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Sex-related differences in peri- and post-ablation clinical data for patients with atrial flutter.

Abstract：

UNLABELLED:Sex-related differences were not reported for the atrial flutter (AF). The purpose of the study was to look for the influence of gender on indications, clinical data and long-term results of AFl ablation. METHODS:985 patients, [227 females (23%)] were referred for radiofrequency AFl ablation. Clinical history, echocardiography were collected. Patients were followed from 3 months to 10 years. RESULTS:Age of women and men was similar (65.5 ± 12 vs 64 ± 11.5 years). Underlying heart disease (HD) was as frequent in women as men (77.5 vs 77%), but women had more congenital HD (10 vs 2%;p<0.001), valvular HD (18 vs 10%;p<0.002), hypertensive HD (24 vs 18%;p<0.05), and less chronic lung disease (5 vs 10%;p<0.01), and ischemic HD (5 vs 20%;p<0.001). Atrial fibrillation (AF) history was more frequent in women (36 vs 27%;p<0.001). AFl-related tachycardiomyopathy (4.5 vs 8%;p<0.03) was more frequent, but 1/1 AFl (10 vs 6%;p=NS) as frequent. Failure of ablation (16 vs 10%;p<0.01), ablation-related major complications (3.5 vs 0.9%;p<0.005) were more frequent in women. After 3 ± 3 years, AFl recurrences were as frequent in women and men (10 vs 14%), AF occurrence more frequent in women (34 vs 19.5%; p<0.001). After excluding patients with previous AF, AF risk remained higher in women (19 vs 12%; p<0.004). CONCLUSIONS:In patients admitted for ablation, AFL was less common in women than in men, despite similar age and similarly prevalent HD. More than men, women had frequent AF history, a higher risk of failure of ablation and AFl ablation-related major complications and a higher risk of AF after ablation.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Brembilla-Perrot B,Huttin O,Manenti V,Benichou M,Sellal JM,Zinzius PY,Beurrier D,Schwartz J,Laporte F,de Chillou C,Andronache M,Cismaru G,Pauriah M,Selton O,Louis P,Terrier de la Chaise A

doi

10.1016/j.ijcard.2012.12.088

subject

Has Abstract

pub_date

2013-10-03 00:00:00

pages

1951-4

issue

3

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(12)01732-9

journal_volume

168

pub_type

杂志文章

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