Abstract:
:We tested two hypotheses relating to the sensory deficit that follows a unilateral superior laryngeal nerve (SLN) lesion in an infant animal model. We hypothesized that it would result in (1) a higher incidence of aspiration and (2) temporal changes in sucking and swallowing. We ligated the right-side SLN in six 2-3-week-old female pigs. Using videofluoroscopy, we recorded swallows in the same pre- and post-lesion infant pigs. We analyzed the incidence of aspiration and the duration and latency of suck and swallow cycles. After unilateral SLN lesioning, the incidence of silent aspiration during swallowing increased from 0.7 to 41.5%. The durations of the suck containing the swallow, the suck immediately following the swallow, and the swallow itself were significantly longer in the post-lesion swallows, although the suck prior to the swallow was not different. The interval between the start of the suck containing a swallow and the subsequent epiglottal movement was longer in the post-lesion swallows. The number of sucks between swallows was significantly greater in post-lesion swallows compared to pre-lesion swallows. Unilateral SLN lesion increased the incidence of aspiration and changed the temporal relationships between sucking and swallowing. The longer transit time and the temporal coordinative dysfunction between suck and swallow cycles may contribute to aspiration. These results suggest that swallow dysfunction and silent aspiration are common and potentially overlooked sequelae of unilateral SLN injury. This validated animal model of aspiration has the potential for further dysphagia studies.
journal_name
Dysphagiajournal_title
Dysphagiaauthors
Ding P,Campbell-Malone R,Holman SD,Lukasik SL,Fukuhara T,Gierbolini-Norat EM,Thexton AJ,German RZdoi
10.1007/s00455-013-9448-ysubject
Has Abstractpub_date
2013-09-01 00:00:00pages
404-12issue
3eissn
0179-051Xissn
1432-0460journal_volume
28pub_type
杂志文章相关文献
DYSPHAGIA文献大全abstract::Pharyngeal high-resolution manometry (HRM) is at a point of entry into speech-language pathologist (SLP) clinical practice. However, the demographic characteristics of SLPs who are early adopters of HRM are unclear; perspectives of early adopters may shape how the technology is received by the field at large. We hypot...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-018-9941-4
更新日期:2019-06-01 00:00:00
abstract::Fifty-one patients with systemic sclerosis (scleroderma) underwent videofluoroscopy during barium swallow to evaluate the incidence of oropharyngeal deglutition abnormalities and to correlate the radiologic patterns of esophageal motility abnormalities with patients' clinical features. Thirteen patients (26%) showed s...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/BF02493531
更新日期:1991-01-01 00:00:00
abstract::The aim of this work was to assess the efficacy of external myotomy of the upper esophageal sphincter (UES) for oropharyngeal dysphagia. In the period 1991-2006, 28 patients with longstanding dysphagia and/or aspiration problems of different etiologies underwent UES myotomy as a single surgical treatment. The main sym...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-009-9236-x
更新日期:2010-09-01 00:00:00
abstract::The reliability of the modified Evans blue dye (MEBD) test for the detection of aspirated materials in patients with tracheostomy has been questioned. The videofluoroscopic swallow study (VFSS) has been the standard procedure used to detect aspiration, but there are known risks and the VFSS is not always an available ...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/PL00009596
更新日期:1999-07-01 00:00:00
abstract::Aspiration pneumonia is a major cause of morbidity and mortality among the elderly who are hospitalized or in nursing homes. Multiple risk factors for pneumonia have been identified, but no study has effectively compared the relative risk of factors in several different categories, including dysphagia. In this prospec...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/PL00009559
更新日期:1998-04-01 00:00:00
abstract::The approach to children with neurogenic dysphagia is unique due to their development, growth, and behavior. Multiple streams of development (cognitive, oral-motor, fine and gross motor) have direct and indirect effects on feeding. Provision of an appropriate feeding program requires that the multiple needs, abilities...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/BF02407131
更新日期:1989-01-01 00:00:00
abstract::The aim of this cross-sectional study is to evaluate the factors associated with patient-reported dysphagia in patients affected by locally advanced oropharyngeal cancer (OPC) treated with definitive intensity-modulated radiation therapy (IMRT) and concurrent chemotherapy (CHT), with or without induction CHT. We evalu...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-018-9913-8
更新日期:2019-02-01 00:00:00
abstract::Patient adherence to treatment recommendations is an important issue for healthcare providers, in a multitude of specialties, and is critical when assessing the efficacy and effectiveness of a particular treatment approach. Patients who have swallowing impairment often require complex and specific interventions requir...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-017-9852-9
更新日期:2018-04-01 00:00:00
abstract::The benefit of water protocols for individuals with thin liquid aspiration remains controversial, with mixed findings from a small number of randomized controlled trials (RCTs). This study aimed to contribute to the evidence of the effectiveness of water protocols with a particular emphasis on health outcomes, especia...
journal_title:Dysphagia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00455-016-9694-x
更新日期:2016-06-01 00:00:00
abstract::This pilot study examined the effect of a new head extension swallowing exercise (HESE) on submental muscle activity and tongue strength in healthy volunteers. Fifteen young adults (10 females and 5 males) were instructed to extend their head backwards as much as possible, and while watching the ceiling, swallowed the...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-016-9732-8
更新日期:2016-10-01 00:00:00
abstract::Use of high-flow oxygen via nasal cannula (HFO2-NC) is increasingly common in intensive care unit (ICU) settings. Despite the critical interface between respiration and swallowing, and the high acuity of patients in ICUs, the impact of HFO2-NC on feeding and swallowing is unknown. The present prospective, single-cente...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-015-9669-3
更新日期:2016-04-01 00:00:00
abstract::To compare two consecutive swallowing attempts to study if there is a difference in Rosenbek's penetration-aspiration scale (PAS) scores between the first and second swallowing attempt of the same bolus type in videofluoroscopic examination of swallowing (VFS). Additional aims include reflecting on which bolus sizes a...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-017-9814-2
更新日期:2017-10-01 00:00:00
abstract::During a videofluoroscopic swallowing study (VFSS), speech and language pathologists (SLPs) are potentially exposed to radiation. To effectively limit unnecessary exposure, SLPs performing VFSS are encouraged to actively shield themselves and to be monitored by radiation-monitoring badges. The aim of this research was...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-008-9151-6
更新日期:2008-12-01 00:00:00
abstract::Within the sphere of dysphagia management, there is a growing need for the development of noninvasive methods of quantification of swallowing disorders. The purpose of the present investigation was to determine if surface electromyogram (EMG) at the throat could be measured during swallowing. Surface EMG was measured ...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/BF00366380
更新日期:1996-07-01 00:00:00
abstract::A 36-year-old man who had sustained a closed head injury displayed extreme fear of being stimulated in the oral cavity, of being presented with foods, and of swallowing. The patient's fear increased his muscle tone and hypersensitivity in the facial and oral area, thereby preventing assessment of his dysphagia. We des...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/BF02493445
更新日期:1992-01-01 00:00:00
abstract::The adverse consequences of aspiration in regard to patient health and quality of life are well documented. It is generally accepted that the probability of aspiration is increased in patients with unilateral vocal fold motion impairment, however, the incidence and proposed mechanism of aspiration vary depending on th...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s004550000026
更新日期:2000-10-01 00:00:00
abstract::Dysphagia is common following total laryngectomy. Postlaryngectomy neopharyngeal diverticulae are known to cause postlaryngectomy dysphagia but are more frequently asymptomatic. We report a case presenting with late-onset postlaryngectomy dysphagia and a suprastomal swelling secondary to such a diverticulum. The patie...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-004-0015-4
更新日期:2004-10-01 00:00:00
abstract::Vomiting after feeding is a symptom of gastroesophageal reflux (GER) and of eosinophilic esophagitis (EE), which are considered to be a cause of infant feeding disorder. The objective of the present study was to evaluate swallowing in children with feeding disorder manifested by vomiting after feeding. Using clinical ...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-007-9122-3
更新日期:2008-06-01 00:00:00
abstract::Vallecular cysts are formed when the duct of a mucous gland or lingual tonsillar crypt is dilated owing to obstruction from inflammation, irritation, or trauma. Small cysts are usually asymptomatic; however, cyst growth results in dysphagia, odynophagia, and acute airway complications. As complete transoral laser exci...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-017-9796-0
更新日期:2017-10-01 00:00:00
abstract::A 17-year-old woman was evaluated for dysphagia. Radiologic study revealed a rigid segment 10 cm long in the midesophagus, which was found to be aperistaltic on manometric evaluation. The rest of the esophagus and the lower esophageal sphincter were manometrically normal. Four years later the patient was seen for eval...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/BF02493451
更新日期:1992-01-01 00:00:00
abstract::Visual imaging modalities, videofluoroscopic swallow study (VFSS) and fiberoptic endoscopic evaluation of swallow, for assessment of oropharyngeal dysphagia have been part of the speech language pathologist's (SLPs) armamentarium for the diagnosis and treatment of dysphagia for decades. Recently, the addition of high-...
journal_title:Dysphagia
pub_type: 杂志文章,评审
doi:10.1007/s00455-013-9494-5
更新日期:2014-02-01 00:00:00
abstract::Patients with obstructive sleep apnea syndrome (OSAS) are likely to exhibit an impaired swallowing reflex. However, mechanisms of disturbed swallowing reflex have not been determined. Because the upper-airway function is inhibited by hypoxia and hypercapnia, we examined the relationship between the swallowing function...
journal_title:Dysphagia
pub_type: 临床试验,杂志文章
doi:10.1007/s00455-001-0083-7
更新日期:2001-10-01 00:00:00
abstract::In amyotrophic lateral sclerosis (ALS) patients, dysphagia eventually occurs independent of time of onset. We studied dysphagia conditions in the early stage of ALS, principally at the oral phase. Videofluoroscopic and manometric studies were conducted on 11 patients (5 males and 6 females, age range = 47-82 years) wh...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-002-0074-3
更新日期:2003-01-01 00:00:00
abstract::The ability to measure normality and abnormality and to accurately assess true changes in swallowing function over time, is important for the management of dysphagia. Despite this, there is a paucity of information regarding the stability and reliability of measurements tools used for dysphagia research. As both head ...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-008-9181-0
更新日期:2009-06-01 00:00:00
abstract::Resting pressure at the upper oesophageal sphincter (UOS) has been reported to be susceptible to factors such as emotional stress or respiration. This exploratory study investigated the potential for behavioural modulation of UOS resting pressure in healthy adults to increase our understanding of volitional control of...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-020-10146-7
更新日期:2020-06-18 00:00:00
abstract::The purpose of this study was to investigate the relationships of four intensities of tactile-thermal application (TTA) to changes in duration of stage transition (DST) and performance on a newly designed scale of penetration and aspiration by groups of patients made dysphagic by stroke. Patients were randomly assigne...
journal_title:Dysphagia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/PL00009542
更新日期:1998-01-01 00:00:00
abstract::The influence of bolus volume and viscosity on the distribution of anterior lingual force during the oral stage of swallowing was investigated using a new force transducer technology. The maximum force amplitudes from 5 normal adults were measured simultaneously at the mid-anterior, right, and left lateral tongue marg...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/BF00417901
更新日期:1996-04-01 00:00:00
abstract::Dysphagia associated with radiotherapy for head and neck cancer is complex and can be difficult to treat. Videofluoroscopic swallow studies (VFSS) are the current gold-standard instrumented swallow assessment. High-resolution manometry (HRM) is an additional approach that provides objective measurements of swallowing-...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-020-10128-9
更新日期:2020-05-15 00:00:00
abstract::Infants < 51 weeks post-menstrual age (< 51 PMA) are often referred for modified barium swallow (MBS) studies for suspected silent aspiration (SA) given a possible association between SA and aspiration pneumonia. Infants this young are unlikely to have developed a mature laryngeal cough reflex, most likely rendering S...
journal_title:Dysphagia
pub_type: 杂志文章
doi:10.1007/s00455-019-10062-5
更新日期:2020-06-01 00:00:00
abstract::Successful oral intake of nutrition depends not only on the patient's ability to swallow efficiently and safely but also a number of cognitive, neurolinguistic, and behavioral variables. This paper reviews these competencies as they are integrated into the act of oral feeding and describes the types of disorders that ...
journal_title:Dysphagia
pub_type: 杂志文章,评审
doi:10.1007/BF02407266
更新日期:1990-01-01 00:00:00