Abstract:
:Up to now, the attention of ophthalmic surgeons has been focused mainly on the clinical results of epikeratophakia, demonstrating its safety, relative predictability, and capability of correcting a wide range of refractive errors. However, no prospective study has ever been undertaken to evaluate the influence of epikeratophakia on various physiologic and morphologic parameters of the cornea. The authors investigated some of these parameters prospectively in eight consecutive patients undergoing epikeratophakia with prelathed, lyophilized tissue. Fluorophotometric evaluation of the epithelial barrier function, corneal densitometry by means of Scheimpflug photography, and endothelial specular microscopy were performed preoperatively and 2, 4, 8, 12, and 24 weeks after epikeratophakia. The epithelial barrier function was shown to return to normal 4 weeks after surgery. The optical density of both the epi-lenses and the host corneas increased early after surgery, but was comparable to that of unoperated corneas 6 weeks postoperatively in all cases but one. The endothelial cell density was not altered by surgery in any patient. Despite the limited number of patients, this study indicates that most functional and morphologic parameters of the cornea are normal as early as 6 weeks after epikeratophakia in most cases.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Busin M,Spitznas M,Hockwin Odoi
10.1016/s0161-6420(90)32585-xsubject
Has Abstractpub_date
1990-03-01 00:00:00pages
330-3issue
3eissn
0161-6420issn
1549-4713pii
S0161-6420(90)32585-Xjournal_volume
97pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract:PURPOSE:To recognize discoid lupus erythematosus (DLE) as a treatable cause of chronic blepharoconjunctivitis. DESIGN:Retrospective observational case series. PARTICIPANTS:Records of 5 patients with biopsy-proven DLE were reviewed. METHODS:Clinical and pathology records were examined. MAIN OUTCOME MEASURES:Patients...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2005.01.035
更新日期:2005-05-01 00:00:00
abstract::Sixty-four consecutive patients with aphakic penetrating keratoplasty and penetrating keratoplasty combined with intracapsular cataract extraction were reviewed in a prospective fashion with a minimum of a one-year follow-up. Five were lost to follow-up. There were seven graft failures at the end of one year. Five of ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(80)35187-7
更新日期:1980-07-01 00:00:00
abstract:PURPOSE:Intraoperative floppy iris syndrome (IFIS) caused by systemic alpha-blockers has been associated with an increased risk of cataract surgical complications when the surgeon was unaware of the medication history and did not anticipate its occurrence. This study was undertaken to evaluate the surgical outcomes and...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2007.01.011
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:To develop a clinical classification system for age-related macular degeneration (AMD). DESIGN:Evidence-based investigation, using a modified Delphi process. PARTICIPANTS:Twenty-six AMD experts, 1 neuro-ophthalmologist, 2 committee chairmen, and 1 methodologist. METHODS:Each committee member completed an o...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.10.036
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:One assumption of the uniocular drug trial in glaucoma management is that fellow-eye pairs exhibit symmetric intraocular pressure (IOP) responses when both eyes are treated with the same topical IOP-lowering medication. The purpose of this study was to determine if this assumption is true. DESIGN:Observational...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2004.11.028
更新日期:2005-04-01 00:00:00
abstract:CASE REPORT:An 85-year-old woman had a bluish tumor medially on the margin of the left upper eyelid. Malignant melanoma of the conjunctiva was presumed; the lesion was excised and submitted for routine histopathologic examination. There are no signs of recurrence or metastatic disease after follow-up for 1 year. METHO...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(93)31412-0
更新日期:1993-11-01 00:00:00
abstract:PURPOSE:The purpose of the study was to determine long-term results of involutional entropion repair by a modified corncrib (inverted T) procedure with a Quickert suture. METHODS:A retrospective review of consecutive patients with involutional entropion who underwent repair by a modified corncrib procedure from Januar...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(97)30284-x
更新日期:1997-03-01 00:00:00
abstract:PURPOSE:To illustrate the role of surgical removal of iris nodules (granulomas) in the management of sarcoid uveitis. STUDY DESIGN:Two interventional case reports. METHODS:The authors describe the clinical course of two 10-year-old males with long-standing granulomatous uveitis refractory to medical antiinflammatory ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(01)00601-7
更新日期:2001-07-01 00:00:00
abstract::A clinicopathologic study of multiple extramacular drusen (MED) was performed on 784 eyes of 412 consecutive autopsies and on 100 eyes of 50 consecutive patients with MED. The clinical and histopathologic characteristics of MED and its correlation with reticular degeneration of the pigment epithelium (RDPE) and with m...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33615-7
更新日期:1986-08-01 00:00:00
abstract::A case of preseptal cellulitis caused by Mycobacterium intracellulare is presented. A 56-year-old white woman developed erythema, induration, and tenderness of the lids of her right eye after chalazion removal, which did not respond to three weeks of broad spectrum antibiotics. Incision and drainage with biopsy reveal...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(82)34762-4
更新日期:1982-05-01 00:00:00
abstract::We studied 30 patients with opacifications of the posterior capsule to determine if the potential acuity meter (PAM) could accurately predict final visual outcome after Nd:YAG discussion. The final visual acuity was within one line of the PAM prediction in 22 of 30 patients (73%), better by two or more lines in seven ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33723-0
更新日期:1986-03-01 00:00:00
abstract:PURPOSE:To report the frequency and relationship of eyelid retraction, lid lag, lagophthalmos, and von Graefe's sign in a group of patients with Graves' ophthalmopathy and compare these findings to those in a group of normal individuals. DESIGN:Retrospective comparative cohort study. PARTICIPANTS:Fifty consecutive Gr...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2007.07.027
更新日期:2008-06-01 00:00:00
abstract::We performed morphologic and tissue culture studies on scleral tissues obtained from a nanophthalmic patient. Seen by light and electron microscopy, collagens in these unusually thick scleral tissues were arranged in irregularly interlacing bundles. The size of the collagen fibers was more variable than that observed ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33704-7
更新日期:1986-04-01 00:00:00
abstract:PURPOSE:To characterize the demographics of patients with dacryolithiasis and to compare patients who have canalicular concretions with patients who have lacrimal sac and duct dacryoliths. DESIGN:Comparative case series study and literature review. PARTICIPANTS:A total of 327 consecutive patients undergoing external ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.04.029
更新日期:2009-11-01 00:00:00
abstract::Twelve consecutive patients with optic neuritis of unknown etiology treated with 250 to 500 mg methylprednisolone every 6 hours are described. All patients improved, some dramatically and rapidly. Patients with swollen discs and visual loss for less than 6 weeks improved uniformly, rapidly, and completely. In some pat...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(88)33220-3
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:To review the evidence regarding the safety and efficacy of current anti-vascular endothelial growth factor (VEGF) pharmacotherapies for the treatment of diabetic macular edema (DME). METHODS:Literature searches last were conducted in September 2011, in PubMed with no date restrictions, limited to articles p...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ophtha.2012.07.058
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To prospectively examine the change in upper eyelid position on downgaze in patients with blepharoptosis. METHODS:Upper eyelid margin to corneal light reflex distance (uMRD) was measured in primary gaze and in 30 degrees to 40 degrees downgaze in 50 consecutive patients with acquired ptosis and 10 consecutive ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(95)30837-8
更新日期:1995-10-01 00:00:00
abstract:PURPOSE:To examine whether glaucoma status or measures of visual function affected by glaucoma are associated with self-reported difficulty with vision-intensive tasks in a population-based study. DESIGN:Cross-sectional study. PARTICIPANTS:One thousand one hundred sixty individuals who participated in the fourth roun...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2007.04.050
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:The Accreditation Council for Graduate Medical Education (ACGME) has mandated that all residency programs implement an assessment process of 6 core competencies. Assessment of surgical competence is also included in the mandate. We describe our local efforts to meet this new mandate. DESIGN:Systematic litera...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2004.04.021
更新日期:2004-10-01 00:00:00
abstract:PURPOSE:The authors quantified the vascular resistance for venous outflow in central retinal vein occlusion (CRVO). METHODS:The blood velocity in the central retinal vein (CRV) and central retinal artery (CRA) was measured by pulsed Doppler sonography (4-Mhz probe), and the pulse curve of the intraocular pressure (IOP...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(97)30255-3
更新日期:1997-04-01 00:00:00
abstract::A retrospective clinicopathologic review of 105 cases of sympathetic ophthalmia showed histologic features of prognostic significance and evaluated the role of therapy. Classic descriptions omit retinal changes, but 58.0% of our cases had retinal detachment and 42.2% showed intraretinal inflammation. The optic nerve a...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(80)35270-6
更新日期:1980-02-01 00:00:00
abstract:OBJECTIVE:To describe multifocal electroretinogram (mfERG) responses in 2 patients with nonorganic visual loss and in 11 eyes of 6 healthy persons who suppressed their mfERG responses. DESIGN:Observational case series. METHODS:The mfERG results were recorded in all individuals using the Veris Science 4.2 instrument. ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2003.04.011
更新日期:2004-01-01 00:00:00
abstract::It was the purpose of this study to determine whether age could be used to predict central endothelial cell count in preoperative cataract patients aged 40 to 90. Three separate series of cell counts on a total of almost 3,000 eyes were performed and analyzed regarding age relationship. Although statistically endothel...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(80)35149-x
更新日期:1980-09-01 00:00:00
abstract:PURPOSE:The authors evaluated the relative nerve fiber layer height changes in glaucomatous eyes after reduction of intraocular pressure (IOP) after trabeculectomy using image analysis techniques. METHODS:Optic disc topography and relative nerve fiber layer height of 12 eyes of 12 patients with chronic open-angle glau...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(93)31497-1
更新日期:1993-08-01 00:00:00
abstract::Experiments were performed to determine the absorption by and transmission through blood of argon blue-green (ABG) and green (AG) and krypton red (KR) laser light. Krypton was transmitted better through intact erythrocytes than argon. The difference between krypton and argon was greater if the erythrocytes contained o...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)34083-6
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:Nonmydriatic fundus photography by non-ophthalmic-trained personnel has recently been shown to be a potential alternative to direct ophthalmoscopy in the emergency department (ED). We evaluated the reliability of a novel quality rating scale and applied this scale to nonmydriatic fundus photographs taken duri...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.09.013
更新日期:2012-03-01 00:00:00
abstract::Isolated involvement of the optic nerve with metastatic tumor is uncommon. A 19-year-old man had a midline cerebellar medulloblastoma; a gross total removal was performed. He received postoperative radiation therapy to the whole brain, posterior fossa, and craniospinal axis. A progressive optic neuropathy developed 28...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32912-5
更新日期:1989-02-01 00:00:00
abstract::An integrated ophthalmic office computer system is now functional at five sites. The system automates clerical functions such as appointment scheduling, billing, and preparation of doctors' schedules and insurance forms. It eliminates the need for filing and storage of records. The medical system records the history a...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)35060-x
更新日期:1981-02-01 00:00:00
abstract:PURPOSE:To assess the status of choriocapillaris in eyes with macular atrophy secondary to age-related macular degeneration (AMD) (geographic atrophy [GA]) and Stargardt disease (STGD) using optical coherence tomography angiography (OCTA). DESIGN:Prospective, observational case series. PARTICIPANTS:A total of 14 pati...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2016.05.041
更新日期:2016-09-01 00:00:00
abstract::Thirteen keratophakia patients were followed for 13 to 35 months. Eighteen cases of hyperopic keratomileusis or hyperopic keratomileusis using preserved corneal tissue were followed for 2 to 30 months. All 13 patients who underwent keratophakia achieved 20/50 or better acuity. All seven patients having hyperopic kerat...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)34957-4
更新日期:1981-08-01 00:00:00