Abstract:
BACKGROUND:The role of processed meat in the aetiology of several cancers was explored in detail. METHODS:In the time period 1996-2004, a multisite case-control study was conducted in Montevideo, Uruguay. The study included 6 060 participants (3 528 cases and 2 532 controls) corresponding to cancers of the oral cavity, pharynx, oesophagus, stomach, colon, rectum, larynx, lung, female breast, prostate, urinary bladder, and kidney (renal cell carcinoma only). RESULTS:The highest odds ratios (ORs) were positively associated with cancers of the colon, rectum, stomach, oesophagus, and lung. With the exception of renal cell carcinoma, the remaining cancer sites were significantly associated with elevated risks for processed meat consumption. Furthermore, mortadella, salami, hot dog, ham, and salted meat were strongly associated with risk of several cancer sites. CONCLUSION:It could be concluded that processed meat intake could be a powerful multiorgan carcinogen.
journal_name
Br J Cancerjournal_title
British journal of cancerauthors
De Stefani E,Boffetta P,Ronco AL,Deneo-Pellegrini H,Correa P,Acosta G,Mendilaharsu M,Luaces ME,Silva Cdoi
10.1038/bjc.2012.433subject
Has Abstractpub_date
2012-10-23 00:00:00pages
1584-8issue
9eissn
0007-0920issn
1532-1827pii
bjc2012433journal_volume
107pub_type
杂志文章,多中心研究abstract::Eighteen patients with inoperable hepatocellular carcinoma (HCC) were treated with intrahepatic arterial yttrium-90 microspheres. All these patients showed a lung shunting below 15% and a tumour-to-normal ratio higher than 2 as determined by diagnostic technetium-99m macroaggregated albumin (Tc-MAA) gamma scintigraphy...
journal_title:British journal of cancer
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