Hepatitis C viral kinetics: the past, present, and future.

Abstract:

:Mathematical modeling of hepatitis C viral kinetics has been an important tool in understanding hepatitis C virus (HCV) infection dynamics and in estimating crucial in vivo parameters characterizing the effectiveness of HCV therapy. Because of the introduction of direct-acting antiviral agents, there is a need to extend previous models so as to understand, characterize, and compare various new HCV treatment regimens. Here we review recent modeling efforts in this direction.

journal_name

Clin Liver Dis

journal_title

Clinics in liver disease

authors

Chatterjee A,Smith PF,Perelson AS

doi

10.1016/j.cld.2012.09.003

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

13-26

issue

1

eissn

1089-3261

issn

1557-8224

pii

S1089-3261(12)00099-2

journal_volume

17

pub_type

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