Abstract:
BACKGROUND:MicroRNAs (miRs) are involved in gene expression and function, but little is known of their function in ischemia-reperfusion injury (IRI), which plays a critical role in flap compromise during microvascular flap surgeries. This article aimed to determine the expression profiles of miRs in rat flap surgeries after IRI. METHODS:Vessel specimens in rat epigastric flap were initially determined for miRs survey after 2 hours of ischemia and 2 hours of reperfusion. Their miR expressions were further quantified after 2 hours of ischemia and subsequent reperfusion for 2 and 24 hours. RESULTS:Only 3 miRs (miR-21, miR-193-3p, and miR-210) in rat vessels, but not in flap tissues, were significantly up-regulated at 24 hours of reperfusion after 2 hours of ischemia. CONCLUSIONS:Our findings provide insights into deregulated expressions of miRs in flap surgeries after IRI. They might provide a further therapeutic consideration to prevent vascular compromise due to IRI in flap surgeries.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Chang KP,Lee HC,Huang SH,Lee SS,Lai CS,Lin SDdoi
10.1097/SAP.0b013e3182742c45subject
Has Abstractpub_date
2012-12-01 00:00:00pages
668-71issue
6eissn
0148-7043issn
1536-3708pii
00000637-201212000-00016journal_volume
69pub_type
杂志文章abstract::We report 2 patients with paraspinous sarcoma treated with omental transposition tunneled through a defect in the lumbar fascia that resurfaced in the soft tissues of the lower back. Traditional reconstruction with skin flaps was unsatisfactory because of prior irradiation to the area. In 1 patient the omentum obliter...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199312000-00015
更新日期:1993-12-01 00:00:00
abstract::The gastrocnemius muscle flap has gained wide acceptance as a reconstructive technique for management of wounds of the knee and proximal tibia. The use of the muscle as a pedicle flap to the distal and middle femur has not been well quantified, and the proximal rotation arc has been underestimated. We report the use o...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199504000-00014
更新日期:1995-04-01 00:00:00
abstract:PURPOSE:This study aims to understand the degree to which ptosis is recognizable to a layperson. METHODS:Fifteen color drawings of a gender-neutral human face were created. Six faces exhibited right-sided ptosis (decreased margin reflex distance 1 and lengthened tarsal platform show) of 0.5 mm, 1 mm, 1.5 mm, 2 mm, 2.5...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001524
更新日期:2018-09-01 00:00:00
abstract::Early complications following aortofemoral bypass grafting include acute limb ischemia, renal failure, bowel and spinal cord ischemia, and myocardial infarction. Although the literature recognizes these more common complications, we have found very few reports that raised the possibility of an anatomically determined,...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199612000-00014
更新日期:1996-12-01 00:00:00
abstract:INTRODUCTION:Implantation rates of cardiac implantable electrophysiological devices (CIEDs) are rising, mainly because of the expansion of implantable cardioverter-defibrillators indications for primary prevention. As the CIED usage increases, CIED-related complications are also in rise. Transvenous approach and laser ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001985
更新日期:2020-01-01 00:00:00
abstract::Chronic stasis ulcers of the lower extremity can prove difficult to treat. In the event that conservative treatment fails, one approach is to excise the ulcer, ligate the incompetent perforating veins, and close the defect by muscle transposition, followed by application of skin grafts to the transposed muscles. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-197901000-00009
更新日期:1979-01-01 00:00:00
abstract::Oronasal fistula formation is a recalcitrant complication following palatoplasty, resulting in nasal emission during speech and deglutition. We review our series to identify factors associated with fistula incidence. A retrospective review of all children with nonsyndromic cleft palate who underwent 2-flap palatoplast...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318199669b
更新日期:2009-12-01 00:00:00
abstract::Since 1993, a total of 41 free osteofasciocutaneous fibular flaps with an extended skin island (average dimensions, 16.9 cm long [range, 12-22 cm] x 10.7 cm wide [range, -16 cm], or 180.8 cm [range, 112-352 cm ]) have been used in by the authors in various clinical applications. To evaluate donor site morbidity, the 4...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200208000-00005
更新日期:2002-08-01 00:00:00
abstract::Traditional gastrocnemius flap harvest requires a long skin incision, starting from the popliteal fossa to the mid leg. The authors designed three instruments to facilitate harvest of this flap through a small incision without the help of an endoscope in 10 patients. All 10 gastrocnemius muscle flaps survived with a 1...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200108000-00005
更新日期:2001-08-01 00:00:00
abstract::Although most commonly seen with dental extractions, inferior alveolar nerve injury is occasionally seen with orthognathic surgery and facial trauma. Nerve grafting can be performed by lateral corticotomy without the use of maxillomandibular fixation. A case is reported with this technique and recovery of sensibility ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199408000-00019
更新日期:1994-08-01 00:00:00
abstract::Exposure of silicone breast implants usually leads to infection and extrusion. According to the literature, implant extrusion rates are not higher than 2% 1 and removal of the implant is recommended. 2 During the past 3 years, the authors dealt with eight implant exposures (six women: two cases of bilateral exposure a...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.SAP.0000044251.40733.2B
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:This study of stage III (locally advanced) breast cancer patients evaluated the survival improvement conferred by immediate breast reconstruction by transverse rectus abdominis musculocutaneous (TRAM) flap reconstruction after modified radical mastectomy (MRM) in comparison with MRM alone. METHODS:This retr...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000251
更新日期:2014-09-01 00:00:00
abstract::A case of delayed infection following the use of split-cranial bone graft is presented. Trauma and bacterial contamination of the donor area six months before harvest were the likely causes. We advise caution and the use of alternate donor sites in cases where a history of previous contaminating trauma exists, even if...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199003000-00014
更新日期:1990-03-01 00:00:00
abstract::The purpose of this study was to investigate the efficacy of cilostazol for prevention of thrombosis in microsurgical anastomosis. We used not only a patency test, but also ultrasonography to evaluate the blood flow volume (FV) more accurately and objectivity. In addition, we evaluated the accuracy and sensitivity of ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31819aad6c
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:The recent rise in medical tourism, especially for cosmetic procedures, has been mirrored by an increase in the incidence of infections with Mycobacterium abscessus, which is an atypical mycobacterium that is ubiquitous in aquatic environments. M. abscessus soft tissue infections arise from the use of improp...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002061
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:We had reported the surgical outcome of reverse skin redraping technique for restoration of previously performed epicanthoplasty. In this study, we introduce a modified reverse skin redraping technique that added mini-epicanthoplasty in patients with unsatisfactory results after epicanthoplasty. METHODS:Three ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000991
更新日期:2017-06-01 00:00:00
abstract::The objective of this study was to assess the accuracy of magnetic resonance imaging (MRI) in detecting silicone breast implant rupture, and to explore implications of the use of MRI for screening and estimating the prevalence of rupture among asymptomatic women. The study consisted of a meta-analysis of published stu...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,meta分析
doi:10.1097/00000637-200110000-00002
更新日期:2001-10-01 00:00:00
abstract:INTRODUCTION:Pyoderma gangrenosum following free tissue transfer for breast reconstruction is rare. This unusual ulcerative condition is frequently misdiagnosed, leading to inappropriate debridement and escalation of the subsequent wound through pathergy. Once diagnosed, treatment with immunosuppressive agents, includi...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001782
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Placement of suction drainage in submuscular pockets is routinely performed in breast reconstruction. Days of drain permanence (DDP) are associated with hospital stay and related health care costs. The aims of this study are to retrospectively compare data related to DDP and total drainage volume between hig...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001246
更新日期:2018-04-01 00:00:00
abstract::Mastectomy has traditionally been performed using a transverse elliptical incision. The disadvantages of this approach are a potentially visible scar medially and poor subincisional soft-tissue coverage of implants laterally. A more natural and aesthetic result is obtained with an oblique incision running parallel to ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000119
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Current approaches for the treatment of gingival exposure are often time- and cost-consuming and/or rather invasive. We previously observed a strong correlation between the presence of gingival excess and midfacial depression and here propose an easy 1-step correction technique as a new strategy to improve g...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000735
更新日期:2016-12-01 00:00:00
abstract::During the past 10 years, there have been extensive developments in both "island" muscle and musculocutaneous flaps and in "free" microvascular transfers. Competition still exists between these two schools of surgical methodology, even though both methods are known to be complementary and have comparable success rates...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-198710000-00012
更新日期:1987-10-01 00:00:00
abstract::A bayonet-shaped airway allowing free respiration and undisturbed deglutition was reconstructed in 2 young women who had undergone tracheotomy and radiotherapy for thyroid carcinoma. The laryngeal vestibule, glottis, and subglottis had been destroyed, and the air passages were closed. An external gutter and an anterio...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198605000-00010
更新日期:1986-05-01 00:00:00
abstract::Aggressive thinning of the muscle from the pedicle of a gastrocnemius musculocutaneous flap can change the nature of that pedicle radically. Instead of being bulky and causing contour deformity, the pedicle is reduced to a vascular leash that has virtually no effect on contour at all. Radical thinning of this type was...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198910000-00018
更新日期:1989-10-01 00:00:00
abstract::Recurrent cicatricial entropion of the upper eyelid creates a surgical problem. We present a 53-year-old patient with complicated postsurgical fibrotic and scarred upper eyelid entropion. Double-opposed Z-plasty incisions were used at the anterior approach. The outer Z incision included the skin and the orbicularis oc...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199309000-00013
更新日期:1993-09-01 00:00:00
abstract:INTRODUCTION:The traditions of surgical education have changed little over the years. However, the increasing focus on patient safety and duty hour restrictions mandates that residents start developing complex skill sets earlier to ensure they graduate with procedural competency. Surgical training is poised to exploit ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002265
更新日期:2021-02-01 00:00:00
abstract::A study of the psychological aspects of mastectomy and reconstruction was carried out. A review of the literature revealed varied emotional responses to the mastectomy experience. An initial, limited study was designed to investigate the attitudes of two groups of women, one that chose reconstruction after mastectomy ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198407000-00008
更新日期:1984-07-01 00:00:00
abstract::Double-breasted closure of the skin is achieved by deepithelialization of 1 edge of a wound and advancement of the opposite edge over this deepithelialized area. Such closure may prevent contamination or exposure of the implant in cases where immediate breast reconstruction with prosthetic material is obtained after s...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000174362.35948.65
更新日期:2005-09-01 00:00:00
abstract::In the literature, few studies based on clinical and histological evaluation analyze skin structural changes after transplantation to the oral cavity. Ten patients affected by squamous cell carcinoma of the oral cavity who were reconstructed with a free forearm flap were included in the current study to analyze skin a...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200210000-00005
更新日期:2002-10-01 00:00:00
abstract::Over the past century, many advancements have been made in peripheral nerve repair, yet these reconstructions still remain a challenge. Although sutures have historically been used for neurorrhaphy, they sometimes fail to provide optimal outcomes. As a result, multiple adhesive compounds are currently being investigat...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002408
更新日期:2021-01-01 00:00:00