G alpha q cDNA sequence from human platelets.

Abstract:

:G-proteins play a major role in cell signaling and specific abnormalities in these proteins have been implicated in some diseases. Although, two human G alpha q coding sequences are published, they differ at functionally important regions. We have sequenced the human G alpha q cDNA synthesized from normal platelet mRNA by reverse transcription. Our results showed that the penultimate amino acid leucine is conserved in the human G alpha q sequence which has 94.4% identity in nucleotide sequence and 99.2% homology in amino acid sequence with murine sequence.

journal_name

Thromb Res

journal_title

Thrombosis research

authors

Gabbeta J,Dhanasekaran N,Rao AK

doi

10.1016/s0049-3848(98)00071-1

subject

Has Abstract

pub_date

1998-07-01 00:00:00

pages

29-32

issue

1

eissn

0049-3848

issn

1879-2472

pii

S0049-3848(98)00071-1

journal_volume

91

pub_type

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