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Lysosomal tartrate sensitive acid phosphatase deficiency in cells which contain lysosomal "high uptake forms".

Abstract：

:The catalytic and immunological properties of acid phosphatases (EC 3.1.3.2.) in different tissues were studied. It was demonstrated that high uptake forms of lysosomal enzymes like beta-galactosidase isolated from human platelets and bovine testis are mature enzymes, which have not lost their mannose-6phosphate marker. The results presented indicate that this phenomenon is related to a low activity or the complete absence of the lysosomal tartrate sensitive acid phosphatase activity in the tissues concerned.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Hu P,Parenti G,Keulemans J,Hoogeveen AT

doi

10.1016/0006-291x(90)92055-5

subject

Has Abstract

pub_date

1990-03-16 00:00:00

pages

520-7

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(90)92055-5

journal_volume

167

pub_type

杂志文章

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