Continuous 24-hour assessment of the neural regulation of systemic arterial pressure and RR variabilities in ambulant subjects.

abstract：:To examine whether or not magnesium suppresses coronary spasm, the effect of magnesium infusion on anginal attacks induced by hyperventilation was studied in 20 patients with variant angina. In all patients, anginal attacks associated with ischemic ST segment changes on the electrocardiogram were repeatedly induced by...

journal_title：Circulation

authors： Miyagi H,Yasue H,Okumura K,Ogawa H,Goto K,Oshima S

更新日期：1989-03-01 00:00:00

abstract：:The ameliorative effect of antiplatelet therapy on atherogenesis of vein grafts was assessed in autologous cephalic veins grafted into femoral arteries of 16 normolipemic and 11 hyperlipemic stump-tailed macaque monkeys. Before grafting, one half of each vein was distended at high pressure (700 mm Hg) and the other ha...

journal_title：Circulation

authors： Bonchek LI,Boerboom LE,Olinger GN,Pepper JR,Munns J,Hutchinson L,Kissebah AH

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:Although the dominant product of vascular Cyclooxygenase-2 (COX-2), prostacyclin (PGI(2)), restrains atherogenesis, inhibition and deletion of COX-2 have yielded conflicting results in mouse models of atherosclerosis. Floxed mice were used to parse distinct cellular contributions of COX-2 in macrophages and ...

journal_title：Circulation

authors： Hui Y,Ricciotti E,Crichton I,Yu Z,Wang D,Stubbe J,Wang M,Puré E,FitzGerald GA

更新日期：2010-06-22 00:00:00

abstract：:This review discusses the role of growth factors on the proliferation of smooth muscle cells (SMCs) in injured arteries. We have used a variety of procedures to injure rat carotid arteries and noted that removal of endothelium followed by platelet adherence does not always initiate SMC replication. Furthermore, thromb...

journal_title：Circulation

authors： Reidy MA,Fingerle J,Lindner V

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Isomerism is associated with a complex spectrum of anomalies. There is paucity of data on prenatally detected cases. METHODS AND RESULTS:Between January 1990 and February 2004, 83 of 166 cases (50%) had a prenatal diagnosis of left isomerism (LAI; 52 of 97) or right isomerism (RAI; 31 of 69) at our institut...

journal_title：Circulation

authors： Lim JS,McCrindle BW,Smallhorn JF,Golding F,Caldarone CA,Taketazu M,Jaeggi ET

更新日期：2005-10-18 00:00:00

abstract：BACKGROUND:Atherosclerosis is a multifactorial disorder involving inflammatory processes. These responses are associated with robust activation of signaling cascades by diverse cell surface receptors in a variety of cell types. The processes that are involved in atherosclerosis would likely require intact Ras pathways,...

journal_title：Circulation

authors： George J,Afek A,Keren P,Herz I,Goldberg I,Haklai R,Kloog Y,Keren G

更新日期：2002-05-21 00:00:00

abstract：BACKGROUND:Catheter-based intrapericardial (IPC) delivery of therapeutic agents has recently been demonstrated. Paclitaxel is known to inhibit vascular smooth muscle cell proliferation. This study examined the effect of IPC instillation of paclitaxel on neointimal proliferation after balloon overstretch of porcine coro...

journal_title：Circulation

authors： Hou D,Rogers PI,Toleikis PM,Hunter W,March KL

更新日期：2000-09-26 00:00:00

abstract：BACKGROUND:Regional variation in the incidence and outcomes of in-hospital cardiac arrest (IHCA) is not well studied and may have important health and policy implications. METHODS AND RESULTS:We used the 2003 to 2011 Nationwide Inpatient Sample databases to identify patients≥18 years of age who underwent cardiopulmona...

journal_title：Circulation

authors： Kolte D,Khera S,Aronow WS,Palaniswamy C,Mujib M,Ahn C,Iwai S,Jain D,Sule S,Ahmed A,Cooper HA,Frishman WH,Bhatt DL,Panza JA,Fonarow GC

更新日期：2015-04-21 00:00:00

abstract：:The relation between ventricular dysrhythmia during the first 20 hours after hospitalization for acute myocardial infarction and enzymatically estimated infarct size was studied prospectively. The duration of dyshythmia was measured by the total time during which the average premature ventricular depolarization (PVC) ...

journal_title：Circulation

authors： Cox JR Jr,Roberts R,Ambos HD,Oliver GC,Sobel BE

更新日期：1976-03-01 00:00:00

abstract：:The predictive value of the myocardial scintigraphy with 99mTc-pyrophosphate was studied in 100 patients admitted to the coronary care unit with suspected acute myocardial infarction. None of the 21 patients with normal scintigrams had acute myocardial infraction by other criteria. Fifty-five percent of patients with ...

journal_title：Circulation

authors： Holman BL,Chisholm RJ,Braunwald E

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Two hundred eighteen patients were evaluated in a two-phase approach (time to first appropriate discharge, survival after discharge) to identify factors that may be related to maximal benefit derived from use of an automatic implantable cardioverter-defibrillator (AICD). METHODS AND RESULTS:One hundred nine...

journal_title：Circulation

authors： Levine JH,Mellits ED,Baumgardner RA,Veltri EP,Mower M,Grunwald L,Guarnieri T,Aarons D,Griffith LS

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Current studies have demonstrated that applying therapeutic hypothermia for 12 to 24 hours after resuscitation from cardiac arrest improves the outcomes of cardiopulmonary resuscitation. The present study investigated whether a shorter duration of therapeutic hypothermia induced quickly and early after resus...

journal_title：Circulation

authors： Ye S,Weng Y,Sun S,Chen W,Wu X,Li Z,Weil MH,Tang W

更新日期：2012-01-03 00:00:00

abstract：:Prospective data was recorded on 217 percutaneous transluminal angioplasty (PTA) procedures performed in the superficial femoral and popliteal arteries over an 8-year period. After the initial procedure, patients were followed with serial noninvasive studies and, in 71 patients, repeat angiography. The mean follow-up ...

journal_title：Circulation

authors： Capek P,McLean GK,Berkowitz HD

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Associations of obesity with incidence of heart failure have been observed, but the causality is uncertain. We hypothesized that gastric bypass surgery leads to a lower incidence of heart failure compared with intensive lifestyle modification in obese people. METHODS:We included obese people without previou...

journal_title：Circulation

authors： Sundström J,Bruze G,Ottosson J,Marcus C,Näslund I,Neovius M

更新日期：2017-04-25 00:00:00

abstract：:While continuing a study of immunologic and virologic aspects of the postpericardiotomy syndrome (PPS) in infants and children, we undertook a companion study in adults. Whereas the incidence in 119 children was 27.8%, as is usual for our hospital, the incidence in 142 adults was 17.6%. Most of the operations (95 of 1...

journal_title：Circulation

authors： Engle MA,Gay WA Jr,McCabe J,Longo E,Johnson D,Senterfit LB,Zabriskie JB

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Coronary heart disease (CHD) represents the largest share of cardiovascular disease in the United States, but there are conspicuous discrepancies between CHD and total cardiovascular death rates across the states, possibly due in part to variations in physician assignment of causes of death. Our aim was to i...

journal_title：Circulation

authors： Murray CJ,Kulkarni SC,Ezzati M

更新日期：2006-05-02 00:00:00

abstract：:Twenty-one patients with documented coronary atherosclerotic heart disease were studied to determine the effect of high dose oral isosorbide dinitrate (ISDN) on heart rate, blood pressure, and exercise time until angina pectoris. Patients were tested in two phases, initially with 0.4 mg of sublingual nitroglycerin and...

journal_title：Circulation

authors： Danahy DT,Burwell DT,Aronow WS,Prakash R

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Heart failure is a leading cause of death worldwide. Cyclic nucleotide phosphodiesterases (PDEs), through degradation of cyclic nucleotides, play critical roles in cardiovascular biology and disease. Our preliminary screening studies have revealed PDE10A upregulation in the diseased heart. However, the roles...

journal_title：Circulation

authors： Chen S,Zhang Y,Lighthouse JK,Mickelsen DM,Wu J,Yao P,Small EM,Yan C

更新日期：2020-01-21 00:00:00

abstract：:The disparate effects of social determinants of health on cardiovascular health status and health care have been extensively documented by epidemiology. Yet, very little attention has been paid to how understanding and addressing social determinants of health might improve the quality of clinical interactions, especia...

journal_title：Circulation

authors： Kressin NR,Chapman SE,Magnani JW

更新日期：2016-06-14 00:00:00

abstract：BACKGROUND:Coxsackieviruses B (CBVs) are dominant causative agents in myocarditis and are associated with pathogenesis is some cases of dilated cardiomyopathy, a clinical entity with a poor survival without heart transplantation. METHODS AND RESULTS:In vitro, the antiviral agent WIN 54 954 was shown to inhibit replica...

journal_title：Circulation

authors： Fohlman J,Pauksen K,Hyypiä T,Eggertsen G,Ehrnst A,Ilbäck NG,Friman G

更新日期：1996-11-01 00:00:00

abstract：INTRODUCTION:Patients with congenital heart disease frequently require graft material for repair of cardiac defects. However, currently available grafts lack growth potential and are noncontractile and thrombogenic. We have developed a viable cardiac graft that contracts spontaneously in tissue culture by seeding cells...

journal_title：Circulation

authors： Li RK,Jia ZQ,Weisel RD,Mickle DA,Choi A,Yau TM

更新日期：1999-11-09 00:00:00

abstract：BACKGROUND:Abnormal vascular reactivity represents a fundamental disturbance in vascular biology with the development of atherosclerosis. Because endothelial vasodilator function plays a pivotal role in controlling vasomotor tone, we hypothesized that atherosclerotic wall thickening might directly interfere with defici...

journal_title：Circulation

authors： Zeiher AM,Schächlinger V,Hohnloser SH,Saurbier B,Just H

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Erythropoietin (Epo) receptors (EpoRs) are expressed in the heart. We have recently demonstrated that the endogenous Epo-EpoR system plays an important protective role in myocardial ischemia in mice and humans. In the present study, we tested our hypothesis that the endogenous Epo-EpoR system in nonhematopoi...

journal_title：Circulation

authors： Asaumi Y,Kagaya Y,Takeda M,Yamaguchi N,Tada H,Ito K,Ohta J,Shiroto T,Shirato K,Minegishi N,Shimokawa H

更新日期：2007-04-17 00:00:00

abstract：BACKGROUND:Myocardial perfusion reserve can be noninvasively assessed with cardiovascular MR. In this study, the diagnostic accuracy of this technique for the detection of significant coronary artery stenosis was evaluated. METHODS AND RESULTS:In 15 patients with single-vessel coronary artery disease and 5 patients wi...

journal_title：Circulation

authors： Al-Saadi N,Nagel E,Gross M,Bornstedt A,Schnackenburg B,Klein C,Klimek W,Oswald H,Fleck E

更新日期：2000-03-28 00:00:00

abstract：BACKGROUND:The clinical efficacy of alcohol septal ablation for drug-refractory hypertrophic cardiomyopathy remains unclear. This study examines the outcome of alcohol septal ablation performed at a tertiary hypertrophic cardiomyopathy referral center. METHODS AND RESULTS:Among 601 patients with severely symptomatic o...

journal_title：Circulation

authors： Sorajja P,Valeti U,Nishimura RA,Ommen SR,Rihal CS,Gersh BJ,Hodge DO,Schaff HV,Holmes DR Jr

更新日期：2008-07-08 00:00:00

abstract：BACKGROUND:The degree of protection provided to the right ventricle during retrograde continuous normothermic blood cardioplegia (RCNBC) remains controversial. The purpose of this study was to determine whether RCNBC is able to provide "adequate" nutritive flow to both ventricles to prevent ischemic metabolism in norma...

journal_title：Circulation

authors： Ye J,Sun J,Shen J,Gregorash L,Summers R,Salerno TA,Deslauriers R

更新日期：1997-11-04 00:00:00

abstract：:In previous studies from this laboratory, we found that approximately 30% of women with chest pain and normal coronary arteries demonstrated either a decrease in or a failure to increase radionuclide ejection fraction during exercise. To examine the hypothesis that this apparent abnormality in left ventricular functio...

journal_title：Circulation

authors： Higginbotham MB,Morris KG,Coleman RE,Cobb FR

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:High C-reactive protein (CRP) levels are associated with an increased risk of cardiovascular events, even in apparently healthy individuals. It has not been established whether elevated CRP reflects an increased burden of subclinical coronary atherosclerosis. METHODS AND RESULTS:We studied a stratified rand...

journal_title：Circulation

authors： Wang TJ,Larson MG,Levy D,Benjamin EJ,Kupka MJ,Manning WJ,Clouse ME,D'Agostino RB,Wilson PW,O'Donnell CJ

更新日期：2002-09-03 00:00:00

abstract：BACKGROUND:The treatment of unstable angina targets the specific pathophysiological thrombotic process at the site of the active culprit lesion. In unstable angina due to a restenotic lesion, smooth muscle cell proliferation and increased vasoreactivity may play a more important role than thrombus formation. Therefore,...

journal_title：Circulation

authors： Doucet S,Malekianpour M,Théroux P,Bilodeau L,Côté G,de Guise P,Dupuis J,Joyal M,Gosselin G,Tanguay JF,Juneau M,Harel F,Nattel S,Tardif JC,Lespérance J

更新日期：2000-03-07 00:00:00

abstract：:Endocardial catheter mapping was performed in 15 patients in sinus rhythm who had no evidence of structural heart disease and normal left ventricles. Mapping was performed with the use of 10 mm interelectrode distance from various left ventricular endocardial sites. In 10 patients a quantitative analysis of electrogra...

journal_title：Circulation

authors： Cassidy DM,Vassallo JA,Marchlinski FE,Buxton AE,Untereker WJ,Josephson ME

更新日期：1984-07-01 00:00:00