Staworn D,Lewison L,Marks J,Turner G,Levin D

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:To compare the impact of two different customization strategies in the performance of the admission Mortality Probability Model II (MPM II0) using formal statistical assessment. DESIGN:Analysis of the database of a multicenter, multinational, prospective cohort study, EURICUS-1, involving 89 intensive care u...

journal_title：Critical care medicine

authors： Moreno R,Apolone G

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To describe a case of intentional ingestion of hand sanitizer in our hospital and to review published cases and those reported to the American Association of Poison Control Centers' National Poison Data System. DESIGN:A case report, a literature review of published cases, and a query of the National Poison D...

journal_title：Critical care medicine

authors： Gormley NJ,Bronstein AC,Rasimas JJ,Pao M,Wratney AT,Sun J,Austin HA,Suffredini AF

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Secretoneurin is associated with cardiomyocyte Ca handling and improves risk prediction in patients with acute myocardial dysfunction. Whether secretoneurin improves risk assessment on top of established cardiac biomarkers and European System for Cardiac Operative Risk Evaluation II in patients undergoing ca...

journal_title：Critical care medicine

authors： Brynildsen J,Petäjä L,Myhre PL,Lyngbakken MN,Nygård S,Stridsberg M,Christensen G,Ottesen AH,Pettilä V,Omland T,Røsjø H

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:Several studies have suggested that intravenous hydroxyethyl starch treatment may dampen acute inflammatory responses. It is well documented that limited oxygen delivery to tissues (hypoxia) is common in acute inflammation, and numerous parallels exist between acute responses to hypoxia and to inflammation, i...

journal_title：Critical care medicine

authors： Dieterich HJ,Weissmüller T,Rosenberger P,Eltzschig HK

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:Carbon monoxide poisoning affects 50,000 per year in the United States alone. Mortality is approximately 3%, and up to 40% of survivors suffer from permanent neurocognitive and affective deficits. Hyperbaric oxygen therapy has shown benefit on reducing the long-term neurologic sequelae of carbon monoxide poi...

journal_title：Critical care medicine

authors： Rose JJ,Nouraie M,Gauthier MC,Pizon AF,Saul MI,Donahoe MP,Gladwin MT

更新日期：2018-07-01 00:00:00

abstract：:Two new catecholamines, dopamine and dobutamine, have found widespread use for cardiovascular support. The relative efficacy of these drugs in aiding resuscitation from cardiopulmonary arrest is unknown. Dogs were subjected to either asphyxial or fibrillatory cardiac arrest. Resuscitation was attempted with artificial...

journal_title：Critical care medicine

authors： Otto CW,Yakaitis RW,Redding JS,Blitt CD

更新日期：1981-09-01 00:00:00

abstract：:We evaluated 95 extubated neonates to determine if certain risk factors could predict the development of laryngeal injury. Risk factors were recorded prospectively during the intubation period and correlated with laryngeal injury determined by laryngoscopy after extubation. Duration of intubation greater than or equal...

journal_title：Critical care medicine

authors： Fan LL,Flynn JW,Pathak DR

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVES:Optimistic expectations about prognosis by surrogate decision-makers in ICUs are common, but there are few data about the causes and clinical consequences. Our objective was to determine the causes of optimistic expectations about prognosis among surrogates and whether it is associated with more use of life ...

journal_title：Critical care medicine

authors： White DB,Carson S,Anderson W,Steingrub J,Bird G,Curtis JR,Matthay M,Peterson M,Buddadhumaruk P,Shields AM,Ernecoff N,Shotsberger K,Weissfeld L,Chang CH,Pike F,Lo B,Hough CL

更新日期：2019-09-01 00:00:00

abstract：:Although systolic dysfunction of the left ventricle has been characterized in septic shock (SS) and sepsis without shock (SWS), diastolic abnormalities are less well characterized. Diastolic filling was determined using pulsed Doppler transmitral spectral tracings in 13 patients with SS, ten patients with SWS, and 33 ...

journal_title：Critical care medicine

authors： Jafri SM,Lavine S,Field BE,Bahorozian MT,Carlson RW

更新日期：1990-07-01 00:00:00

abstract：:High-risk patients who survived general (noncardiac) surgery were observed to have cardiac index (CI) values averaging 4.5 L/min.m2, oxygen delivery (DO2) greater than 600 ml/min.m2, and oxygen consumption (VO2) 170 ml/min.m2 during the first 2 or three days postoperatively. Patients who subsequently died maintained r...

journal_title：Critical care medicine

authors： Shoemaker WC,Kram HB,Appel PL

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the prognostic value of sublingual PCO2 (P(SL)CO2), lactate concentration, and mixed venous oxygen saturation (S(MV)O2) in hemodynamically unstable intensive care patients and, additionally, to compare the temporal changes of these variables in response to treatment....

journal_title：Critical care medicine

authors： Marik PE,Bankov A

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To compare measurement of cardiac output by the CO2 rebreathing method vs. the thermodilution cardiac output technique in the setting of acute respiratory failure in patients with chronic obstructive pulmonary disease. DESIGN:Prospective, comparative study of two methods in a consecutive sample. SETTING:Int...

journal_title：Critical care medicine

authors： Neviere R,Mathieu D,Riou Y,Guimez P,Renaud N,Chagnon JL,Wattel F

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:The elevation of the percentage of regulatory CD4+CD25+ T lymphocytes (Treg) has been recently described during septic shock. The objective of the present study was to investigate whether this increased percentage was due to Treg proliferation. DESIGN:Observational study. SETTING:Adult intensive care units ...

journal_title：Critical care medicine

authors： Venet F,Pachot A,Debard AL,Bohé J,Bienvenu J,Lepape A,Monneret G

更新日期：2004-11-01 00:00:00