Abstract:
:The cost and efficiency of training clinical centre staff and of duplicate data entry in clinical trials is reviewed. Training is an essential component of quality assurance programmes and it is usually carried out at regular intervals in long-term clinical trials. Initial training of staff and regular retraining is important to assure standardization and it can lead to reduced trial costs. Interim training for new staff and for remedial purposes is less efficient than regularly scheduled training sessions. Regional centres for training and the use of computer aided instruction are two ways such interim training can be made more efficient and standardized. Duplicate data entry or verification can result in a substantial reduction in data entry errors depending on the nature of the data being keyed. Selective verification should especially be considered for important fields for which consistency checks cannot be performed, that are alphabetic or that are several characters in length. Quality assurance procedures should be implemented to monitor data entry accuracy in clinical trials.
journal_name
Stat Medjournal_title
Statistics in medicineauthors
Neaton JD,Duchene AG,Svendsen KH,Wentworth Ddoi
10.1002/sim.4780090118subject
Has Abstractpub_date
1990-01-01 00:00:00pages
115-23; discussion 124issue
1-2eissn
0277-6715issn
1097-0258journal_volume
9pub_type
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