Abstract：
:During an epidemic of cholera in Guinea, West Africa, in 1986, the authors conducted two studies of risk factors for transmission. In the capital city, 35 hospitalized cholera patients were more likely than 70 neighborhood-matched controls to have eaten leftover peanut sauces (odds ration (OR) = 3.1, 95% confidence interval (CI) 1.2-8.2), but less likely to have eaten tomato sauces (OR = 0.2, 95 percent CI 0.1-0.9). Hand washing with soap before meals by all family members protected against cholera (OR = 0.2, 95 percent CI 0.02-0.96), suggesting that persons asymptomatically infected with Vibrio cholerae 01 may have been the initial source for contamination of the leftover foods. Laboratory studies demonstrated that V. cholerae multiplied rapidly in peanut sauce (pH 6.0), but not in the more acidic tomato sauce (pH 5.0). In an outbreak of cholera-like illness after a rural funeral, illness was strongly associated with eating a rice meal served over many hours without reheating. These studies demonstrated that, in this epidemic, many cases of severe cholera were associated with eating specific cooked foods that could support bacterial growth after contamination of these foods with V. cholerae within the household. Epidemic control efforts should include identification of high-risk foods and promotion of simple changes in food handling behaviors to lower the risk of foodborne transmission.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
St Louis ME,Porter JD,Helal A,Drame K,Hargrett-Bean N,Wells JG,Tauxe RVdoi
10.1093/oxfordjournals.aje.a115556subject
Has Abstractpub_date
1990-04-01 00:00:00pages
719-28issue
4eissn
0002-9262issn
1476-6256journal_volume
131pub_type
杂志文章abstract：:For the first wave of pandemic influenza or a bioterrorist influenza attack, antiviral agents would be one of the few options to contain the epidemic in the United States until adequate supplies of vaccine were available. The authors use stochastic epidemic simulations to investigate the effectiveness of targeted anti...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwh092
更新日期：2004-04-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 评论,杂志文章
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journal_title：American journal of epidemiology
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更新日期：2014-11-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a008976
更新日期：1996-10-01 00:00:00
abstract：:A cohort of 888 rural, nonaboriginal persons with non-insulin-dependent diabetes mellitus identified in Western Australia through surveys in 1978-1982 were followed for death until the end of 1986. A total of 257 deaths were observed. Excess mortality in this cohort as compared with the general Australian population w...
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更新日期：1992-03-15 00:00:00
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更新日期：2001-07-01 00:00:00
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更新日期：2004-02-15 00:00:00
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pub_type： 杂志文章
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更新日期：2009-08-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2005-06-15 00:00:00
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pub_type： 杂志文章
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更新日期：2018-06-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113036
更新日期：1980-11-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116278
更新日期：1992-02-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwr037
更新日期：2011-07-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a008737
更新日期：1996-02-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114027
更新日期：1985-04-01 00:00:00
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journal_title：American journal of epidemiology
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journal_title：American journal of epidemiology
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journal_title：American journal of epidemiology
pub_type： 杂志文章,随机对照试验
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更新日期：2014-09-01 00:00:00
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更新日期：2012-09-01 00:00:00
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更新日期：1995-12-01 00:00:00
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journal_title：American journal of epidemiology
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更新日期：1993-01-15 00:00:00
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journal_title：American journal of epidemiology
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更新日期：1989-03-01 00:00:00
