Abstract：
:Reductions in flicker sensitivity in ocular hypertension are thought to precede manifest glaucomatous damage, but the proportion of patients with ocular hypertension reported to have losses in flicker sensitivity (50-90%) is far out of step with the proportion of ocular hypertensive patients in whom clinically defined glaucoma will develop (5-30%). The authors examined the possibility that the flicker losses in some of these patients represent not early glaucomatous damage, but instead a transient influence of raised intraocular pressure (IOP) on an otherwise normal eye. Temporal contrast sensitivity was measured in 26 patients with ocular hypertension and in 22 patients with primary open-angle glaucoma (POAG) before and after hypotensive treatment (timolol). Compared with normotensive controls, all POAG patients exhibited sensitivity losses before treatment which remained unchanged after treatment. The ocular hypertensive patients were divided into three groups, which may reflect differing risks of glaucoma conversion. Group I patients (8/26) had normal flicker sensitivity, and thus appear to be resistant to high IOP. Group II patients (9/26) showed initial losses which disappeared with lowered IOP. They probably have not yet suffered damage but appear to be sensitive to high IOP. Group III patients (9/26) had losses that persisted despite lowered IOPs. The similarity of their response to that of the POAGs suggests that group III patients have already suffered early glaucomatous damage.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Tytla ME,Trope GE,Buncic JRdoi
10.1016/s0161-6420(90)32630-1subject
Has Abstractpub_date
1990-01-01 00:00:00pages
36-43issue
1eissn
0161-6420issn
1549-4713pii
S0161-6420(90)32630-1journal_volume
97pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract：OBJECTIVE:To determine the outcome of pediatric dacryocystorhinostomy (DCR) for large mucoceles or for primary nasolacrimal duct obstruction unresponsive to multiple probings. DESIGN:Retrospective noncomparative case series. PARTICIPANTS:One hundred thirty-four external dacryocystorhinostomies were performed in 121 c...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(01)00699-6
更新日期：2001-09-01 00:00:00
abstract：OBJECTIVE:To describe the initial experience and to evaluate the safety and feasibility of using the 25-gauge Transconjunctival Sutureless Vitrectomy System (TSV) for a variety of vitreoretinal procedures. DESIGN:Retrospective review of a consecutive interventional case series. PARTICIPANTS:Thirty-five eyes of 33 pat...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(02)01119-3
更新日期：2002-10-01 00:00:00
abstract：:Ophthalmologists continue to share in the professional liability claims that plague the medical profession. Data have been extrapolated from the April 1987 publication of the United States General Accounting Office (GAO) entitled, "Medical Malpractice Characteristics of Claims Closed in 1984." This document presents i...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(90)32407-7
更新日期：1990-10-01 00:00:00
abstract：PURPOSE:To describe a systematic approach for managing the structural adnexal anomalies encountered in Fraser syndrome, a multisystem, autosomal recessive condition associated with cryptophthalmos. DESIGN:Retrospective, noncomparative, interventional case series. PARTICIPANTS:All patients with Fraser syndrome-related...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2009.05.018
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:To describe clinical characteristics, management, and complications of primary iris stromal cysts. DESIGN:A retrospective review. RESULTS:Seventeen consecutive patients with primary iris stromal cysts were found. Nine (52%) patients were diagnosed under age 10 years (range, 1 day-7 years), and eight (47%) p...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/S0161-6420(98)97041-5
更新日期：1998-07-01 00:00:00
abstract：BACKGROUND:Opportunistic infections frequently involve the anterior and posterior segments of the eye but rarely occur in the orbit in patients with human immunodeficiency virus (HIV) infection. The authors managed eight patients with HIV and unilateral orbital infections who presented between July 1988 and March 1995....
journal_title：Ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0161-6420(96)30479-x
更新日期：1996-09-01 00:00:00
abstract：PURPOSE:Indocyanine green (ICG) angiography may improve visualization of choroidal neovascularization (CNV) associated with serous retinal pigment epithelial detachment (RPED) in age-related macular degeneration (AMD). The features of ICG hyperfluorescence associated with serous RPED and therapeutic effect of ICG-direc...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(97)30236-x
更新日期：1997-05-01 00:00:00
abstract：:The Diabetic Retinopathy Study (DRS) demonstrated that prompt argon laser photocoagulation, in comparison to indefinite delay in treatment, could reduce by more than 50% the risk of severe visual loss from proliferative diabetic retinopathy. The DRS also enlightened two generations of ophthalmologists about the value ...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/s0161-6420(87)33523-7
更新日期：1987-07-01 00:00:00
abstract：:Superior sulcus deformity is a late sequela of surgical anophthalmos. Many methods have been proposed to treat this difficult problem. A technique using autogenous costal cartilage that has resulted in satisfactory repair is presented. In addition to standard photographs and exophthalmometry measurements to follow the...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(82)34772-7
更新日期：1982-05-01 00:00:00
abstract：PURPOSE:To compare the timing, radiologic, and clinical indications for surgical management of orbital floor fractures in the pediatric and adult populations. DESIGN:Retrospective observational case series. PARTICIPANTS:Twenty-four pediatric and 31 adult patients who underwent primary repair of an orbital floor fract...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2008.02.025
更新日期：2008-09-01 00:00:00
abstract：PURPOSE:To describe the association of demographic, behavioral, medical, and nonretinal ocular factors with the incidence of neovascular age-related macular degeneration (AMD) and central geographic atrophy (CGA) in the Age-Related Eye Disease Study (AREDS), a randomized trial of antioxidants and zinc supplementation p...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ophtha.2004.10.047
更新日期：2005-04-01 00:00:00
abstract：:The present paper documents the clinical characteristics and ocular pathology in a patient with abetalipoproteinemia. Noteworthy were: the predominant involvement of the posterior fundus characterized by a loss of photoreceptors; loss or attenuation of the pigment epithelium (producing a sharply demarcated white appea...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(84)34203-8
更新日期：1984-08-01 00:00:00
abstract：PURPOSE:To study the associations between long-term and short-term use of topical beta-blockers and mortality. DESIGN:Prospective population-based cohort study. PARTICIPANTS:To examine long-term effects, 3842 participants aged 55 years and older were recruited. To examine short-term effects, 484 incident beta-blocker...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2008.07.004
更新日期：2008-11-01 00:00:00
abstract：PURPOSE:To examine the clinical features of undiagnosed open-angle glaucoma (OAG) in people who have attended an eye care provider within the previous 12 months and to suggest strategies to assist in the early detection of glaucoma. DESIGN:Population based cross-sectional study. PARTICIPANTS:Permanent residents aged ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2004.01.029
更新日期：2004-08-01 00:00:00
abstract：:Normal crystalline lenses and a variety of primary and secondary cataracts were photographed with a contact clinical specular microscope having a new W10X long working distance objective. In the normal lens, the anterior and posterior cell pattern and the lens fiber pattern could be seen. In patients with developing c...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(83)34548-6
更新日期：1983-04-01 00:00:00
abstract：:The authors analyzed the clinical and follow-up data on 277 selected patients with primary choroidal or ciliochoroidal melanoma who were treated with 60Co plaque radiotherapy between 1976 and 1982. Local recurrence of the irradiated melanoma developed in 39 (14%) patients during the follow-up interval. The 5-year tumo...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(89)32882-x
更新日期：1989-03-01 00:00:00
abstract：:Glaucoma after pediatric cataract surgery, once well recognized, now occurs only rarely after modern lensectomy/vitrectomy. The authors performed directed glaucoma evaluations of 34 eyes of 26 children. Based on intraocular pressures of 26 mmHg or greater, glaucoma was diagnosed in 8 (24%) eyes of 7 (27%) children. Gl...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(91)32235-8
更新日期：1991-05-01 00:00:00
abstract：OBJECTIVE:This study aimed to investigate the age-related changes in the position of zonular insertion onto the anterior lens capsule. DESIGN:The study design was an experimental cadaveric eye study. PARTICIPANTS:Two hundred twenty-three cadaveric eyes (range, 16-100 years old) from eye banks in the United States wer...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(98)93172-4
更新日期：1998-02-01 00:00:00
abstract：:In 2019, the American Academy of Ophthalmology (AAO) created the Task Force on Myopia in recognition of the substantial global increases in myopia prevalence and its associated complications. The Task Force, led by Richard L. Abbott, MD, and Donald Tan, MD, comprised recognized experts in myopia prevention and treatme...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2020.10.040
更新日期：2020-12-30 00:00:00
abstract：PURPOSE:To analyze the visual outcome, systemic associations, effectiveness of treatment, and predicting features of 104 scleritis patients. DESIGN:Retrospective case series. PARTICIPANTS:One hundred four patients treated for scleritis at the University Medical Centers of Groningen and Utrecht, The Netherlands. METH...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2012.08.005
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To examine the safety and efficacy of anterior ciliary sclerotomy to restore accommodation in the presbyopic eye. DESIGN:Prospective nonrandomized comparative single-center clinical trial. PARTICIPANTS:Nine presbyopic subjects with no prior ocular surgery except corneal refractive procedures were enrolled. M...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/s0161-6420(02)01252-6
更新日期：2002-11-01 00:00:00
abstract：PURPOSE:To use optical coherence tomography (OCT) to evaluate the femtosecond laser intrastromal incisions made during cataract surgery to reduce corneal astigmatism. DESIGN:Retrospective case series. PARTICIPANTS:Seventy-seven eyes of 77 patients. METHODS:Paired intrastromal incisions were created using the Catalys...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2017.03.022
更新日期：2017-08-01 00:00:00
abstract：:The authors examined the relationship of change in tumor height after proton beam irradiation with the risk of metastasis in 700 patients treated for uveal melanoma before July 1, 1986. Rates of change in tumor height were computed for each patient using follow-up ultrasonographic measures during the first 2 years aft...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(89)32685-6
更新日期：1989-10-01 00:00:00
abstract：OBJECTIVE:To report the long-term efficacy and safety of the interleukin-6 receptor antagonist tocilizumab for refractory uveitis-related macular edema (ME). DESIGN:Retrospective cohort study. PARTICIPANTS:Eyes with uveitis seen at a single tertiary referral center for which ME was the principal cause of reduced visu...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2014.06.050
更新日期：2014-12-01 00:00:00
abstract：:A 13-year-old boy presented with a 2-month history of swelling of the right upper eyelid and displacement of the right eye. Computed tomography (CT) showed a tumor in the right orbit and a large osteolytic defect of the orbital frontal bone. At surgery a yellowish-tan mass was found replacing the orbital roof and abut...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(87)33352-4
更新日期：1987-08-01 00:00:00
abstract：PURPOSE:To describe a newly recognized clinical syndrome consisting of ptosis, diplopia, vertical gaze limitation, and abduction weakness that can occur after orbital roof removal during orbito-zygomatic-pterional craniotomy. DESIGN:Case series. PARTICIPANTS:Eight study patients (7 women), 44 to 80 years of age, with...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2014.09.011
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:Geographic atrophy (GA) may cause significant compromise of visual function, even when there still is good visual acuity (VA), because of parafoveal scotomas and foveal function abnormalities antedating visible atrophy. This study evaluates the visual function abnormalities at baseline and the 2-year worsening ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(97)30079-7
更新日期：1997-10-01 00:00:00
abstract：:Three patients with idiopathic central serous chorioretinopathy (ICSC) and bullous retinal detachment (RD) were examined at least 2 years after the onset of the disease in one patient and over 10 years in the other two patients. There were large areas of retinal pigment epithelium (RPE) degeneration in each patient. I...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(87)33243-9
更新日期：1987-12-01 00:00:00
abstract：OBJECTIVE:We developed low-concentration homogenized castor oil eye drops for the treatment of patients with noninflamed obstructive meibomian gland dysfunction (MGD), a major cause of lipid-deficiency dry eye, and assessed the safety, stability, and efficacy of the eye drops. DESIGN:Randomized, double-masked, placebo...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0161-6420(02)01262-9
更新日期：2002-11-01 00:00:00
abstract：:Arteriohepatic dysplasia (AHD, Alagille's syndrome) is presumed to be one of the six known familial intrahepatic cholestatic syndromes, all of which present with neonatal jaundice or failure to thrive, or both. Accurate early diagnosis of the proper syndrome is important, as arteriohepatic dysplasia has a good prognos...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(81)35026-x
更新日期：1981-04-01 00:00:00
