A proactive, data-based determination of the standard of medical care in pediatrics.

Abstract:

:A 3-week-old infant awoke with a fever. He was taken to the doctor who noted that the child was irritable. The doctor took him to the hospital where a resident performed a spinal tap, started an intravenous (IV) line, and ordered antibiotics. The entire drama, from entering the doctor's office to infusion of ampicillin, took 2 hours. The doctor was sued for malpractice. Expert witnesses for the plaintiff testified that he had deviated from the standard of medical care by taking too long to administer antibiotics, which, in their view, ought to have been given within 30 minutes. Expert witnesses for the defense testified that 2 hours to administer antibiotics in this case was within the standard of care. What ought to be the response of the pediatric community to discrepant expert testimony such as this? One possible response is nothing. Lawyers from both sides will find expert medical witnesses who articulate positions favorable to their clients (as they did in this case), and the truth will emerge after vigorous cross-examination. This, we suggest, is inadequate. We believe that some expert opinions can be viewed as better than others. That is, some opinions describe the standard of medical care correctly while other expert opinions are (to put it charitably) idiosyncratic, failing to depict accurately the skill and care ordinarily administered in comparable situations. Currently, jurors are informed about the standard of care by expert witnesses, who rely on their own medical knowledge and experience. However, a huge body of literature demonstrates that recollections of individual experience are inevitably flawed, and flawed in a nonrandom direction (the Monday morning quarterback phenomenon). Consider the infant with meningitis. When experts in pediatric emergency medicine and pediatric infectious diseases (ID) were asked about the median time from emergency room (ER) presentation to administration of antibiotics in a child with suspected meningitis, their opinions were wrong and slanted toward the outcome known to be desired (namely, a shorter elapsed time). ER physicians (median estimated time to antibiotic administration [AB-TIME] = 46 minutes) and ID physicians (median estimated AB-TIME = 80 minutes) consistently underestimated the actual median value of AB-TIME determined by chart review (120 minutes). From the judicial perspective such potential flaws in expert testimony are assumed to be equally distributed among experts. All admissible evidence is a priori of equal weight until a jury decides otherwise. The standard of medical care is created anew by expert testimony in each individual case, disappearing, like Brigadoon, upon resolution of the dispute. However, to anyone but a lawyer, the standard of medical care must exist as something outside the courtroom testimony of experts, and if it does exist, it should be easily described so that expert testimony can be judged more (or less) accurate in depicting it. We contend that medical care is not a single behavior that conforms to or deviates from an idiosyncratic and retrospectively determined standard, but rather a distribution of behaviors in response to a variety of medical circumstances. For a given scenario, each of several possible responses can be ascribed a relative frequency based on empirical data, and the consequent normal curve depicts the totality of medical care. Substandard care then falls out neatly as behaviors lying outside the large majority of cases. Juries would be empowered (as they are currently) to determine exactly where on this curve substandard care lies, but at least the debate would share the same description of reality. Recent US Supreme Court guidelines regarding expert testimony provide an opportunity to expand the use of databases in medical negligence cases. The Court restricted expert testimony to "scientific knowledge ... based on generating hypotheses and testing them to see if they can be falsified ... (ABSTRACT TRUNCATED)

journal_name

Pediatrics

journal_title

Pediatrics

authors

Meadow W,Lantos J

doi

10.1542/peds.101.4.e6

subject

Has Abstract

pub_date

1998-04-01 00:00:00

pages

E6

issue

4

eissn

0031-4005

issn

1098-4275

journal_volume

101

pub_type

杂志文章
  • Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures: an update.

    abstract::The safe sedation of children for procedures requires a systematic approach that includes the following: no administration of sedating medication without the safety net of medical supervision; careful presedation evaluation for underlying medical or surgical conditions that would place the child at increased risk from...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2006-2780

    authors: American Academy of Pediatrics.,American Academy of Pediatric Dentistry.,Coté CJ,Wilson S,Work Group on Sedation.

    更新日期:2006-12-01 00:00:00

  • Yield of chest radiography after removal of esophageal foreign bodies.

    abstract:OBJECTIVES:The aim of this study was to determine the benefit of routine postoperative chest radiography after removal of esophageal foreign bodies in children. METHODS:Medical records were reviewed of all patients evaluated with an esophageal foreign body at a single children's hospital over 10 years. Operative recor...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-3676

    authors: Fisher J,Mittal R,Hill S,Wulkan ML,Clifton MS

    更新日期:2013-05-01 00:00:00

  • Neurodevelopmental Outcomes in Infants With Birth Weight ≤500 g at 3 Years of Age.

    abstract:OBJECTIVES:To determine neurodevelopmental outcomes at 3 years of age in children born with a birth weight (BW) of ≤500 g. METHODS:Infants who were born with a BW of ≤500 g from 2003 to 2012 in the Neonatal Research Network of Japan and survived to discharge from the NICU were eligible in this study. The study populat...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-4286

    authors: Inoue H,Ochiai M,Sakai Y,Yasuoka K,Tanaka K,Ichiyama M,Kurata H,Fujiyoshi J,Matsushita Y,Honjo S,Nonaka K,Taguchi T,Kato K,Ohga S,Neonatal Research Network of Japan.

    更新日期:2018-12-01 00:00:00

  • Effects of continuity of care in infancy on receipt of lead, anemia, and tuberculosis screening.

    abstract:OBJECTIVES:The goals were (1) to examine the influence of continuity of care on delivery of lead, anemia, and tuberculosis screening in a cohort of Medicaid-enrolled children, (2) to determine whether well-child care continuity had a greater effect than continuity for all ambulatory visits, and (3) to investigate which...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-1497

    authors: Flores AI,Bilker WB,Alessandrini EA

    更新日期:2008-03-01 00:00:00

  • Vaccines are not associated with metabolic events in children with urea cycle disorders.

    abstract:BACKGROUND:Despite the success of childhood immunizations in prevention of infectious diseases, questions remain about the safety of vaccines in medically fragile children with inborn errors of metabolism such as urea cycle disorders (UCDs). Patients with UCDs are subject to hyperammonemic episodes (HAEs) after infecti...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-1628

    authors: Morgan TM,Schlegel C,Edwards KM,Welch-Burke T,Zhu Y,Sparks R,Summar M,Urea Cycle Disorders Consortium.

    更新日期:2011-05-01 00:00:00

  • Effect of age and sedative agent on the accuracy of bispectral index in detecting depth of sedation in children.

    abstract:OBJECTIVE:This study evaluated age- and sedative agent-related differences in bispectral index across observed sedation levels in a large sample of children < 18 years of age. PATIENTS AND METHODS:With institutional review board approval and waiver of consent, data from 4 independently conducted studies were combined ...

    journal_title:Pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1542/peds.2006-2577

    authors: Malviya S,Voepel-Lewis T,Tait AR,Watcha MF,Sadhasivam S,Friesen RH

    更新日期:2007-09-01 00:00:00

  • Evidence for an association between infant mortality and a carnitine palmitoyltransferase 1A genetic variant.

    abstract:OBJECTIVE:Alaska Native and other circumpolar indigenous populations have historically experienced high infant mortality rates, for unknown reasons. Through routine newborn screening, Alaskan and Canadian indigenous infants have been found to have a high frequency of a single sequence variant (c.1436C→T) in the gene co...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-0687

    authors: Gessner BD,Gillingham MB,Birch S,Wood T,Koeller DM

    更新日期:2010-11-01 00:00:00

  • Population case-control study of cerebral palsy: neonatal predictors for low-risk term singletons.

    abstract:OBJECTIVES:For singletons with cerebral palsy (CP) who were born at term, the goals were (1) to determine the proportion not admitted to a Special Care Unit/NICU (NICU), (2) to compare clinical descriptions of those admitted to NICUs and those not admitted, and (3) to identify neonatal predictors of CP among those not ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-1894

    authors: McIntyre S,Badawi N,Brown C,Blair E

    更新日期:2011-03-01 00:00:00

  • Annual summary of vital statistics--1982.

    abstract::Data for this article, as in previous reports, are drawn principally from the Monthly Vital Statistics Report, published by the National Center for Health Statistics. The international data come from the Demographic Yearbook and the quarterly Population and Vital Statistics Report, both published by the Statistical Of...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Wegman ME

    更新日期:1983-12-01 00:00:00

  • Parent diet modification, child activity, or both in obese children: an RCT.

    abstract:OBJECTIVES:Outcomes of childhood obesity interventions are rarely reported beyond 1 year. We hypothesized that the impact on the BMI z score from a child-centered physical-activity program in combination with a parent-centered dietary-modification program would be greater than either program conducted alone at 24 month...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2010-1518

    authors: Collins CE,Okely AD,Morgan PJ,Jones RA,Burrows TL,Cliff DP,Colyvas K,Warren JM,Steele JR,Baur LA

    更新日期:2011-04-01 00:00:00

  • Improving Discharge Efficiency in Medically Complex Pediatric Patients.

    abstract:BACKGROUND AND OBJECTIVE:Children with medical complexity have unique needs when facilitating transitions from hospital to home. Defining readiness for discharge is challenging, and preparation requires coordination of family, education, equipment, and medications. Our multidisciplinary team aimed to increase the perce...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-3832

    authors: Statile AM,Schondelmeyer AC,Thomson JE,Brower LH,Davis B,Redel J,Hausfeld J,Tucker K,White DL,White CM

    更新日期:2016-08-01 00:00:00

  • Low rates of influenza immunization in young children under Ontario's universal influenza immunization program.

    abstract:OBJECTIVES:To determine physician-administered influenza vaccine coverage for children aged 6 to 23 months in a jurisdiction with a universal influenza immunization program during 2002-2009 and to describe predictors of vaccination. METHODS:By using hospital records, we identified all infants born alive in Ontario hos...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-2441

    authors: Campitelli MA,Inoue M,Calzavara AJ,Kwong JC,Guttmann A

    更新日期:2012-06-01 00:00:00

  • Teaching clinical decision-making to pediatric residents in an era of managed care.

    abstract::The growth of managed care has brought a new focus on physician competency in the appropriate use of resources to help patients. The community of pediatric educators must improve residency curricula and teaching methodologies to ensure that graduates of their programs can effectively and efficiently meet the needs of ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Chessare JB

    更新日期:1998-04-01 00:00:00

  • The clinical phenotype of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria): case reports of 23 new patients.

    abstract:OBJECTIVES:To further define the clinical spectrum of the disease for pediatric and metabolic specialists, and to suggest that the general pediatrician and pediatric neurologist consider succinic semialdehyde dehydrogenase (SSADH) deficiency in the differential diagnosis of patients with (idiopathic) mental retardation...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.99.4.567

    authors: Gibson KM,Christensen E,Jakobs C,Fowler B,Clarke MA,Hammersen G,Raab K,Kobori J,Moosa A,Vollmer B,Rossier E,Iafolla AK,Matern D,Brouwer OF,Finkelstein J,Aksu F,Weber HP,Bakkeren JA,Gabreels FJ,Bluestone D,Barron T

    更新日期:1997-04-01 00:00:00

  • Community Access to Child Health (CATCH) in the historical context of Community Pediatrics.

    abstract:OBJECTIVES:As part of the evaluation of the American Academy of Pediatrics (AAP) Community Access to Child Health (CATCH), to 1) identify, retrospectively, the actual chronology of activities undertaken through CATCH, and 2) review its antecedents within the AAP, and its predecessor program-Healthy Children. METHODS:K...

    journal_title:Pediatrics

    pub_type: 历史文章,杂志文章

    doi:

    authors: Hutchins VL,Grason H,Aliza B,Minkovitz C,Guyer B

    更新日期:1999-06-01 00:00:00

  • Can an alternative umbilical arterial catheter solution and flush regimen decrease iatrogenic hemolysis while enhancing nutrition? A double-blind, randomized, clinical trial comparing an isotonic amino acid with a hypotonic salt infusion.

    abstract:OBJECTIVE:In the process of sampling blood through an umbilical arterial catheter (UAC), infant blood comes into stagnant contact with infusion solution in the "waste syringe" before being reinfused. We have previously demonstrated in vitro that this process is associated with less hemolysis of red blood cells (RBCs) w...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1542/peds.114.2.377

    authors: Jackson JK,Biondo DJ,Jones JM,Moor PJ,Simon SD,Hall RT,Kilbride HW

    更新日期:2004-08-01 00:00:00

  • Cardiovascular support for low birth weight infants and cerebral hemodynamics: a randomized, blinded, clinical trial.

    abstract:BACKGROUND:Maintaining adequate organ blood flow is the target of vasopressor treatment, but the impact of these measures on cerebral perfusion has not yet been evaluated systematically in a randomized, blinded, clinical trial. OBJECTIVES:To explore the effects on brain hemodynamics of 2 different inotropic agents use...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1542/peds.2004-1396

    authors: Pellicer A,Valverde E,Elorza MD,Madero R,Gayá F,Quero J,Cabañas F

    更新日期:2005-06-01 00:00:00

  • Infant sleep problems and postnatal depression: a community-based study.

    abstract:OBJECTIVES:To describe infant sleep patterns and investigate relationships between infant sleep problems and maternal well-being in the community setting. DESIGN:Cross-sectional community survey. Setting. Maternal and Child Health Centers in 3 middle-class local government areas in Melbourne, Australia. PARTICIPANTS:...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.107.6.1317

    authors: Hiscock H,Wake M

    更新日期:2001-06-01 00:00:00

  • Extracorporeal membrane oxygenation and conventional medical therapy in neonates with persistent pulmonary hypertension of the newborn: a prospective randomized study.

    abstract::Thirty-nine newborn infants with severe persistent pulmonary hypertension and respiratory failure who met criteria for 85% likelihood of dying were enrolled in a randomized trial in which extracorporeal membrane oxygenation (ECMO) therapy was compared with conventional medical therapy (CMT). In phase I, 4 of 10 babies...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: O'Rourke PP,Crone RK,Vacanti JP,Ware JH,Lillehei CW,Parad RB,Epstein MF

    更新日期:1989-12-01 00:00:00

  • Explaining the low risk of preterm birth among arab americans in the United States: an analysis of 617451 births.

    abstract:OBJECTIVES:Arab Americans have a lower risk for preterm birth than white Americans. We assessed factors that may contribute to the association between ethnicity and preterm birth risk in Michigan, the state with the largest concentration of Arab Americans in the United States. Factors assessed as potential contributors...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-1634

    authors: El-Sayed AM,Galea S

    更新日期:2009-03-01 00:00:00

  • Wide variation in reference values for aluminum levels in children.

    abstract:BACKGROUND:Some parents are requesting aluminum testing in their children with developmental issues. Although aluminum can be measured in plasma, serum, or urine, there is scant scientific information about normal ranges. We sought to determine the basis for laboratory reference ranges and whether these ranges are appl...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-3481

    authors: Zeager M,Woolf AD,Goldman RH

    更新日期:2012-01-01 00:00:00

  • Influenza burden for children with asthma.

    abstract:OBJECTIVE:The goal was to estimate the influenza disease burden among children with asthma and among healthy children by using active, laboratory-confirmed, population-based surveillance. METHODS:Children 6 to 59 months of age residing in 3 US counties who were hospitalized with acute respiratory illnesses or fever we...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-1053

    authors: Miller EK,Griffin MR,Edwards KM,Weinberg GA,Szilagyi PG,Staat MA,Iwane MK,Zhu Y,Hall CB,Fairbrother G,Seither R,Erdman D,Lu P,Poehling KA,New Vaccine Surveillance Network.

    更新日期:2008-01-01 00:00:00

  • Detection of coronavirus in the central nervous system of a child with acute disseminated encephalomyelitis.

    abstract::We present a case in which human coronavirus was detected in the cerebrospinal fluid of a child presumed to have acute disseminated encephalomyelitis. In murine models, coronavirus has been found to cause a chronic demyelinating condition that resembles multiple sclerosis. Additionally, there is in vitro evidence of h...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.113.1.e73

    authors: Yeh EA,Collins A,Cohen ME,Duffner PK,Faden H

    更新日期:2004-01-01 00:00:00

  • A rose by any other name? Objective knowledge, perceived knowledge, and adolescent male condom use.

    abstract:OBJECTIVE:To investigate the role of objective and perceived knowledge about condoms in adolescent males' condom use at first intercourse. METHODS:A longitudinal analysis was conducted of data from a nationally representative sample of 404 virgin male adolescents who were aged 15 to 17 years at wave 1 and reported bec...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-0139

    authors: Rock EM,Ireland M,Resnick MD,McNeely CA

    更新日期:2005-03-01 00:00:00

  • Allergy to beta-lactam antibiotics in children.

    abstract:BACKGROUND:Skin tests with soluble beta-lactams can be used to diagnose immediate and delayed hypersensitivity (HS) reactions to beta-lactam antibiotics. Very few studies have been performed with children with suspected beta-lactam allergy. In these studies, immediate HS to beta-lactams was diagnosed by skin tests in 4...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.104.4.e45

    authors: Ponvert C,Le Clainche L,de Blic J,Le Bourgeois M,Scheinmann P,Paupe J

    更新日期:1999-10-01 00:00:00

  • Severe perinatal Marfan syndrome.

    abstract::The cardiovascular manifestations of the Marfan syndrome in older children and adults have been well described. Clinical, radiographic, and echocardiographic data regarding three patients with severe perinatal Marfan syndrome are described. Two of these patients had the syndrome at birth and died in infancy. The syndr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gross DM,Robinson LK,Smith LT,Glass N,Rosenberg H,Duvic M

    更新日期:1989-07-01 00:00:00

  • Air pollution and infant death in southern California, 1989-2000.

    abstract:OBJECTIVE:We evaluated the influence of outdoor air pollution on infant death in the South Coast Air Basin of California, an area characterized by some of the worst air quality in the United States. METHODS:Linking birth and death certificates for infants who died between 1989 and 2000, we identified all infant deaths...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-0027

    authors: Ritz B,Wilhelm M,Zhao Y

    更新日期:2006-08-01 00:00:00

  • Risk of respiratory illness associated with day-care attendance: a nationwide study.

    abstract::The risk of respiratory and other illnesses in children (age groups: 6 weeks through 17 months, 18 through 35 months, and 36 through 59 months) in various types of day-care facilities was studied. Children considered exposed to day care were those who were enrolled in day care with at least one unrelated child for at ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Hurwitz ES,Gunn WJ,Pinsky PF,Schonberger LB

    更新日期:1991-01-01 00:00:00

  • The changing composition of the pediatric medical subspecialty workforce.

    abstract:OBJECTIVES:To characterize the composition of the pediatric subspecialty workforce in terms of the distribution of women and international medical graduates (IMGs) across pediatric medical subspecialties and to determine whether the proportions of board-certified pediatric subspecialists who are women or IMGs differ be...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-2446

    authors: Mayer ML,Preisser JS

    更新日期:2005-10-01 00:00:00

  • Nurse Home Visiting and Maternal Mental Health: 3-Year Follow-Up of a Randomized Trial.

    abstract:BACKGROUND:Poor mental health is recognized as one of the greatest global burdens of disease. Maternal mental health is crucial for the optimal health of mothers and their children. We examined the effects of an Australian Nurse Home Visiting (NHV) program (right@home), offered to pregnant women experiencing adversity,...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-025361

    authors: Goldfeld S,Bryson H,Mensah F,Gold L,Orsini F,Perlen S,Price A,Hiscock H,Grobler A,Dakin P,Bruce T,Harris D,Kemp L

    更新日期:2021-02-01 00:00:00