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Incidence and short-term mortality from perforated peptic ulcer in Korea: a population-based study.

Abstract：

BACKGROUND:Perforated peptic ulcer (PPU) is associated with serious health and economic outcomes. However, few studies have estimated the incidence and health outcomes of PPU using a nationally representative sample in Asia. We estimated age- and sex-specific incidence and short-term mortality from PPU among Koreans and investigated the risk factors for mortality associated with PPU development. METHODS:A retrospective population-based study was conducted from 2006 through 2007 using the Korean National Health Insurance claims database. A diagnostic algorithm was derived and validated to identify PPU patients, and PPU incidence rates and 30-day mortality rates were determined. RESULTS:From 2006 through 2007, the PPU incidence rate per 100 000 population was 4.4; incidence among men (7.53) was approximately 6 times that among women (1.24). Incidence significantly increased with advanced age, especially among women older than 50 years. Among 4258 PPU patients, 135 (3.15%) died within 30 days of the PPU event. The 30-day mortality rate increased with advanced age and reached almost 20% for patients older than 80 years. The 30-day mortality rate was 10% for women and 2% for men. Older age, being female, and higher comorbidity were independently associated with 30-day mortality rate among PPU patients in Korea. CONCLUSIONS:Special attention should be paid to elderly women with high comorbidity who develop PPU.

journal_name

J Epidemiol

journal_title

Journal of epidemiology

authors

Bae S,Shim KN,Kim N,Kang JM,Kim DS,Kim KM,Cho YK,Jung SW

doi

10.2188/jea.je20120056

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

508-16

issue

6

eissn

0917-5040

issn

1349-9092

pii

DN/JST.JSTAGE/jea/JE20120056

journal_volume

22

pub_type

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