Abstract:
:This spotlight review focuses on the second-generation proteasome inhibitor carfilzomib, which was recently approved by the U.S. Food and Drug Administration for treatment of relapsed and refractory multiple myeloma patients who have received at least 2 prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of the completion of the last therapy. This review focuses on clinical trial data leading to drug approval and provides advice for treating physicians who are now accessing this drug for patients.
journal_name
Bloodjournal_title
Bloodauthors
Kortuem KM,Stewart AKdoi
10.1182/blood-2012-10-459883subject
Has Abstractpub_date
2013-02-07 00:00:00pages
893-7issue
6eissn
0006-4971issn
1528-0020pii
blood-2012-10-459883journal_volume
121pub_type
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