Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.

abstract：BACKGROUND:Subthreshold depression is a highly prevalent condition and a risk factor for developing a major depressive episode. Internet-based cognitive behaviour therapy may be a promising approach for the treatment of subthreshold depression. The current study had two aims: (1) to determine whether an internet-based ...

journal_title：Psychological medicine

authors： Spek V,Nyklícek I,Smits N,Cuijpers P,Riper H,Keyzer J,Pop V

更新日期：2007-12-01 00:00:00

abstract：:Seventy eight men were assessed one month before coronary artery bypass graft surgery using standardized measures of psychiatric morbidity and personality as well as a measure of emotional expression (the CECS). All patients had at least one coronary vessel occluded by 75% or more of its diameter, and functional capac...

journal_title：Psychological medicine

authors： Bass C,Akhras F

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:The prevalence of anxiety and mood disorders in adolescents is a growing public health concern worldwide. Given the high rates of drop-out and limited resources available in psychiatric settings, the importance of engaging adolescents in evidence-based treatments cannot be understated. The aim of the study w...

journal_title：Psychological medicine

authors： Dean S,Britt E,Bell E,Stanley J,Collings S

更新日期：2016-07-01 00:00:00

abstract：:The Eating Attitudes Test (EAT) and General Health Questionnaire (GHQ) have been validated in an unselected population of 15-year-old South London schoolgirls. Scores on the questionnaires were compared with the results of standard interview. The EAT was found to be an efficient screening instrument for abnormal eatin...

journal_title：Psychological medicine

authors： Mann AH,Wakeling A,Wood K,Monck E,Dobbs R,Szmukler G

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:The mechanisms that contribute to emotion dysregulation in anxiety disorders are not well understood. Two common disorders, generalized anxiety disorder (GAD) and panic disorder (PD), were examined to test the hypothesis that both disorders are characterized by hypo-activation in prefrontal cortex (PFC) duri...

journal_title：Psychological medicine

authors： Ball TM,Ramsawh HJ,Campbell-Sills L,Paulus MP,Stein MB

更新日期：2013-07-01 00:00:00

abstract：:Inhibition of central dopamine functions appears to be a common basic property of antipsychotic drugs. The mesolimbic and nigrostriatal portions of the dopaminergic system are probably the main targets of these drugs for the mental and the extrapyramidal actions respectively. Dopaminergic hyperfunction, induced by amp...

journal_title：Psychological medicine

authors： Carlsson A

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:There is uncertainty about the incidence of breakthrough psychosis in treatment adherent patients, and the role that factors, such as cumulative antipsychotic exposure, play in this phenomenon. METHODS:In a nationwide cohort of individuals treated for schizophrenia-spectrum disorders in Finland between 1 Ja...

journal_title：Psychological medicine

authors： Rubio JM,Taipale H,Correll CU,Tanskanen A,Kane JM,Tiihonen J

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Research on the structure of co-morbidity among common mental disorders has largely focused on current prevalence rather than on the development of co-morbidity. This report presents preliminary results of the latter type of analysis based on the US National Comorbidity Survey Replication Adolescent Suppleme...

journal_title：Psychological medicine

authors： Kessler RC,Avenevoli S,McLaughlin KA,Green JG,Lakoma MD,Petukhova M,Pine DS,Sampson NA,Zaslavsky AM,Merikangas KR

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:The goal of this study is to determine the association between panic attacks in adolescence and the risk of personality disorders during young adulthood. METHOD:Data were drawn from the Children in the Community Study, a longitudinal epidemiological study of psychopathology across the life-course in 717 indi...

journal_title：Psychological medicine

authors： Goodwin RD,Brook JS,Cohen P

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Childhood trauma is a risk factor for psychosis. Deficits in response inhibition are common to psychosis and trauma-exposed populations, and associated brain functions may be affected by trauma exposure in psychotic disorders. We aimed to identify the influence of trauma-exposure on brain activation and func...

journal_title：Psychological medicine

authors： Quidé Y,O'Reilly N,Watkeys OJ,Carr VJ,Green MJ

更新日期：2018-07-01 00:00:00

abstract：:Bilateral electrodermal orienting responses were measured to repeated auditory stimuli in schizophrenic patients and controls. In 3 studies phasic activity to moderate intensity sounds of patients on no drugs or phenothiazines was predominantly hyper- or hypo-responsive. Controls showed moderate or slow habituation. P...

journal_title：Psychological medicine

authors： Gruzelier J,Connolly J,Eves F,Hirsch S,Zaki S,Weller M,Yorkston N

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:There is an emerging consensus in developmental psychopathology that irritable youth are at risk for developing internalizing problems later in life. The current study explored if irritability in youth is multifactorial and the impact of irritability dimensions on psychopathology outcomes in adulthood. METH...

journal_title：Psychological medicine

authors： Hawes MT,Carlson GA,Finsaas MC,Olino TM,Seely JR,Klein DN

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Expressed emotion (EE) measured from relatives and informal carers has been consistently demonstrated to be associated with clinical outcome in schizophrenic patients. There have also been published studies that have investigated EE in professional carers that have suggested that the quality of the relations...

journal_title：Psychological medicine

authors： Tattan T,Tarrier N

更新日期：2000-01-01 00:00:00

abstract：:Forty-eight couples with a presenting problem of female sexual unresponsiveness were treated in a controlled study using a balanced factorial design. The factors varied in this design were medication (testosterone or placebo), treatment frequency (weekly or monthly sessions), and the number of therapists involved (one...

journal_title：Psychological medicine

authors： Mathews A,Whitehead A,Kellett J

更新日期：1983-02-01 00:00:00

abstract：:Bullying victimization is a topic of concern for youths, parents, school staff and mental health practitioners. Children and adolescents who are victimized by bullies show signs of distress and adjustment problems. However, it is not clear whether bullying is the source of these difficulties. This paper reviews empiri...

journal_title：Psychological medicine

authors： Arseneault L,Bowes L,Shakoor S

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:This study investigated factors contributing to suspected offending behaviour by adults with a history of learning disabilities taken into custody at a city police station. METHODS:Adults charged with offences, and/or leaving custody, during a defined period, were identified as having a possible learning di...

journal_title：Psychological medicine

authors： Winter N,Holland AJ,Collins S

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Little research has examined genetic and environmental contributions to psychopathic personality traits. Additionally, no studies have examined etiological connections between psychopathic traits and the broad psychopathological domains of internalizing (mood and anxiety) and externalizing (antisocial behavi...

journal_title：Psychological medicine

authors： Blonigen DM,Hicks BM,Krueger RF,Patrick CJ,Iacono WG

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Recent cross-sectional studies have shown psychotic experiences (PEs) are associated with suicidal ideation and behaviours. We aimed to examine associations between psychotic experiences (including persistent PE), and contemporaneous and incident non-suicidal self-injury (NSSI) and suicide attempts. METHOD:...

journal_title：Psychological medicine

authors： Martin G,Thomas H,Andrews T,Hasking P,Scott JG

更新日期：2015-01-01 00:00:00

abstract：:One hundred and nineteen primiparae, who were routinely attending ante-natal clinics, were interviewed repeatedly between the 12th and 36th weeks of their pregnancies. The incidence of depression was highest in the first trimester and, overall, about a fifth of the sample was found to be suffering from clinically sign...

journal_title：Psychological medicine

authors： Kumar R,Robson K

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Compassion-focused therapy (CFT) is a relatively novel form of psychotherapy that was developed for people who have mental health problems primarily linked to high shame and self-criticism. The aim of this early systematic review was to draw together the current research evidence of the effectiveness of CFT ...

journal_title：Psychological medicine

authors： Leaviss J,Uttley L

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:A randomized trial of a primary care-based intervention to prevent depression relapse resulted in improved adherence to long-term antidepressant medication and depression outcomes. We evaluated the effects of this intervention on behavioural processes and identified process predictors of improved depressive ...

journal_title：Psychological medicine

authors： Ludman E,Katon W,Bush T,Rutter C,Lin E,Simon G,Von Korff M,Walker E

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Sertraline has a proved efficacy in post-traumatic stress disorder (PTSD), but it is unknown which symptoms respond or in what sequence this occurs. Such information might be useful clinically and heuristically. METHOD:The study examined the effects of sertraline on the individual symptoms of PTSD. It also ...

journal_title：Psychological medicine

authors： Davidson JR,Landerman LR,Farfel GM,Clary CM

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Although psychiatric patients with eating disorders are known to be at risk for a variety of health problems, relatively little is known about eating disorders and associated health problems in other populations. An epidemiological study was conducted to investigate health problems and impairment associated ...

journal_title：Psychological medicine

authors： Johnson JG,Spitzer RL,Williams JB

更新日期：2001-11-01 00:00:00

abstract：:Difficulties in set-shifting are commonly reported in both autism spectrum disorder (ASD) and anorexia nervosa (AN) populations. Despite this, it is not known whether this cognitive profile persists across different ages, or whether the profiles seen in ASD and AN are comparable. This systematic review and meta-analys...

journal_title：Psychological medicine

authors： Westwood H,Stahl D,Mandy W,Tchanturia K

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Epidemiological evidence suggests a link between cannabis use and psychosis. A variety of factors have been proposed to mediate an individual's vulnerability to the harmful effects of the drug, one of which is their psychosis proneness. We hypothesized that highly psychosis-prone individuals would report mor...

journal_title：Psychological medicine

authors： Mason O,Morgan CJ,Dhiman SK,Patel A,Parti N,Patel A,Curran HV

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Multiple studies have found Conscientiousness to be protective against dementia. The purpose of this study is to identify which specific aspects, or facets, of Conscientiousness are most protective against cognitive impairment and whether these associations are moderated by demographic factors and/or genetic...

journal_title：Psychological medicine

authors： Sutin AR,Stephan Y,Terracciano A

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:No studies have reported on how to relieve distress or relax in medical health workers while wearing medical protective equipment in coronavirus disease 2019 (COVID-19) pandemic. The study aimed to establish which relaxation technique, among six, is the most feasible in first-line medical health workers wear...

journal_title：Psychological medicine

authors： Zhang H,Li A,Zhu B,Niu Y,Ruan Z,Liu L,Gao X,Wang K,Yin L,Peng M,Xue Q,Leng H,Min B,Tian Q,Wang C,Yang Y,Zhu Z,Si T,Li W,Shangguan F,Hong X,Chang H,Song H,Li D,Jia L,Dong H,Wang Y,Cosci F,Wang H

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:The importance of genetic factors in the aetiology of manic-depressive illness (MDI) has been repeatedly confirmed and indicators of vulnerability to the illness in families with affective disorders are needed. Abnormal event-related potentials (ERP) may be markers of genetic vulnerability to mental illness....

journal_title：Psychological medicine

authors： Pierson A,Jouvent R,Quintin P,Perez-Diaz F,Leboyer M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Many preschool-age children meet criteria for psychiatric disorders, and rates approach those observed in later childhood and adolescence. However, there is a paucity of longitudinal research examining the outcomes of preschool diagnoses. METHODS:Families with a 3-year-old child (N = 559) were recruited fro...

journal_title：Psychological medicine

authors： Finsaas MC,Bufferd SJ,Dougherty LR,Carlson GA,Klein DN

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Attentional difficulties reported in individuals with anorexia nervosa (AN) may be due to preferential processing of disease-salient stimuli at a pre-attentive or at a conscious level or to a general problem in attention. Attentional difficulties may be associated with duration of illness. METHOD:Female par...

journal_title：Psychological medicine

authors： Dickson H,Brooks S,Uher R,Tchanturia K,Treasure J,Campbell IC

更新日期：2008-12-01 00:00:00