Commentary: How the debate about comparative effectiveness research should impact the future of clinical trials.

Abstract:

:Comparative effectiveness research represents the kind of research that arguably more directly affects clinical practice and policy. It includes observational studies, clinical trials, and systematic syntheses of existing literature. In this commentary, I argue for the ongoing and critical role of randomization in comparative effectiveness, noting the key differences between practical and explanatory trials.

journal_name

Stat Med

journal_title

Statistics in medicine

authors

Lauer MS

doi

10.1002/sim.5400

subject

Has Abstract

pub_date

2012-11-10 00:00:00

pages

3051-3

issue

25

eissn

0277-6715

issn

1097-0258

journal_volume

31

pub_type

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