Abstract：
:Pain and discomfort are common and often severe skin symptoms in patients with psoriasis. However, no studies have investigated skin pain and discomfort over time, or factors that explain changes in these symptoms. The aims of the present study were to describe the changes in skin pain, skin discomfort and Psoriasis Area and Severity Index (PASI) over time, and to investigate whether change in PASI predicted change in skin pain intensity. A total of 129 patients participated in this exploratory, longitudinal study. Data were obtained through interviews and questionnaires. The results indicated reduction in skin symptoms and psoriasis severity over a period of 3 months. However, a majority of patients with skin pain at baseline reported also skin pain at follow-up. Furthermore, changes in PASI predicted changes in skin pain intensity. In conclusion, improvement in psoriasis severity predicts improvement in skin pain.
journal_name
Acta Derm Venereoljournal_title
Acta dermato-venereologicaauthors
Ljosaa TM,Stubhaug A,Mork C,Moum T,Wahl AKdoi
10.2340/00015555-1456subject
Has Abstractpub_date
2013-05-01 00:00:00pages
330-4issue
3eissn
0001-5555issn
1651-2057journal_volume
93pub_type
杂志文章abstract：:Irritant contact dermatitis is a major problem in dermatology. One important group of substances causing irritant dermatitis is detergents. Exposure of the skin to detergents is frequent in both work and domestic environments. In the present paper we have studied how the penetration through the skin, and thus the effe...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555573203207
更新日期：1993-06-01 00:00:00
abstract：:Forty-three nickel-allergic patients (40 females and 3 males) participated in this study which was designed to elucidate the correlation between quantitative in vivo and in vitro responses. All were patch-tested with various concentrations of nickel-sulphate serial-diluted in water. The lowest concentration eliciting ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Sympathetic dysfunction and skin microvascular arteriovenous shunting with insufficient nutritive perfusion and tissue hypoxia have been reported in patients with erythromelalgia. The objective of this study was to determine whether iloprost, a synthetic prostacyclin analogue--primarily a vasodilator and inhibitor of ...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/00015550310015031
更新日期：2003-01-01 00:00:00
abstract：:Anti-interleukin-17 agents have recently been developed for the treatment of psoriasis. This study evaluated the tolerance and effectiveness of anti-interleukin-17 agents for psoriasis in elderly patients in daily practice. A multicentre, retrospective study was performed, involving psoriatic patients aged ≥65 years w...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-3678
更新日期：2020-11-04 00:00:00
abstract：:The possibility that topically-applied minoxidil might affect the growth cycle of hair follicles was studied in inbred Herston white mice and HRA/Skh1 hairless mice. In the normal follicular cycle, the anagen or growth phase can be followed by autoradiographic demonstration of [3H]thymidine uptake in proliferating mat...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Two cases of subacute cutaneous lupus erythematosus are described. Features which delayed diagnosis are discussed. The potential clinical and histopathological overlap between this condition and erythema multiforme is emphasized, drawing attention to the histological features which allow distinction. The possibility t...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/00015559850135869
更新日期：1998-01-01 00:00:00
abstract：:Loricrin, the major component of the cornified envelope, is normally expressed in the granular layer of epidermis during the last steps of keratinocyte differentiation. Using an antiloricrin antiserum (A8-73), an increased expression of this envelope precursor was found in some disorders of hyperorthokeratosis (ichthy...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：102340/0001555572407409
更新日期：1992-11-01 00:00:00
abstract：:Irritation and staining, the side effects of dithranol and related compounds have previously been studied after a single chamber-exposure. To mimic the therapeutic situation, the chamber application was repeated for 3 weeks on the uninvolved back skin of 17 psoriasis patients. In equimolar concentrations corresponding...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:The aromatic retinoids etretinate and acitretin are widely used in the systemic treatment of severe psoriasis. The purpose of the present investigation was to further elucidate the mode of action of acitretin on abnormal keratinization and epidermal hyperproliferation in an in vivo model. Studies on the interference o...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/000155557669
更新日期：1996-01-01 00:00:00
abstract：:The 8-methoxypsoralen (8-MOP) plasma level was determined in 31 patients during treatment with PUVA (psoralen + UVA light). The UVA light source was of a low intensity type, giving only 2 mW/sec/cm2 and required an irradiation time of 30 minutes. The lesions of 19 patients healed completely. Following an oral dose reg...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Alexithymia, defined as difficulty in describing or recognizing emotions, has been shown to be connected with psoriasis, but its relationship with self-management of psoriasis has not been explored. The aim of this study was to assess the frequency of alexithymia and its relationship with self-management and illness p...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章,随机对照试验
doi：10.2340/00015555-2707
更新日期：2017-08-31 00:00:00
abstract：:The skin reactions to skin provocation tests with 11 primary irritants were compared in 21 pairs of men and women with hand eczema, matched for age, and in 21 pairs of non-eczematous subjects. With a few exceptions, no statistically significant differences were demonstrated in the intensities of the skin reactions bet...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：102340/0001555555191194
更新日期：1975-01-01 00:00:00
abstract：:The effect of five corticosteroid ointments on epidermal thickness was studied using occlusive chamber application. Thinning of the epidermis and telangiectasia were noted 3 weeks after application of betamethasone-17-valerate (BV), budesonide (BD), clobetasol-17-propionate (CP), and fluocinolone acetonide (FA), but n...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Patients with rheumatoid arthritis were investigated for contact allergy to gold in connection with treatment with gold preparations. There were 57 patients with rheumatoid arthritis previously treated with gold, with or without cutaneous side-effects, as well as 20 patients intended for such treatment; all were expos...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章
doi：10.2340/0001555577370373
更新日期：1997-09-01 00:00:00
abstract：:Many patients with psoriasis demonstrate psychological disturbances, including decreased health-related quality of life (HRQoL). The aim of this study was to evaluate selected personal resources and HRQoL in 168 in-patients with psoriasis vulgaris. The following questionnaires were used: Skindex-29, General Health Que...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-1530
更新日期：2013-09-04 00:00:00
abstract：:Pruritus is exacerbated at night in many systemic and dermatological diseases, resulting in reports of significantly diminished quality of life and sleep disturbances. At present, the underlying mechanisms responsible for night-time itching are not well understood. Nocturnal pruritus may be related to the circadian rh...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章,评审
doi：10.2340/00015555-0280
更新日期：2007-01-01 00:00:00
abstract：:Only animal experiments have been published regarding the possible effect of penicillamine treatment on mineral balance. We examined 35 patients with a diagnosis of systemic sclerosis treated with penicillamine, in comparison with 10 patients with systemic sclerosis treated with other collagen inhibitors (glutamine, h...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:There has been no previous systematic study of bullous skin diseases with granular basement membrane zone deposition exclusively of C3. In this study we collected 20 such patients, none of whom showed cutaneous vasculitis histopathologically. Oral dapsone and topical steroids were effective. Various serological tests ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-2379
更新日期：2016-08-23 00:00:00
abstract：:Atopic dermatitis (AD) and impetigo are skin conditions where bacterial colonisation and infection, especially with Staphylococcus aureus play an important role. We compared skin bacterial population, resistance patterns and choice of antimicrobial agents in patients diagnosed with AD and impetigo during 2005 and 2011...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-1996
更新日期：2015-05-01 00:00:00
abstract：:Peripheral blood lymphocytes from 45 patients with a positive patch test to cobalt chloride (CoCl2) and 37 controls were stimulated with various concentrations of CoCl2 and/or cobalt sulphate (CoSO4) or cobalt nitrate (Co(NO3)2) or cobalt acetate [CH3COO)2Co) for various days in culture. Lymphocytes from 35 of these p...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Psychological stress and atopic dermatitis (AD) symptoms appear to form a vicious cycle. This study compared the degree of stress and impairment of dermatology life quality between patients with AD and healthy controls, and examined for neuropeptides and neurotrophins associated with stress in AD. Questionnaires, comp...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-0933
更新日期：2010-11-01 00:00:00
abstract：:Digitonin, which is known to cause extensive damage to cytomembranes in general, was found to have a most remarkable effect on epidermal Langerhans' cells. Thus, it generates a membrane-sandwiching process resulting in the formation of large discs which except for the differences in size have the same morphology as or...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Patients with X-linked recessive ichthyosis (RXLI) were studied as a model of the effect of disturbed epidermal lipid composition on skin barrier function. Thirteen patients with RXLI and 15 age- and sex-matched controls were patch-tested with sodium lauryl sulphate (SLS) 0.5% for 24 h. Basal skin properties and skin ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555575198201
更新日期：1995-05-01 00:00:00
abstract：:A 73-year-old woman with rheumatoid arthritis was treated with Levamisole, 150 mg per day, on 2 days a week. Her arthritis improved, but she developed a severely itching rash, and the treatment was stopped after 6 months. Penicillamine was subsequently given and tolerated without skin complications. 15 months after re...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:The effect on dermographic wealing of an H1 and H2 receptor antagonist was studied separately and in combination. a double-blind protocol was used and dermographism was measured as the diameter of weal response to a measured force. Both H1 and H2 antagonists had a small but non-significant effect, but the combination ...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1983-01-01 00:00:00
abstract：:Aryl hydrocarbon hydroxylase (AHH) and glutathione S-transferase (GST) (EC 2.5.1.18) activity were measured in human lymphocytes of peripheral blood from 8 patients with irritant or allergic contact dermatitis of the hands, and compared with data from a control group. Both AHH and GST activity was found to be signific...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Zinc deficiency was produced in rats by feeding them a diet containing 0.5 mg zinc per kg. After 2 weeks the zinc-deficient rats showed markedly stunted growth as compared with control rats receiving an identical diet supplemented with 50 mg zinc per kg. After about 3 weeks all rats in the zinc-deficient group develop...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Actinomycotic mycetomas usually respond slowly to treatment with antibiotics. In an attempt to hasten clinical resolution, we used a 2-step regimen consisting of an intensive phase of therapy with penicillin, gentamycin and co-trimoxazole for 5-7 weeks, followed by maintenance therapy with amoxicillin and co-trimoxazo...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155500459367
更新日期：2000-09-01 00:00:00
abstract：:A leukoplakic lesion of the prepuce is described with the histologic and ultrastructural features of epidermolytic hyperkeratosis. The lesion represents most likely a variant of epidermolytic leukoplakia recently observed in the vermilion border of the lip. ...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Suction blisters were raised in lesions and normal appearing skin of patients with psoriasis. The blister roof which contains the epidermis separated at the dermal-epidermal junction was stained with ATPase, OKT-6 and anti-HLA-DR monoclonal antibodies. The technique permits the counting of the Langerhans' cells per mm...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
