Abstract：
OBJECTIVE:To evaluate in a preliminary manner the feasibility, safety, and efficacy of Constraint-Induced Movement therapy (CIMT) of persons with impaired lower extremity use from multiple sclerosis (MS). DESIGN:Clinical trial with periodic follow-up for up to 4 years. SETTING:University-based rehabilitation research laboratory. PARTICIPANTS:A referred sample of ambulatory adults with chronic MS (N=4) with at least moderate loss of lower extremity use (average item score ≤6.5/10 on the functional performance measure of the Lower Extremity Motor Activity Log [LE-MAL]). INTERVENTIONS:CIMT was administered for 52.5 hours over 3 consecutive weeks (15 consecutive weekdays) to each patient. MAIN OUTCOME MEASURES:The primary outcome was the LE-MAL score at posttreatment. Secondary outcomes were posttreatment scores on laboratory assessments of maximal lower extremity movement ability. RESULTS:All the patients improved substantially at posttreatment on the LE-MAL, with smaller improvements on the laboratory motor measures. Scores on the LE-MAL continued to improve for 6 months afterward. By 1 year, patients remained on average at posttreatment levels. At 4 years, half of the patients remained above pretreatment levels. There were no adverse events, and fatigue ratings were not significantly changed by the end of treatment. CONCLUSIONS:This initial trial of lower extremity CIMT for MS indicates that the treatment can be safely administered, is well tolerated, and produces substantially improved real-world lower extremity use for as long as 4 years afterward. Further trials are needed to determine the consistency of these findings.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Mark VW,Taub E,Uswatte G,Bashir K,Cutter GR,Bryson CC,Bishop-McKay S,Bowman MHdoi
10.1016/j.apmr.2012.09.032subject
Has Abstractpub_date
2013-04-01 00:00:00pages
753-60issue
4eissn
0003-9993issn
1532-821Xpii
S0003-9993(12)01063-5journal_volume
94pub_type
临床试验,杂志文章abstract：:Positive sharp waves occur in a variety of neurogenic, myogenic, and metabolic disorders. Although not synonymous with denervation, their presence is usually associated with some type of pathology. The authors found only one reported series of patients who had diffuse insertional positive waves but no demonstrable und...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
abstract：:Symptomatic postpolio patients report improved function when they pace their activities, but this has never been objectively assessed. The purpose of this study was to determine whether seven symptomatic postpolio subjects would (1) have less evidence of local muscle fatigue and recover strength more readily when they...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：:It has been suggested that the onset of physical disability may lead to deficits in assertiveness. Therefore, in the present study assertiveness, interpersonal discomfort, anxiety, and demographic variables were investigated among lower limb amputees. Amputees completed self-report measures and hospital visitors serve...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1985-10-01 00:00:00
abstract：OBJECTIVE:To examine the association between the Medicare pressure ulcer quality indicator (the development of new or worsened pressure ulcers) and rehabilitation outcomes among Medicare patients seen in an inpatient rehabilitation facility (IRF). DESIGN:Retrospective descriptive study. SETTING:IRFs subscribed to the...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.03.007
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:To assess parent ratings of treatment acceptability associated with botulinum toxin type A (BTX-A) injection for spasticity in children with cerebral palsy (CP). DESIGN:A single-point survey design across a sequentially recruited cohort, using a standardized evaluation measure. SETTING:Regional specialty he...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2006.08.343
更新日期：2006-12-01 00:00:00
abstract：OBJECTIVE:To assess the diagnostic and clinical utility of the 2-item Generalized Anxiety Disorder Scale (GAD-2) for screening anxiety symptoms in individuals with multiple sclerosis (MS). DESIGN:Cross-sectional. SETTING:University-affiliated MS neurology and rehabilitation center. PARTICIPANTS:The sample comprised ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.05.029
更新日期：2018-10-01 00:00:00
abstract：:Cortical somatosensory evoked potential (CSEP) examinations were performed of 20 patients with lumbar spinal stenosis a day prior to surgery and 10 to 12 days after spinal decompression and bilateral lateral fusion. CSEPs were recorded to Cz-Fz (10-20 international EEG system) following stimulation of 32 tibial, peron...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:To recommend instrument assessment criteria, deriving from psychometric textbooks and articles and disability and research experts, for reviewing and assessing surveys and questionnaires for disability outcomes research. Traditional criteria are recommended, including psychometric properties of validity, reliability, ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1053/apmr.2000.20619
更新日期：2000-12-01 00:00:00
abstract：:The H-reflex has been recorded from the flexor carpi radialis muscle in the upper limb and vastus medialis (quadriceps) muscle in the lower limb in relaxed healthy subjects. The characteristics of these reflexes have been compared with those of the soleus H-reflexes, recorded with the same technique, and similar behav...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：OBJECTIVE:To investigate the physiologic differences during multispeed treadmill walking and physical activity profiles for the Otto Bock C-Walk foot (C-Walk), Flex-Foot, and solid ankle cushion heel (SACH) foot in people with transtibial amputation. DESIGN:A repeated-measures design with 3 prostheses. SETTING:Resear...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2005.07.310
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVES:To describe walking measurement in children with spina bifida and to identify patterns in the use of walking measures in this population. DATA SOURCES:Seven medical databases-Medline, PubMed, Embase, Scopus, Web of Science, CINAHL, and AMED-were searched from the earliest known record until March 11, 2014. ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1016/j.apmr.2015.04.014
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:To develop a valid and reliable spinal cord injury (SCI) specific physical functioning (PF) scale for the Veterans Health Administration (VHA) version of the 36-Item Short-Form Health Survey. DESIGN:A mixed qualitative and quantitative research design was used. In phase 1, a pool of SCI-specific PF items was...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2006.05.010
更新日期：2006-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of a replicable group treatment program to improve social communication skills after traumatic brain injury (TBI). DESIGN:Randomized treatment and deferred treatment controlled trial, with follow-up at 3, 6, and 9 months post-treatment. SETTING:Community. PARTICIPANTS:Volunteer sam...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2007.07.033
更新日期：2007-12-01 00:00:00
abstract：:Monocular patching has been advocated as a treatment for spatial neglect. Eye patching, however, is also reported to increase spatial bias. Thus, patching brain injury patients for ocular conditions may also impair their attention. To learn if an eye patch may induce asymmetric attention in a patient without spatial n...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.08.076
更新日期：2004-06-01 00:00:00
abstract：:The influence of the posterior vertebral ligamentous and bony elements on the sagittal range of motion of the lumbar spine has been investigated by observing the effects of sectioning ligaments and pedicles in 17 cadavers of both sexes with an age range from 14 to 78 years. The main investigation showed that the apoph...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1983-07-01 00:00:00
abstract：OBJECTIVES:To identify cancer patients' symptoms at admission and on discharge from an acute rehabilitation unit, to document the discharge medications used for symptom management, and to assess how symptoms affect lengths of stay (LOS). DESIGN:Retrospective chart review. SETTING:Acute inpatient rehabilitation unit w...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2007.03.032
更新日期：2007-07-01 00:00:00
abstract：:This study attempted to measure whether immediate videotape feedback would improve the degree of motor learning and ambulation performances of amputee patients. Twelve amputee patients were randomly assigned either to a control or to an experimental group. Subjects in the experimental group were videotaped during four...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1978-03-01 00:00:00
abstract：OBJECTIVE:To evaluate long-term outcomes of a noninvasive cortical stimulation technology in the treatment of fibromyalgia (FM). DESIGN:After trial follow-up survey of subjects who had completed a randomized, controlled, double-blind study of noninvasive cortical stimulation therapy some 45 months previously. SETTING...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2012.04.006
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVE:To assess the psychometric properties of a scale for spatial neglect in everyday life. DESIGN:Validation study. SETTING:A neurologic rehabilitation unit in a university hospital. PARTICIPANTS:Eighty-three consecutive right-hemisphere stroke patients. INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:Th...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1053/apmr.2003.50062
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To compare comprehensively the likelihood of various socioeconomically relevant outcomes between functional restoration completers and noncompleters, while simultaneously identifying risk factors for noncompletion. DESIGN:A prospective cohort study of patients with chronic disabling occupational musculoskele...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2005.02.010
更新日期：2005-08-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of unilateral upper-limb strength training on the finger-pinch force control of older men. DESIGN:Pretest and post-test 6-week intervention study. SETTING:Exercise science research laboratory. PARTICIPANTS:Eleven neurologically fit older men (age range, 70-80y). INTERVENTION:The ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2007.05.014
更新日期：2007-08-01 00:00:00
abstract：OBJECTIVE:To investigate differential item functioning or item bias of the Rivermead Mobility Index (RMI) and its impact on the drawing of valid comparisons with the RMI between subgroups of patients after stroke who differ with respect to age, sex, or side of lesion. DESIGN:Cross-sectional study. SETTING:A rehabilit...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2011.12.015
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVES:To describe the methods of a longitudinal cohort study among older adults with preclinical disability. The study aims to address the lack of evidence guiding mobility rehabilitation for older adults by identifying those impairments and impairment combinations that are most responsible for mobility decline an...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2012.08.217
更新日期：2013-02-01 00:00:00
abstract：UNLABELLED:This learner-directed module on spinal cord injury (SCI) presents a variety of perspectives of the process of personal and environmental adaptation for reintegration. Adaptation is unique to each person and does not predictably follow stages. Models used for understanding the process include biopsychosocial,...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1053/apmr.2002.32178
更新日期：2002-03-01 00:00:00
abstract：OBJECTIVE:To determine the effect of visual feedback on the propulsion effectiveness of experienced manual wheelchair users. DESIGN:Controlled trial. SETTING:A motion analysis laboratory. PARTICIPANTS:A convenience sample of 16 healthy men and 2 healthy women with T4-L2 traumatic paraplegia, a mean age of 38+/-9 yea...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2005.12.033
更新日期：2006-04-01 00:00:00
abstract：:The relationship between surface myoelectric signal variables and ankle joint angle is studied in the tibialis anterior muscle of ten normal subjects during electrical stimulation of the main muscle motor point in isometric conditions. Rectangular current pulses of 0.1 ms width and 20Hz repetition rate were applied fo...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(93)90114-p
更新日期：1993-05-01 00:00:00
abstract：:Personality hardiness, which has been conceptualized as a potential internal resource facilitating stress resistance, was examined in conjunction with Type A behavior, perceived family cohesion and adaptability, and sociodemographic and medical variables to assess the independent differential correlations of these fac...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：OBJECTIVE:To evaluate a personal computer (PC) gaming platform as a means of improving postural balance in stroke patients. PARTICIPANTS:Stroke patients (N=54) were enrolled and randomly divided into experimental and control groups. DESIGN:The experimental group underwent 12 weeks of rehabilitation involving playing ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2018.11.001
更新日期：2019-04-01 00:00:00
abstract：:The purpose of this study was to evaluate and compare resistance exercise training with and without pelvic stabilization on the development of isolated lumbar extension strength. Isometric torque of the isolated lumbar extensor muscles was measured at seven positions through a 72 degree range-of-motion on 47 men and 3...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：OBJECTIVE:To examine associations between organizational characteristics of home health agencies (eg, profit status, rehabilitation therapy staffing model, size, and rurality) and quality outcomes in Medicare beneficiaries with rehabilitation-sensitive conditions, conditions for which occupational, physical, and/or spe...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2017.08.483
更新日期：2018-06-01 00:00:00
