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Transformation of 8-prenylnaringenin by Absidia coerulea and Beauveria bassiana.

Abstract：

:Beauveria bassiana AM278 and Absidia coerulea AM93 converted 8-prenylnaringenin (1) into two glycoside derivatives (7-O-β-D-glucopyranoside) (2) and 7-O-β-D-4'''-O-methylglucopyranoside) (3) in high yields in processes conducted in Saboraud medium. 8-Prenylnaringenin 7-O-β-D-4'''-O-methylglucopyranoside (3) is a new compound. 8-Prenylnaringenin-7-sulfate (4) was obtained in transformation of 1 by Absidia coerulea AM93 in a buffer. Formation of conjugated products in this study proceeds in a manner analogous to mammalian systems which indicates the potential use of microbes to mimic mammalian metabolism.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Bartmańska A,Tronina T,Huszcza E

doi

10.1016/j.bmcl.2012.08.060

subject

Has Abstract

pub_date

2012-10-15 00:00:00

pages

6451-3

issue

20

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(12)01060-8

journal_volume

22

pub_type

杂志文章

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