Newly designed bioabsorbable substitute for the treatment of diaphragmatic defects.

Abstract:

PURPOSE:Earlier studies have investigated the suitability of various materials and autologous grafts for the repair of diaphragmatic defects. Our group investigated the feasibility of using an artificial diaphragm (AD) to repair wide diaphragmatic defects. METHODS:Twelve pigs were laparotomized and, in each pig, a defect was fashioned by resecting a round 8-cm diameter hole in the left diaphragm. Next, the defect was repaired by implanting an AD. The animals were relaparotomized 8 or 24 weeks after implantation for gross, histological and radiological observation of the implanted sites. RESULTS:All recipient animals survived until killing for evaluation. Chest X-ray examinations showed no differences between the preoperative diaphragms and the grafted diaphragms at 8 and 24 weeks after implantation. At 8 weeks after implantation, the implanted sites exhibited fibrous adhesions to the liver and lungs without deformities or penetrations. Parts of the surface tissue at the graft sites had a varnished appearance similar to those of the native diaphragm. Histology performed at 8 weeks detected no trace of the ADs in the graft sites; however, numerous inflammatory cells and profuse fibrous connective tissue were observed. At 24 weeks after implantation, no differences were found in the thorax between the areas with the grafts and the unaffected areas. Histology of the graft sites in the thorax confirmed growth of mesothelial cells similar to that observed in the native diaphragm. CONCLUSIONS:Artificial diaphragms can be a novel substitute for diaphragmatic repair.

journal_name

Surg Today

journal_title

Surgery today

authors

Aikawa M,Miyazawa M,Okamoto K,Toshimitsu Y,Okada K,Akimoto N,Ueno Y,Koyama I,Ikada Y

doi

10.1007/s00595-012-0414-3

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

1298-304

issue

11

eissn

0941-1291

issn

1436-2813

journal_volume

43

pub_type

杂志文章
  • Regulation of methionine adenosyltransferase activity by the glutathione level in rat liver during ischemia-reperfusion.

    abstract::Hepatic ischemia was induced by clamping the hepatic artery, portal vein, and bile duct. After 15 min of ischemia, the hepatic glutathione (GSH) content rapidly decreased. On the other hand, after the start of reperfusion, the hepatic GSH levels promptly increased and reached a peak at about 1 h, and thereafter decrea...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/PL00010035

    authors: Ito K,Miwa N,Hagiwara K,Yano T,Shimizu-Saito K,Goseki N,Iwai T,Horikawa S

    更新日期:1999-01-01 00:00:00

  • Postprandial hyperglycemia after a gastrectomy and the prediabetic state: a comparison between a distal and total gastrectomy.

    abstract:PURPOSE:Postprandial hyperglycemia is recognized as an important risk factor for developing type 2 diabetes; it is also common in patients after a gastrectomy and is likely to become exacerbated after a total gastrectomy rather than after a distal gastrectomy. In this study, we investigated the glucose and insulin resp...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-007-3711-5

    authors: Yamamoto H,Tsuchihashi H,Akabori H,Naitoh H,Maegawa H,Tani T

    更新日期:2008-01-01 00:00:00

  • LINE-1 methylation level and prognosis in pancreas cancer: pyrosequencing technology and literature review.

    abstract:PURPOSE:Global DNA hypomethylation plays an important role in genomic instability and carcinogenesis. The long interspersed nucleotide element-1 (LINE-1) methylation level is a good surrogate marker of the global DNA methylation level. Previously, we demonstrated a strong relationship between LINE-1 hypomethylation and...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-017-1539-1

    authors: Yamamura K,Kosumi K,Baba Y,Harada K,Gao F,Zhang X,Zhou L,Kitano Y,Arima K,Kaida T,Takeyama H,Higashi T,Imai K,Hashimoto D,Chikamoto A,Tan X,Baba H

    更新日期:2017-12-01 00:00:00

  • Clinical significance of surgical resection of metastatic lymph nodes from hepatocellular carcinoma.

    abstract:PURPOSE:The clinical significance of the surgical resection of metastatic lymph nodes (LN) from patients with hepatocellular carcinoma (HCC) remains controversial. The aim of this study was to evaluate the significance of the surgical resection of LN metastasis of HCC. METHODS:Among 961 patients who underwent surgical...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-014-1028-8

    authors: Tomimaru Y,Wada H,Eguchi H,Tomokuni A,Hama N,Kawamoto K,Marubashi S,Umeshita K,Doki Y,Mori M,Wakasa K,Nagano H

    更新日期:2015-09-01 00:00:00

  • Surgical removal of a denture with sharp clasps impacted in the cervicothoracic esophagus: report of three cases.

    abstract::We report three cases of successful surgical removal of a denture with sharp clasps impacted in the cervical esophagus. Patient 1 was a 57-year-old woman institutionalized for over 30 years for schizophrenia, patient 2 was a 62-year-old man hospitalized for brain paralysis, and patient 3 was a 64-year-old man sufferin...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-010-4467-x

    authors: Toshima T,Morita M,Sadanaga N,Yoshida R,Yoshinaga K,Saeki H,Kakeji Y,Maehara Y

    更新日期:2011-09-01 00:00:00

  • Reconstructive surgery for a fusiform common celiomesenteric trunk aneurysm and coexistent abdominal aortic aneurysm: report of a case.

    abstract::A celiomesenteric trunk (CMT) accounts for fewer than 1% of all visceral artery anomalies. Aneurysms involving a CMT are exceptionally rare: our search of the literature found only eight cases reported. We treated a 73-year-old man with both a fusiform CMT aneurysm and an abdominal aortic aneurysm (AAA). The celiac ar...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3784-9

    authors: Obara H,Matsumoto K,Fujimura N,Ono S,Hattori T,Kitagawa Y

    更新日期:2009-01-01 00:00:00

  • CYP3A4 expression to predict treatment response to docetaxel for metastasis and recurrence of primary breast cancer.

    abstract:PURPOSE:Tumors expressing high levels of CYP3A4 are likely to have a poor treatment response to docetaxel (DOC), which is metabolized by CYP3A4. Tissue samples of recurrent breast cancer are sometimes hard to obtain just before treatment because the tumor is often difficult to access. Using immunohistochemistry, we mea...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-009-4328-7

    authors: Sakurai K,Enomoto K,Matsuo S,Amano S,Shiono M

    更新日期:2011-05-01 00:00:00

  • Effects of experimental chemoendocrine therapy with a combination of a pure antiestrogen and 5-fluorouracil on human breast cancer cells implanted in nude mice.

    abstract::The antitumor effects of an experimental chemoendocrine therapy combining a new pure antiestrogen ICI 182780 and 5-fluorouracil (5-FU) were studied on MCF-7 human breast cancer cells implanted in nude mice. ICI 182780 had a dose-dependent antitumor activity, which was potentiated by the concomitant use of 5-FU. When c...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02482240

    authors: Ogasawara Y,Doihara H,Shiroma K,Kanaya Y,Shimizu N

    更新日期:1999-01-01 00:00:00

  • Malignant mesothelioma of the tunica vaginalis testis: report of a case.

    abstract::We describe herein the case of a 68-year-old man with malignant mesothelioma of the tunica vaginalis testis. The pathological diagnosis was based upon the clinical findings, gross and microscopic morphology, and special stains. Malignant mesothelioma is a rare tumor associated with asbestos exposure that can be effect...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s005950050654

    authors: Kanazawa S,Nagae T,Fujiwara T,Fujiki R,Mukai N,Sugihara Y,Yamaguchi N,Ohtani H,Higami Y,Ikeda T,Tsunoda T

    更新日期:1999-01-01 00:00:00

  • Endovascular treatment of an aortobronchial fistula caused by a distal aortic arch mycotic aneurysm: report of a case.

    abstract::We report a case of an aortobronchial fistula causing massive hemoptysis, which was managed by emergency stent grafting. Although this procedure was successful initially, the aortobronchial fistula appeared again 7 months later. Aneurysmectomy, followed by rifampicin-soaked gelatin sealed polyester graft replacement a...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3997-y

    authors: Daitoku K,Fukuda I,Taniguchi S,Minakawa M

    更新日期:2010-01-01 00:00:00

  • Thymic papillo-tubular adenocarcinoma containing a cyst: report of a case.

    abstract::We report a case of thymic papillo-tubular adenocarcinoma in a 55-year-old man, who had no symptoms. Sternotomy revealed a tumor in the anterior mediastinum, tightly adhered to the pericardium. It was resected completely. Interestingly, the tumor contained a unilocular cyst filled with mucinous fluid, suggesting that ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-012-0161-5

    authors: Teramoto K,Kawaguchi Y,Hori T,Ishida M,Hashimoto M,Kitamura S,Motoishi M,Hanaoka J,Tezuka N,Okabe H

    更新日期:2012-10-01 00:00:00

  • Successful graft replacement of the descending aorta after an extended reconstruction of the ascending and transverse aorta in a patient with Marfan's syndrome.

    abstract::A 27-year-old man with Marfan's syndrome underwent a total aortic graft replacement in three separate stages. Initially the abdominal aorta was replaced, followed by the ascending aorta and aortic arch, and finally the residual portion. The extensive reconstruction of both the ascending and transverse aorta at the sec...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950050262

    authors: Konishi H,Ohshima K,Saitoh T,Kamisawa O,Ohki S,Hasegawa N,Kawashima T,Misawa Y,Katoh M,Fuse K

    更新日期:1998-01-01 00:00:00

  • Gastric perforation caused by a bulimic attack in an anorexia nervosa patient: report of a case.

    abstract::We report a rare case of gastric perforation due to a bulimic attack in a 17-year-old girl suffering from anorexia nervosa. She was admitted to our hospital with the chief complaint of abdominal pain following bulimia. Initially, her symptoms were reduced after drainage using a nasogastric tube. Eight hours later, how...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s005950050618

    authors: Nakao A,Isozaki H,Iwagaki H,Kanagawa T,Takakura N,Tanaka N

    更新日期:2000-01-01 00:00:00

  • Clinical characteristics of 12 cases of appendiceal diverticulitis: a comparison with 378 cases of acute appendicitis.

    abstract:PURPOSE:Previous authors have suggested that a diverticulum of the vermiform appendix has a higher risk of perforation than acute appendicitis. Therefore, this study compared appendiceal diverticulitis with acute appendicitis to explain the characteristics of appendiceal diverticulitis. METHODS:Data for this study cam...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-012-0152-6

    authors: Yamana I,Kawamoto S,Inada K,Nagao S,Yoshida T,Yamashita Y

    更新日期:2012-04-01 00:00:00

  • Jejunal cancer detected after a resection of bilateral ovarian metastasis: report of a case.

    abstract::A 50-year-old woman was admitted to our hospital because of abdominal distension and fullness. Computed tomography and magnetic resonance imaging showed bilateral ovarian tumors. Although these ovarian tumors were suspected of being metastatic, the primary tumor site could not be detected before the bilateral salpingo...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-009-4174-7

    authors: Maekawa H,Sato K,Komatsu Y,Orita H,Sakurada M

    更新日期:2010-11-01 00:00:00

  • Role of age as a prognostic factor in breast cancer.

    abstract::The effect of age on the prognosis of breast cancer remains controversial. To investigate the role of age, we reviewed 316 patients with stage I or II breast cancer. There were 14 patients below 34, 146 between 35 and 49, 115 between 50 and 65, and 41 over 66 years of age. No correlations were observed between age and...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00941647

    authors: Tsuchiya A,Abe R,Kanno M,Ohtake T,Fukushima T,Nomizu T,Kimijima I

    更新日期:1997-01-01 00:00:00

  • Thyroidectomy with LigaSure.

    abstract:PURPOSE:A new method for ensuring hemostasis during thyroid surgery has recently been introduced. This technique, electrothermal (LigaSure) and ultrasound blood vessel sealing, is still experimental. The aim of the present study was to evaluate the applications and efficacy of LigaSure by analyzing the duration of the ...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s00595-010-4364-3

    authors: Ignjatović M,Kostić Z

    更新日期:2011-06-01 00:00:00

  • Immunohistochemical distribution of bombesin-positive pulmonary neuroendocrine cells in a congenital diaphragmatic hernia.

    abstract::Morphometrical analyses of the immunohistochemical expression of bombesin, which is one of the peptides produced by pulmonary neuroendocrine (PNE) cells, were carried out on the bronchioles of human congenital diaphragmatic hernia (CDH) neonates, and the findings were then compared with those in a gestational and post...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02483031

    authors: Asabe K,Tsuji K,Handa N,Kajiwara M,Suita S

    更新日期:1999-01-01 00:00:00

  • Emergent laparoscopic cholecystectomy for acute acalculous cholecystitis revisited.

    abstract:PURPOSE:To compare the safety of emergent laparoscopic cholecystectomy for acute acalculous cholecystitis (AAC) with surgery for acute calculous cholecystitis (ACC). METHODS:We retrospectively reviewed the perioperative records of 111 patients who underwent emergent laparoscopic cholecystectomy for acute cholecystitis...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-015-1173-8

    authors: Ueno D,Nakashima H,Higashida M,Yoshida K,Hino K,Irei I,Moriya T,Matsumoto H,Hirai T,Nakamura M

    更新日期:2016-03-01 00:00:00

  • The enhanced therapeutic efficacy of intra-arterial cis-diamminedichloroplatinum (II) chemotherapy in combination with aortic clamping on metastatic hepatic tumors in the rat.

    abstract::The efficacy of intrahepatic cis-diamminedichloroplatinum (II), cisplatin, administered via the hepatic artery in combination with concomitant clamping of the abdominal aorta beneath the diaphragm against metastatic liver tumors in rats was evaluated. When 2.5 or 5 mg/kg of cisplatin was injected intra-arterially (i.a...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02473393

    authors: Nishioka Y

    更新日期:1994-01-01 00:00:00

  • Primary axillary venous aneurysm: report of a case.

    abstract::We report a case of nontraumatic, spontaneous venous aneurysm of the left axillary vein. This case may represent only the second such case ever reported in the English-language medical literature. Venous aneurysms are often associated with trauma, arteriovenous fistula, or other venous abnormal hemodynamic conditions,...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-004-2957-4

    authors: Ko PJ,Chu JJ,Lin PJ,Liu YH

    更新日期:2005-01-01 00:00:00

  • Demonstration of microcystic disease of the pancreas by magnetic resonance cholangiopancreatography: report of a case.

    abstract::A case of microcystic disease of the pancreas which was clearly demonstrated by magnetic resonance cholangiopancreatography (MRCP) is reported herein. Cystic dilatation of the pancreatic duct was recognized by computed tomography scanning and endoscopic retrograde cholangiopancreatography (ERCP). Furthermore, the exis...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02482816

    authors: Kitagawa T,Matsumoto K,Iriyama K

    更新日期:1998-01-01 00:00:00

  • Modified double-stapling technique in low anterior resection for lower rectal carcinoma.

    abstract:PURPOSE:The original double-stapling technique (DST) using a standard linear stapler horizontally can be difficult in patients with a narrow pelvis or an ultralow anastomosis. We review our experience of performing a modified DST (IO-DST) with vertical division of the rectum achieved using an endostapler. METHODS:We r...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00595-005-3088-2

    authors: Sato H,Maeda K,Hanai T,Matsumoto M,Aoyama H,Matsuoka H

    更新日期:2006-01-01 00:00:00

  • Effects of the dihydrolipoyl histidinate zinc complex against carbon tetrachloride-induced hepatic fibrosis in rats.

    abstract:PURPOSE:This study investigated the effects of an antioxidant, dihydrolipoyl histidinate zinc complex (DHLHZn), on the hepatic fibrosis in the carbon tetrachloride (CCl4) rat model. METHODS:The animals were divided into three groups: control, CCl4, and CCl4+DHLHZn. A histological assessment of the liver fibrosis was p...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-013-0749-4

    authors: Kawano Y,Ohta M,Iwashita Y,Komori Y,Inomata M,Kitano S

    更新日期:2014-09-01 00:00:00

  • Chronology of gastrointestinal cancer.

    abstract::The "chronology of cancer" is a concept that describes the nature of cancers through the measure of time. The field extends from carcinogenesis to development, progression, and metastasis. Carcinogenesis is a multi-step process, which results from the accumulation of multiple genetic or epigenetic alterations. Various...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-017-1574-y

    authors: Murakami K,Matsubara H

    更新日期:2018-04-01 00:00:00

  • Clinical significance of an increased red blood cell distribution width in patients with rectal cancer undergoing chemoradiotherapy followed by surgery.

    abstract:PURPOSE:The clinical significance of the red blood cell distribution width (RDW) in patients with rectal cancer undergoing preoperative chemoradiotherapy (CRT) followed by surgery has not been fully evaluated. METHODS:In this retrospective study, we investigated the association between the RDW and the prognosis in 120...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-019-01933-3

    authors: Ide S,Toiyama Y,Okugawa Y,Omura Y,Kitajima T,Fujikawa H,Hiro J,Ohi M,Kusunoki M

    更新日期:2020-06-01 00:00:00

  • Acinar cell carcinoma arising from an ectopic pancreas.

    abstract::We herein report a rare case of ectopic pancreatic acinar cell carcinoma (ACC) which presented as a submucosal tumor of the pylorus. A 73-year-old man came to our hospital presenting with epigastralgia. Esophago-gastroduodenal endoscopy showed no mucosal lesions, but a submucosal tumor was observed around the pylorus....

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3384-5

    authors: Mizuno Y,Sumi Y,Nachi S,Ito Y,Marui T,Saji S,Matsutomo H

    更新日期:2007-01-01 00:00:00

  • Effectiveness of scheduled intravenous acetaminophen in the postoperative pain management of video-assisted thoracic surgery.

    abstract:PURPOSE:The scheduled administration of intravenous acetaminophen (scheduled-IV-AcA) is one of the more effective multimodal analgesic approaches for postoperative pain in abdominal/orthopedic surgeries. However, there is little evidence concerning scheduled-IV-AcA after general thoracic surgery, especially when limite...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-020-02127-y

    authors: Shikatani Y,Soh J,Shien K,Kurosaki T,Ohtani S,Yamamoto H,Taniguchi A,Okazaki M,Sugimoto S,Yamane M,Oto T,Morimatsu H,Toyooka S

    更新日期:2020-09-02 00:00:00

  • Surgical treatment for chronic pleural empyema.

    abstract::Various surgical procedures have been developed in an attempt to alleviate the significant problems caused by chronic pleural empyema. The present study evaluates our 11-year experience of employing a number of therapeutic approaches for chronic empyema. Between 1987 and 1997, 45 consecutive patients underwent treatme...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950070116

    authors: Okada M,Tsubota N,Yoshimura M,Miyamoto Y,Yamagishi H,Satake S

    更新日期:2000-01-01 00:00:00

  • Cor triatriatum sinistrum: surgical experience in Taiwan.

    abstract:PURPOSE:Cor triatriatum sinister, more commonly referred to as cor triatriatum (CT), is characterized by a common pulmonary venous chamber (proximal chamber) separated from the left atrium (distal chamber) by a fibromuscular septum. This report of our experience updates the surgical results of this anomaly in the Asian...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3341-3

    authors: Huang YK,Chu JJ,Chang JP,Lu MS,Tseng CN,Chang YS,Tsai FC,Lin PJ

    更新日期:2007-01-01 00:00:00