Abstract：
:Although current methodology for human health risk assessment assumes additive interactions among the contaminants of a complex mixture, chemical interactions may occur which produce synergistic or antagonistic effects. In this study, the mutagenic response of three f2p4l compounds, benzo(a)pyrene (B(a)P), pentachlorophenol (PCP) and 2,4,6-trinitrotoluene (TNT), were tested individually and in binary and tertiary solutions, using the Salmonella/microsome assay with each of three bacterial tester strains (TA97a, TA98, and TA100). For all strains, B(a)P was mutagenic with metabolic activation (Arochlor 1254-induced Sprague-Dawley rat liver S9 fraction), TNT was mutagenic without metabolic activation, and pentachlorophenol was inactive both with and without metabolic activation. In binary and tertiary solutions, pentachlorophenol had no effect on the mutagenicity of B(a)P or TNT, independent of metabolic activation. For strain TA97a, the mutagenicity of B(a)P with metabolic activation was slightly decreased in the presence of TNT; the mutagenicity of TNT without metabolic activation was slightly decreased in the presence of B(a)P and PCP; and the mutagenicity of the tertiary solution (496 revertants/10 ug) with metabolic activation was lower than the mutagenicity of B(a)P alone (729 revertants/10 ug). The mutagenicity of B(a)P in strain TA98 with activation was inhibited by the addition of TNT. Studies conducted using several concentrations of TNT or B(a)P indicate that the inhibition of B(a)P mutagenicity was increased as the concentration of TNT increased. Assays performed using four concentrations of S9 indicated the inhibition of B(a)P mutagenicity was relatively unaffected by the level of S9. The data suggest that an interaction in the presence of TNT limits the concentration of B(a)P that is capable of reaching or binding with bacterial DNA.
journal_name
Chemospherejournal_title
Chemosphereauthors
Donnelly KC,Claxton LD,Huebner HJ,Capizzi JLdoi
10.1016/s0045-6535(98)00123-4subject
Has Abstractpub_date
1998-09-01 00:00:00pages
1253-61issue
7eissn
0045-6535issn
1879-1298pii
S0045653598001234journal_volume
37pub_type
杂志文章相关文献
CHEMOSPHERE文献大全abstract：:To investigate the environmental levels and profiles of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), polybrominated diphenyl ethers (PBDEs), and polychlorinated biphenyls (PCBs), tree bark samples (n=22) were collected from Luqiao, an E-waste recycling area, in east China in July 11-13, 2006. The ave...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2008.10.002
更新日期：2009-02-01 00:00:00
abstract：:Fomesafen is widely used in agriculture and can be detected in the environment and agricultural products. Research on the developmental toxicity of fomesafen in animals is currently very limited. Here, we used zebrafish as an animal model to evaluate the toxicity of fomesafen in developing aquatic vertebrates and high...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127380
更新日期：2020-11-01 00:00:00
abstract：:Reducing bioassay variability by identifying sources of variation and controlling important parameters in assay protocol was demonstrated in this study. The variability of a bioassay based on a luminescent bacterium was examined as an example. This assay involved the growth of cells, storage at a low temperature, acti...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2004.07.001
更新日期：2004-10-01 00:00:00
abstract：:In this study, the degradation kinetics of iopamidol (IPM) by three different UV-based oxidation processes including UV/hydrogen peroxide (H2O2), UV/persulfate (PDS) and UV/chlorine (NaClO) were examined and the potential formation of iodinated disinfection byproducts (I-DBPs) in these processes followed by sequential...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.12.162
更新日期：2019-04-01 00:00:00
abstract：:Remediation of polluted groundwater often requires oxygen delivery into subsurface to sustain aerobic bacteria. Air sparging or injection of oxygen containing solutions (e.g., hydrogen peroxide) into the subsurface are common. In this study visible light was delivered into the subsurface using radially emitting optica...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.12.089
更新日期：2018-03-01 00:00:00
abstract：:Platinum group elements (PGEs), platinum, palladium and rhodium are widely used in automobile catalytic converters. PGEs are emitted into the environment and enter the aquatic ecosystem via runoff rainwater. The present study investigated the bioavailability of platinum chloride for the zebrafish (Danio rerio) and the...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2009.08.033
更新日期：2009-11-01 00:00:00
abstract：:A number of pharmaceutically active compounds (PhACs) have been detected in the aquatic environment as a result of discharges of municipal wastewater. In the state of Louisiana, USA, many municipalities treat wastewater using natural systems, such as lagoons and wetlands, rather than conventional wastewater treatment ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2008.09.020
更新日期：2008-12-01 00:00:00
abstract：:Dissolved organic nitrogen (DON) can act as precursor of nitrogenous disinfection by-products formed during chlorination disinfection. The performances of biological fluidized bed (continuous stirred tank reactor, CSTR) and bio-ceramic filters (plug flow reactor, PFR) were compared in this study to investigate the inf...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2014.12.059
更新日期：2015-11-01 00:00:00
abstract：:Sediments were collected from areas that were going to be dredged located at six small Greek ports, as well as from possible disposal areas. In order to assess the contamination level of dredged material, the samples were analysed for pH, organic matter, the metals Cd, Pb, Hg, Cr, Ni, Cu, Zn and major organic compound...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2008.02.049
更新日期：2008-06-01 00:00:00
abstract：:Although the use of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) has been prohibited in Singapore since 1980, OCPs and PCBs still can be detected in the environment and represent a potential threat to public health. In this study, OCPs and PCBs were measured in house dust samples collected fro...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2007.03.051
更新日期：2007-08-01 00:00:00
abstract：:Lead (Pb2+) is a major public health hazard for urban children, with profound and well-characterized developmental and behavioral implications across the lifespan. The ability of early Pb2+ exposure to induce epigenetic changes is well-established, suggesting that Pb2+-induced neurobehavioral deficits may be heritable...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.125527
更新日期：2020-04-01 00:00:00
abstract：:Mixing pesticides with different modes of action can provide a wider spectrum of control with fewer applications compared to using single active ingredients and is essential for comprehensive management of pest resistance. Mixture studies with pesticides are performed to assess compatibility, combined efficacy, and po...
journal_title：Chemosphere
pub_type： 杂志文章,评审
doi：10.1016/j.chemosphere.2018.06.081
更新日期：2018-10-01 00:00:00
abstract：:The role of chemical components of cork in the sorption of several pesticides has been investigated. For this purpose raw cork and three cork extracted fractions (i.e. cork free of aliphatic extractives, cork free of all extractives and cork free of all extractives and suberin) were used as sorbent of three ionic pest...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2014.08.051
更新日期：2015-01-01 00:00:00
abstract：:Sediment characteristics are well known to interfere with toxicity, mainly through differences in terms of bioaccumulation. Here, with chironomids exposed to zinc in an artificial and a field sediment, we investigated the differences of zinc accumulation and of effects on the life cycle, at individual and population l...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2006.06.040
更新日期：2007-01-01 00:00:00
abstract：:Plastics debris, especially microplastics, have been found worldwide in all marine compartments. Much research has been carried out on adsorbed pollutants on plastic pieces and hydrophobic organic compounds (HOC) associated with microplastics. However, only a few studies have focused on plastic additives. These chemic...
journal_title：Chemosphere
pub_type： 杂志文章,评审
doi：10.1016/j.chemosphere.2017.05.096
更新日期：2017-09-01 00:00:00
abstract：:Wetland microcosms were used to evaluate the ability of constructed wetlands to remove extremely high concentrations of selenocyanate (SeCN-), arsenic (As), and boron (B) from wastewater generated by a coal gasification plant in Indiana. The wetland microcosms significantly reduced the concentrations of selenium (Se),...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/S0045-6535(03)00497-1
更新日期：2003-09-01 00:00:00
abstract：:Tolerance of wood decay fungi of the genera Agrocybe, Armillaria, Auricularia, Daedalea, Pleurotus, Trametes to the presence of various amounts of creosote-treated wood (CTW) in the growth medium was compared. In the case of the most tolerant strain, Pleurotus ostreatus SMR 684, extracellular laccase and peroxidase sp...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2008.04.014
更新日期：2008-07-01 00:00:00
abstract：:Populations subject to anthropogenic contaminants often display altered patterns of genetic variation, including decreased genetic variability. Selective pressures of contaminant exposure are also reflected in differential tolerance between genotypes. An industrial chemical spill in a major eastern Australian waterway...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2013.05.079
更新日期：2013-10-01 00:00:00
abstract：:The single and multi-stages advanced oxidation process (AOP)-biological treatments were evaluated to apply for drinking water treatment, especially for the water containing less susceptible dissolved organic carbon (DOC) to ozone, comparing with the ozonation-biological treatment. Minaga reservoir water and the second...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(02)00617-3
更新日期：2003-03-01 00:00:00
abstract：:The migration of uranium(VI) in subsurface environments is strongly influenced by its adsorption/desorption reactions at the solid/solution interface. Phosphate is often present in subsurface systems and was shown to significantly affect U(VI) adsorption in previous batch experiments. In this study, column experiments...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2007.01.063
更新日期：2007-07-01 00:00:00
abstract：:Honey bees provision glandular secretions in the form of royal jelly as larval nourishment to developing queens. Exposure to chemicals and nutritional conditions can influence queen development and thus impact colony fitness. Previous research reports that royal jelly remains pesticide-free during colony-level exposur...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.128183
更新日期：2021-01-01 00:00:00
abstract：:The photocatalytic oxidation of the organic pollutants with the TiO2 as photocatalyst has been widely studied in the world, and many achievements have been got. The degradation of pollutants is highly related with the photocatalytic activity of TiO2. It is demonstrated that doping ions or oxides to TiO2 is one way to ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2004.01.035
更新日期：2004-06-01 00:00:00
abstract：:In this study, investigation were done on the Mahanadi River water and health of dwelling Indian Knife fish Notopterus notopterus from three sites along the course of the river in an around Cuttack city (Odisha). Oxidative stress biomarker assays such as thiobarbituric acid reactive substances, protein carbonyls, prot...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.04.035
更新日期：2016-07-01 00:00:00
abstract：:The bioremediation efficiency of petroleum hydrocarbons in natural soil-water systems is regulated by active microbial populations and other system parameters. Relevant factors include the transfer rate of petroleum contaminants from a medium into microorganisms, the partitioning behavior of contaminants from water in...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.05.202
更新日期：2019-10-01 00:00:00
abstract：:The effect of flutriafol on the cellulose decomposition was studied in the laboratory as a dose-response experiment using a trade marked formulation. Cellulose degradation rates were determined by the weight loss from cellulose filter disks buried in soil samples and by the CO2 evolved during batch incubation experime...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(99)00512-3
更新日期：2000-10-01 00:00:00
abstract：:The present investigation determined the effects of epibrassinolide (EBL) on the levels of indole-3-acetic acid (IAA), abscisic acid (ABA), and polyamine (PA) and antioxidant potential of 7-d old Raphanus sativus L. cv. 'Pusa chetki' seedlings grown under Cr (VI) metal stress. Reduced titers of free (0.767 μg g(-1) FW...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.03.056
更新日期：2011-07-01 00:00:00
abstract：:Bentonite was modified by introducing humic acid (HA) into interlayer space of bentonite. The structural and physicochemical properties of modified bentonite were determined by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), X-ray powder diffraction (XRD) and thermogravimetric anal...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.126976
更新日期：2020-09-01 00:00:00
abstract：:Dissipation of alachlor in soil and plant in field condition (cotton cropping system), and in soil, water and fish in simulated model ecosystem was investigated. The acetanilide herbicide, alachlor (50% w/w EC) was applied as pre-emergence at 2.5 and 5.0 kg a.i.ha(-1) three days after sowing the cotton seeds in the fi...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2003.08.008
更新日期：2004-02-01 00:00:00
abstract：:The anaerobic stabilization of raw sludges of different origin was investigated. Precursors like chlorophenol and chlorobenzene isomers were added to some of the samples. The change of the PCDD/F concentrations as well as the change in the pattern of the isomers and congeners was independent of the type and amount of ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/0045-6535(95)00210-y
更新日期：1995-10-01 00:00:00
abstract：:The oribatid mite, Oppia nitens, has gained recognition in recent laboratory ecotoxicological tests, however, the species global distribution is limited to temperate regions and not ecologically relevant for tropical soils. The present study reports the first laboratory study aimed at assessing the ecotoxicity of cont...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.11.173
更新日期：2019-03-01 00:00:00
